A magneto-quasistatic field may be used to align hydrogen of materials within a structure and/or to disrupt the alignment of hydrogen of materials within the structure. Realignment of the hydrogen after the disruption may cause emission of energy from the hydrogen. The characteristic(s) of the energy may be detected and used to generate image(s) of interior portion(s) of the structure.

Disclosed is a method for determining fibre porosity in a fibre suspension. A sample is taken from a fibre suspension and fibre porosity determination is performed by determining the ratio of fibre-internal water to fibre-external bound water as an online measurement using a NMR spectroscope in successive steps of: generating a magnetic field for exciting protons of water contained in the sample; exciting water molecules of fibre suspension contained in the sample with a frequency pulse provided by a coil; measuring a return signal of the frequency pulse that returns from water molecules to the coil; determining the proton relaxation time and the amplitude of the return signal from the return signal; and determining fibre porosity of the fibre suspension based on the amplitude and the relaxation time of the exponential return signal. Also disclosed is a device for determining fibre porosity of a fibre suspension and a control system connected to a fibre web machine.

An experimental technology for detecting a hydrogen bond based on an ssNMR technology includes: (1) exciting a .sup.1H nucleus of an RNA sample with a π/2 pulse; (2) applying two π pulses every half rotation period on an X_nucleus of the RNA sample; (3) applying a π pulse on the .sup.1H nucleus of the RNA sample; (4) applying two π pulses every half rotation period on the X nucleus of the RNA sample; (5) applying a 90° pulse on .sup.1H and X atoms of the RNA sample; (6) recording a chemical shift of X in indirect dimension; (7) applying the 90° pulse on the .sup.1H and X nuclei of the RNA sample; (8) repeating steps 2, 3, and 4; and (9) collecting the .sup.1H signal in direct dimension; where X is selected from the group consisting of .sup.15N and .sup.13C.

A chemical pattern recognition method for evaluating the quality of a traditional Chinese medicine based on medicine effect information, comprising: collecting chemical information of a traditional Chinese medicine sample, obtaining medicine effect information reflecting a clinical therapeutic effect thereof, performing spectrum-effect relationship analysis on the chemical information and the medicine effect information, and obtaining an index significantly related to the medicine effect as a feature chemical index; dividing the traditional Chinese medicine sample into a training set and a test set; using a pattern recognition method to extract a feature variable from samples of the training set by taking the feature chemical index as an input variable; building a pattern recognition model using the feature variable; and substituting feature variable values of samples of the test set into the model, and completing chemical pattern recognition evaluation of the quality of the traditional Chinese medicine. According to the method, chemical reference substances are not needed, the chemical pattern recognition model is built on the basis of the feature chemical index reflecting the medicine effect, the one-sidedness and the subjectivity of the existing standards are overcome, and a traditional Chinese medicine quality evaluation system capable of reflecting both the clinical therapeutic effect and overall chemical composition information is finally formed.

The invention relates to a sample cell for performing DNP-NMR measurements, for interchangeable use in an EPR microwave resonator, with the sample cell comprising a flat sample cavity for holding a liquid sample to be measured, wherein the flat sample cavity extends with a maximum length L and a maximum width W in a sample cavity plane, and extends with a maximum height H perpendicular to the sample cavity plane, with H≤ 1/15*L and H≤ 1/15*W, and an NMR coil wound around the flat sample cavity for generating an RF magnetic field B.sub.2, wherein a coil axis of the NMR coil about which the NMR coil is wound is oriented perpendicular to the sample cavity plane. The invention provides a sample cell which is easy to handle and improves the quality and the reproducibility of DNP-NMR measurements.

The invention relates to a sample cell for performing DNP-NMR measurements, for interchangeable use in an EPR microwave resonator, with the sample cell comprising a flat sample cavity for holding a liquid sample to be measured, wherein the flat sample cavity extends with a maximum length L and a maximum width W in a sample cavity plane, and extends with a maximum height H perpendicular to the sample cavity plane, with H≤ 1/15*L and H≤ 1/15*W, and an NMR coil wound around the flat sample cavity for generating an RF magnetic field B.sub.2, wherein a coil axis of the NMR coil about which the NMR coil is wound is oriented perpendicular to the sample cavity plane. The invention provides a sample cell which is easy to handle and improves the quality and the reproducibility of DNP-NMR measurements.

A method for determining maximum recoverable hydrocarbon (EMR) in a tight reservoir is disclosed. The method includes determining, based on downhole logs, a total measure of hydrocarbon amount within the tight reservoir, determining, by at least attributing fluid loss during core surfacing of the core sample to hydrocarbons, a non-recoverable measure of hydrocarbon amount within a core sample of the tight reservoir, and determining an EMR measure based on the total measure of hydrocarbon amount and the non-recoverable measure of hydrocarbon amount, wherein during the core surfacing pore pressure reduces from a reservoir condition to a surface condition.

The present invention provides methods for high throughput screening and detection of nucleic acids from pathogens, such as SARS CoV-2, using nucleic acid amplification with nanoparticle binding complex formation and MRI or NMR detection. In certain embodiments, the MRI is three-dimensional MRI that simultaneously detects a plurality of amplified nucleic acid-nanoparticle complexes. In certain embodiments, the nucleic acids are amplified by isothermal LAMP techniques. In other embodiments, the nucleic acids are amplified by PCR. Methods of the invention are particularly useful rapid screening of large number of samples during pandemic situations.

Apparatus and methods for the detection of proteins in biological fluids such as urine using a label-free assay is described. Specific proteins are detected by their binding to highly specific capture reagents such as SOMAmers that are attached to the surface of a substrate. Changes to these capture reagents and their local environment upon protein binding modify the behavior of color centers (e.g., fluorescence, ionization state, spin state, etc.) embedded in the substrate beneath the bound capture reagents. These changes can be read out, for example, optically or electrically, for an individual color center or as an average response of many color centers.

A computer implemented method is usable to detect the presence of abnormal tissue through analysis of magnetic resonance relaxation times T1 and T2. The relaxation times T1 and T2 are determined from a data set obtained from a magnetic resonance apparatus. The method includes: loading the data set from at least one tissue into a computing device; determining a region of interest; determining an average value of the free induction decay signal within the region of interest on each of the scans separately; detecting scans with outlier data in each data series; and, if a scan with outlier data is detected, identifying the scan in the data series; determining the relaxation time within the region of interest based on scans from the corresponding data series that are not identified as having outlier data; classifying the tissue as normal or abnormal based on predefined values, which are determined depending on the type of tissue analyzed.