A freeze-drying system includes a vented cart for operation in a pressure-controlled chamber, and a plurality of heated shelves disposed in the vented cart. Each heated shelf includes a planar sheet made from a thermally conductive material. The planar sheet is folded to provide a top portion configured to conduct heat to a tray resting on the top portion, a bottom portion disposed opposite the top portion, and a folded leading edge. A heating element is secured between the top portion and the bottom portion so as to be disposed in thermally conductive contact with either the top portion or the bottom portion. The top portion is configured to conduct heat to a tray resting on the top portion. The leading folded edge permits food items to slide out of the freeze-drying system, even though pressing along the bottom portion of the heated shelf, without catching on the food.

The present invention relates to a process for the production of a device (1) for dispensing eye drops. The process comprises the steps of: providing a first container (2) and a second container (3) configured to be engaged in a fluid-tight manner, providing a spacer (4), introducing a water-based solution (200) inside the first container (2), introducing a solution or dispersion comprising a drug inside the second container (3), arranging the spacer (4) between the first and second containers (2, 3), engaging in a fluid-tight manner the second container (3) and the first container (2); and freeze-drying the solution or dispersion comprising the drug.

A method of preparing a pharmaceutical product in a single multiple chamber flexible bag. A pharmaceutical product is introduced in a liquid state into a first chamber of the flexible bag through a first port. The pharmaceutical product is lyophilized within the first chamber of the flexible bag to provide a lyophilized pharmaceutical product. The flexible bag has a second chamber and the first chamber and the second chamber are separated by a breakable seal. The second chamber further includes a reconstituting solution for reconstituting the lyophilized pharmaceutical product in the first chamber. A user may apply pressure to the flexible bag to break the seal and mix the lyophilized pharmaceutical product and the reconstituting solution to order to administer the pharmaceutical product to a patient.

A multiple chamber flexible pharmaceutical bag includes a front film and a back film joined to the front film around a perimeter of the pharmaceutical bag to define a first chamber holding a lyophilized pharmaceutical product and a second chamber holding a reconstituting solution for reconstituting the lyophilized pharmaceutical product held in the first chamber. The pharmaceutical bag includes a seal disposed between the first chamber and the second chamber and defining a connection between the front film of the pharmaceutical bag and the back film of the pharmaceutical bag. The seal breaks when a predetermined amount of force is applied to the pharmaceutical bag such that the connection between the front surface and the back surface of the pharmaceutical bag is torn apart to fluidly connect the second chamber to the first chamber. The front film, the back film, and the seal are comprised of the same material.

Various embodiments of freeze dryers and drying processes are disclosed that can be used to dry materials with low water content (no more than 20 wt % water) and/or high sugar content (at least 20 wt % sugar). Such materials include candy, confections, and the like. In one embodiment, a drying process includes drying the materials without freezing them. In another embodiment, a drying process includes warming the materials before drying them. In another embodiment, a drying process includes drying two batches of materials with low water content sequentially without defrosting the interior of freeze dryer.

Various embodiments of freeze dryers and drying processes are disclosed that can be used to dry materials with low water content (no more than 20 wt % water) and/or high sugar content (at least 20 wt % sugar). Such materials include candy, confections, and the like. In one embodiment, a drying process includes drying the materials without freezing them. In another embodiment, a drying process includes warming the materials before drying them. In another embodiment, a drying process includes drying two batches of materials with low water content sequentially without defrosting the interior of freeze dryer.

The present disclosure discloses a vacuum drying tank, including a shell and a pumping device. The shell includes a first shell part, a second shell part, and a third shell part; the second shell part has an accommodating cavity provided with an opening in the top; an air pumping hole is formed in the accommodating cavity; the first shell part is, hermetically covered at the opening; the third shell part is arranged below the second shell part; the pumping device is arranged in the third shell part and is communicated with the air pumping hole; and the pumping device is used for pumping out air in the accommodating cavity from the air pumping hole, so that the accommodating cavity is in a vacuum state.

A method of preparing a pharmaceutical product in a single multiple chamber flexible bag. A pharmaceutical product is introduced in a liquid state into a first chamber of the flexible bag through a first port. The pharmaceutical product is lyophilized within the first chamber of the flexible bag to provide a lyophilized pharmaceutical product. The flexible bag has a second chamber and the first chamber and the second chamber are separated by a breakable seal. The second chamber further includes a reconstituting solution for reconstituting the lyophilized pharmaceutical product in the first chamber. A user may apply pressure to the flexible bag to break the seal and mix the lyophilized pharmaceutical product and the reconstituting solution to order to administer the pharmaceutical product to a patient.

Disclosed herein is a device for multianalyte detection, and systems and methods for drying reagents in wells in the device in a manner that preserves functional performance. Specifically, disclosed is a system for drying reagents in the wells of a multiwell plate. The multiwell plate is sprayed with air from nozzles positioned above the multiwell plate. Air is exhausted evenly below the multiwell plate. This allows for the rapid, consistent drying of large volumes of liquid in the well of a multiwell plate.