G01N35/10

Automatic sampling of hot phosphoric acid for the determination of chemical element concentrations and control of semiconductor processes

Systems and methods for automatic sampling of a sample for the determination of chemical element concentrations and control of semiconductor processes are described. A system embodiment includes a remote sampling system configured to collect a sample of phosphoric acid at a first location, the remote sampling system including a remote valve having a holding loop coupled thereto; and an analysis system configured for positioning at a second location remote from the first location, the analysis system coupled to the remote valve via a transfer line, the analysis system including an analysis device configured to determine a concentration of one or more components of the sample of phosphoric acid and including a sample pump at the second location configured to introduce the sample from the holding loop into the transfer line for analysis by the analysis device.

Diagnostic test system and method utilizing a closure/sample dispensing mechanism to dispense a sample subvolume for testing
11709175 · 2023-07-25 · ·

A diagnostic test system, including: a diagnostic test assembly and a diagnostic test apparatus to perform a test on a biological or environmental sample; the diagnostic test assembly includes: a sample preparation reservoir to receive the sample into a sample preparation fluid, such that a swab carrying the sample can be used to stir the preparation fluid and to wash the swab; a sample dispensing mechanism for insertion into the sample preparation reservoir; a closure to seal the sample preparation reservoir; at least one diagnostic test reservoir coupled to the sample preparation reservoir; and at least one seal between the sample preparation reservoir and the diagnostic test reservoir to prevent fluid movement between the respective reservoirs; wherein the sample dispensing mechanism is operable to disrupt the seal to allow sample fluid to enter the diagnostic test reservoir from the sample preparation reservoir, and to dispense a predetermined amount of fluid.

Method for operating a laboratory system

A method for operating a laboratory system comprising instruments for processing samples and a control unit connected by a communication network is presented. The method comprises receiving and identifying a biological sample and retrieving an order list from a database. The list comprises a plurality of targets defining one or more processing steps to be carried out on the biological sample by one or more of the laboratory instruments. The method also comprises selecting a workflow strategy and retrieving workflow acceptance criterion corresponding to the workflow strategy. The control unit determines a sample workflow for processing the sample based on the workflow strategy and determines whether the sample workflow satisfies the workflow acceptance criterion. If the sample workflow does not satisfy the workflow acceptance criterion, workflow strategy and the workflow acceptance criterion is refined and the sample workflow is determined again until it satisfies the workflow acceptance criterion.

DISPENSING DEVICE, AUTOMATED ANALYSIS DEVICE, AND DISPENSING METHOD

An object of the present invention is to provide a dispensing device capable of preventing bubbles from jumping out of a nozzle and realizing highly accurate dispensing even though the nozzle is moved at a high speed toward a liquid level and is decelerated and stopped at a high acceleration. The dispensing device according to the present invention starts suction of a liquid in a period from when a nozzle starts to be lowered toward a liquid level of the liquid to when an end portion of the nozzle comes into contact with the liquid level of the liquid and the lowering of the nozzle is stopped (see FIG. 6).

FLUID HANDLING USING RECEPTACLE MARKING FOR NEEDLE POSITIONING
20230003752 · 2023-01-05 ·

A fluid handling unit is configured for handling a fluid contained or to be contained in a receptacle bearing a marking. The unit includes a needle having an elongated shape with an open end and for aspirating the fluid from the receptacle and/or dispensing the fluid into the receptacle. The fluid handling unit further includes a needle drive for positioning the needle with respect to the receptacle, a detection unit for detecting the marking of the receptacle, and a control unit. The control unit is configured for analyzing the detected marking for determining at least one feature that is part of the marking or the marking itself, determining a target position based on the detected at least one feature, and operating the needle drive to position the open end of the needle relative to the determined target position.

AUTOMATIC SAMPLE INJECTION DEVICE
20230236213 · 2023-07-27 · ·

An automatic sample injection device is provided with a vial placement unit (2) configured to place a vial (10) thereon, a sampler (6) provided at a position different from a position of the vial placement unit (2), the sampler being configured to collect a liquid from the vial (10), a conveyance unit (4) provided with a gripper (14) for gripping the vial (10) from above, the conveyance unit being configured to convey the vial (10) between the vial placement unit (2) and the sampler (6), a target position setting unit (22) configured to execute a teaching mode for setting a target position at which the gripper (14) is to be placed when placing the vial (10) at a predetermined position, cause a user to perform positioning of the gripper (14) to a position to be the target position in the teaching mode, and set a position of the gripper (14) positioned by the user as the target position, and a control unit (20) configured to position the gripper (14) at the target position set by the target position setting unit (22) when placing the vial (10) at the predetermined position. The target position setting unit (22) is configured to execute, in the teaching mode, an auxiliary operation for visually assisting positioning of the gripper by the user when causing the user to perform positioning of the gripper (14) to a position to be the target position.

AUTOMATIC SAMPLE INJECTION DEVICE
20230236213 · 2023-07-27 · ·

An automatic sample injection device is provided with a vial placement unit (2) configured to place a vial (10) thereon, a sampler (6) provided at a position different from a position of the vial placement unit (2), the sampler being configured to collect a liquid from the vial (10), a conveyance unit (4) provided with a gripper (14) for gripping the vial (10) from above, the conveyance unit being configured to convey the vial (10) between the vial placement unit (2) and the sampler (6), a target position setting unit (22) configured to execute a teaching mode for setting a target position at which the gripper (14) is to be placed when placing the vial (10) at a predetermined position, cause a user to perform positioning of the gripper (14) to a position to be the target position in the teaching mode, and set a position of the gripper (14) positioned by the user as the target position, and a control unit (20) configured to position the gripper (14) at the target position set by the target position setting unit (22) when placing the vial (10) at the predetermined position. The target position setting unit (22) is configured to execute, in the teaching mode, an auxiliary operation for visually assisting positioning of the gripper by the user when causing the user to perform positioning of the gripper (14) to a position to be the target position.

AUTOMATIC ANALYZER
20230003755 · 2023-01-05 · ·

An automatic analyzer for analyzing samples comprising an immersion tube configured to retrieve a reagent stored in a reagent vessel and a lifting device configured to lift and lower the immersion tube. The lifting device comprises a guide rail on which the immersion tube is moveable between a lowered position, in which the immersion tube is immersed into the reagent vessel, and a lifted position, in which the immersion tube is retracted from the reagent vessel, and at least one biasing member configured to bias the immersion tube towards the lowered position with a predetermined biasing force. The analyzer further comprises a detector configured to detect an identity of the reagent, and a locking device configured to lock the immersion tube in the lifted position and so the immersion tube is moved towards the lowered position only if the reagent identity detected by the detector corresponds to a target identity.

ANTIBODY FLUID DEPOSITS

In one example an apparatus can include a controller communicatively coupled to a droplet dispenser to deposit antibody fluid on a matrix of an immunoblotting array, the controller is to align the droplet dispenser with a protein band included in the matrix, instruct the droplet dispenser to deposit a first antibody fluid on to the protein band of the matrix, and instruct the droplet dispenser to deposit a second antibody fluid on to the protein band of the matrix, adjacent to the first antibody fluid.

Pipetting apparatus, a liquid handling system and a method of controlling pipetting
11565249 · 2023-01-31 · ·

A pipetting apparatus having a pipette tube with a first end provided with an opening for aspirating and/or dispensing of a sample fluid and a second end operationally connected to a pressure generating means. The pipetting apparatus has at least one measuring unit adapted to determine at least one measurement value of the sample fluid based on the aspirating and/or dispensing of the sample fluid and to provide a sample fluid measurement signal representative thereof to an output of the measuring unit. The pipetting apparatus also has a control circuit operationally coupled to the output of the measuring unit and the input of the pressure generating means, the control circuit is configured to control said pressure generating device based on the sample fluid measurement signal.