Sexual dysfunction, including symptoms of vaginal dryness, irritation, and dyspareunia, is a highly prevalent condition with a substantial impact on women's physical, mental, and social well-being. However, the underlying mechanisms responsible for these symptoms are largely unknown, often resulting in inadequate treatment options for patients. Thus, methods to determine interactions between vaginal microbiota, metabolites, and immune proteins in women with or without these symptoms are described herein. The objective of these methods is to improve the understanding of the pathologic mechanisms contributing to poor sexual health.

The present invention relates to a method for assessing whether a subject has Polycystic Ovarian Syndrome (PCOS) or is at risk of developing PCOS, to a method of selecting a patient for therapy of PCOS, to a method for monitoring PCOS progression or for monitoring response to treatment and to a computer-implemented method for assessing a subject with suspected PCOS, by determining the amount or concentration of Meteorin-like protein (METRNL) in a sample of the subject.

The present invention relates to a method for assessing whether a subject has Polycystic Ovarian Syndrome (PCOS) or is at risk of developing PCOS, to a method of selecting a patient for therapy of PCOS, to a method for monitoring PCOS progression or for monitoring response to treatment and to a computer-implemented method for assessing a subject with suspected PCOS, by determining the amount or concentration of Leukotriene A4 Hydrolase (LTA4H) in a sample of the subject.

The present invention relates to a process for determining pregnancy and/or a pregnancy stage of an ungulate from its feces.

The present disclosure describes a method of quantifying analyte levels using gold nanoparticles. The present disclosure also describes a device to quantify analyte levels using gold nanoparticles and image processing of pixels isolated from a single vector. The methods, devices, and systems of the disclosure can be used to quantify analytes such as luteinizing hormone, progesterone, estradiol, or testosterone.