Among other things, a method comprises imaging a sample displaced between a sensor surface and a surface of a microscopy sample chamber to produce an image of at least a part of the sample. The image is produced using lensless optical microscopy, and the sample contains at least blood from a subject. The method also comprises automatically differentiating cells of different types in the image, generating a count of one or more cell types based on the automatic differentiation, and deriving a radiation dose the subject has absorbed based on the count.

A module housing case is described. The modular housing case includes a fiber optic component housing defined as a cavity that is sized to receive a fiber optic connector. Within the cavity is a ferrule guide. The module housing case also has an internal cavity that is at least partially enclosed. Components to assist in magnification may be disposed at least partially within the internal cavity. Finally, the module housing case employs a camera lens alignment feature.

The purpose of this invention is to create a low cost, easy to use, fiber end face and or connector inspection tool component that easily adapts and converts most all mobile communication devices with camera, screen and software capabilities into a microscope. The invention encapsulates and holds firm a fiber connector body and or fiber connector bodies and or ferrule housing or ferrule housings for the purpose of viewing the cleanliness and quality of the fiber end face and or faces. A Fiber end face is the component area and or areas the embodies the fiber core and or fiber cores, fiber ferrule end and or ferrule ends and fiber related end component and or components that are instrumental in the mating with other like components with fiber connector plug end faces and or related optical fiber components for the purpose connectors and splices prior to connecting and or join optical fibers where a connect/disconnect capability is required.

A collection pipette that collects a microscopic object includes a first tube part, a second tube part connected to an end of the first tube part, and a third tube part connected to the other end of the first tube part. The longitudinal direction of the third tube part intersects with the longitudinal direction of the first tube part, and is parallel to the longitudinal direction of the second tube part. For example, the length in the longitudinal direction of the third tube part is shorter than the length in the longitudinal direction of the first tube part.

An optical device includes a first sub-assembly having an input lens for collimating illuminating light and having an optical axis. The first sub-assembly also has an output lens for focusing collimated light received from a sample, the output lens having an optical axis which is offset and substantially parallel with the optical axis of the input lens, and further includes a first support piece which houses and supports the input lens and the output lens. The optical device also includes a second sub-assembly having an input filter for filtering the collimated illuminating light, an output filter for filtering the collimated light received from the sample, and a second support piece which houses and supports the input filter and the output filter. The first and second support pieces are joined together by a liquid-tight joint.

Disclosed is a lens-attached tissue cell pressurization device that is selectively coupled to an objective lens to perform pressurization in an optical device configured measure a cell tissue using the objective lens, the lens-attached tissue cell pressurization device including: a body extending in a lengthwise direction of the objective lens such that at least a portion of the objective lens is inserted into the body and having a connector selectively fixed to the objective lens; and an indenter provided at a lower end of the body, having a penetration part formed at a center of the indenter, and pressurizing the cell tissue by a change in a relative location of the objective lens and the cell tissue.

A system and method for using a microscope to at least haptically observe a specimen in a fluid is provided. In one embodiment of the present invention, an audio frequency modulation sensing (AFMS) device is used to convert an optical signal from the specimen into an electrical signal. A haptic feedback device is then used to convert the electrical signal in at least vibrations, thereby providing a user with haptic feedback associated with the optical signal from the specimen. In another embodiment, a second electrical signal can be provided to a second haptic feedback (e.g., shaker, piezo electric, electric current inducing, etc.) device in the fluid, thereby allowing for bidirectional haptic feedback between the user and the specimen. In other embodiments, aural data can be extracted from the electrical signal and presented to the user either alone in in synchronization with video data (e.g., from a video camera).

An optical inspection apparatus includes a stage that supports a target substrate, the target substrate including a plurality of light emitting elements, a jig that applies an electrical signal to the target substrate, the jig including a regulation resistor, a microscope that generates magnified image data of the target substrate, a camera that captures the magnified image data to generate a color image of the target substrate, and an optical measurement unit that captures the magnified image data of the target substrate to generate a spectrum image and measure optical characteristics of the target substrate.

Provided herein are systems and methods for simultaneous imaging and stimulation using a microscope system. The microscope system can have a relatively small size compared to an average microscope system. The microscope can comprise in part an imaging light source and a stimulation light source. Light from the imaging light source and the stimulation light source can be spectrally separated to reduce cross talk between the stimulation light and the imaging light.

A microstructured optical fiber having a length and a longitudinal axis along its length, the finer including a core region capable of guiding light along the longitudinal axis and a cladding region which surrounds the core region, the cladding region comprising a cladding background material and a plurality of cladding features within the cladding background material, the cladding features being arranged around the core region, wherein the cladding region comprises an inner cladding region comprising an innermost ring of cladding features and an outer cladding region comprises outer cladding rings of outer cladding features, the innermost ring consisting of those cladding features being closest to the core region, wherein the rings of cladding features each comprise bridges of cladding background material separating adjacent features of the ring, wherein the bridges of the innermost ring have an average minimum width (w1), the minimum width of a bridge of a ring being the shortest distance between two adjacent features of the ring; and wherein at least one outer cladding ring has an average minimum width (w2) of bridges that is larger than the average minimum width (w1) of the bridges of the innermost ring. Also described are a cascade optical fiber with at least one fiber as described, as well as a source of supercontinuum radiation.