G01N2015/0038

Bioparticle measuring method

The present disclosure relates to a bioparticle measuring method including detecting a signal from a first measurement sample and a signal from a second measurement sample, wherein the first measurement sample is prepared by mixing a first sample containing a bioparticle sampled from a specimen with a detector capable of binding to the bioparticle and containing a labeled substance, in the presence of an inhibitor capable of binding to the bioparticle and containing none of the labeled substance. The second measurement sample is prepared by mixing a second sample sampled from the same specimen independently from the first sample with the detector, under a condition that the inhibitor is substantially absent. A measurement result is then calculated from the detected signals from the first and second measurement samples.

System and method of use for electrically differentiating particles in a liquid

A system for the differentiation of plastic and non-plastic particles in suspension in a liquid, and the method of use thereof. The system having a channel for constraining and presenting the liquid to a detector, the detector having at least one transmit electrode for emitting electrical current to at least one receive electrode. Circuitry provides the current input and received electrical signals measurement capacities. Particles passing the receive electrodes alter the received electrical current according to the particle's dielectric properties, the circuitry records the received signals and discerns a particle's nature, most often plastic from non-plastic, from the differential signal of these received signals as a function of frequency.

METHOD OF PRODUCING REACTION UNIT, KIT FOR PRODUCING REACTION UNIT, AND METHOD OF MEASURING DETECTION TARGET SUBSTANCE
20220364974 · 2022-11-17 ·

A method of producing a reaction unit includes (a1) preparing a first substrate which is a substrate having a first surface and a second surface and of which at least the first surface is composed of polypropylene, and which has one or more through-holes that penetrate from the first surface to the second surface, and a second substrate which is a substrate having a first surface and a second surface and of which at least the first surface is composed of at least one selected from the group consisting of cycloolefin polymers and cycloolefin copolymers, and which has a track region in which concave parts and convex parts are alternately formed on the first surface; (b1) applying a photocurable composition around an opening of the through-hole on the first surface of the first substrate; (c1) emitting light to the photocurable composition applied around the opening of the through-hole to form a cured resin layer in which the photocurable composition is cured; and (d1) forming a well having the track region as a bottom surface and the through-hole as a side surface, which is a well formed by bringing the cured resin layer formed on the first surface of the first substrate into close contact with the first surface of the second substrate after the process (c1).

FLUID SENSOR SYSTEM
20220365019 · 2022-11-17 ·

The present disclosure provides a fluid sensor and a method for fabricating a fluid sensor. The fluid sensor includes a substrate including a first material and having a first surface and a second surface opposite to the first surface, wherein the substrate further comprises a recess recessed from the first surface, a first conductive layer over the first surface of the substrate, a protection layer between the first surface of the substrate and the first conductive layer, wherein the protection layer includes a second material, and a through via connected to the recess.

Synthesis of nano particles

A method for synthesis of nanoparticles are described. The method includes dispersing metal oxide powder in a mixture of a base liquid and a surfactant to form a primary mixture, grinding the primary mixture using a grinding media by periodically adding a surfactant solution to form a slurry, extracting a predetermined amount of sample from the slurry at periodic time intervals to obtain a testing solution to assess particle size of in the slurry using a particle size analyzer; and systematically adding the surfactant solution and the grinding media to the slurry based on the assessed particle size in the testing solution until a mean particle size of the nanoparticles is achieved.

Nanoparticle control and detection system and operating method thereof

The present invention discloses a nanoparticle control and detection system and operating method thereof. The present invention controls and detects the nanoparticles in the same device. The device comprises a first transparent electrode, a photoconductive layer, a spacer which is deposed on the edge of the photoconductive layer and a second transparent electrode. The aforementioned device controls and detects the nanoparticles by applying AC/DC bias and AC/DC light source to the transparent electrode.

Devices and methods of use thereof

Described herein are devices and methods of use thereof, the devices comprising: a sample conduit providing a path for fluid flow extending from a sample inlet to a sample outlet; a thermal housing enclosing the sample conduit, the thermal housing comprising a plurality of measurement regions; and a motorized stage translatable along the thermal housing so as to align a detector with one or more of the plurality of measurement regions. The devices can continuously flow a fluid precursor sample from the sample inlet to the sample outlet, the fluid precursor sample comprising a first precursor and a second precursor, such that the first precursor reacts with the second precursor as the fluid precursor sample continuously flows from the sample inlet to the sample outlet to form the sample before reaching the sample outlet, wherein the sample comprises a plurality of particles or an organic molecule.

DEVICE FOR REMOVING BIOMATERIAL
20220347625 · 2022-11-03 ·

Provided is a biomaterial removing device including an air injection part, a first processing part spaced apart from the air injection part, and a second processing part spaced apart from the air injection part with the first processing part therebetween, wherein the first processing part includes a first biomaterial removing part configured to remove biomaterials included in air collected from the air injection part and a first monitoring part, and the second processing part includes a second biomaterial removing part configured to remove the residual biomaterials and a second monitoring part, wherein the first biomaterial removing part includes a dry air purifier, the second biomaterial removing part includes a wet air purifier, and the first biomaterial removing part and the second biomaterial removing part each include an image sensor.

Miniaturized flow cell and system for single-molecule nanoconfinement and imaging

Nanofluidic flow cells and systems for single-molecule nanoconfinement and imaging of molecules in a fluid are described. The nanofluidic flow cell comprises a bottom substrate bonded to a top substrate, microchannels and a central chamber carved in the bottom or top substrate. The microchannels and the central chamber define an empty space into which a fluid can flow. The microchannels extend on opposite side of the central chamber, each microchannel comprising a central portion crossing the central chamber and a pair of arms extending outside the central chamber, these arms comprising a fluid port positioned at opposite ends of the microchannel and outside the central chamber. The central chamber comprises a nanoconfinement and imaging area including carved nanostructures configured for single-molecule nanoconfinement. Also described are nanofluidic chips, methods of confinement, pneumatic-based nanofluidic systems and manifold assembly for the nanofluidic flow cell.

Method for imaging biological tissue using polarized majorana vector and complex vortex photons from laser and supercontinuum light sources
11614398 · 2023-03-28 · ·

A super class of polarized transverse vector vortex photon beams patterns are mathematically represented here, which are Majorana-like among them are the radial and azimuthal Laguerre-Gaussian, hybrid π-vector beams, and Airy beams. These optical beams are consider spin-orbit coupled beams based on OAM and SAM parts of light. A Majorana photon is a photon that is identical to its anti-photon. It has within itself both chirality, right and left-handed twist in polarization (SAM) and wavefront (OAM). Applications using Majorana photons improve optical deeper imaging, higher resolution imaging, Nonlinear Optics effects (SHG, SRS, SC), optical communication in free space and fibers, quantum computer as basic qubit, and entanglement for security.