A device for purifying and formulating a radiopharmaceutical compound includes an automated purification subsystem that automates the loading of a sample into a sample loop for downstream purification via HPLC. A column selector valve is provided to select from one of a plurality of columns. Fractions can be collected as well as the desired product. The device includes an automated formulation subsystem that first sends the product to a dilution reservoir prior to being pneumatically pushed onto a solid phase extraction (SPE) cartridge. Automated rinse, elution, and reconstitution are also performed with the automated formulation subsystem. The device may be directly coupled to the output of an automated radiosynthesizer.

The invention relates to a portable containment device for manipulating organic and/or chemical substances, which includes: a transporting case including two half-cases (2, 3) connected by a hinged structure (4) such as to be movable between a closed position (F), in which the half-cases (2, 3) are against one another and define a stowing space for at least the hinged structure (4), and an open position (O), in which the half-cases (2, 3) are spaced apart from one another by being maintained vertical by the hinged structure (4) and in which the half-cases (2, 3) and the hinged structure (4) form a supporting structure for a flexible containment enclosure (20); and a plastic, removable and flexible containment enclosure (20) that is at least partially transparent, for forming a generally parallelepiped foldable isolation chamber provided with means (31, 32) for accessing the inside of the enclosure and with means (21) for attachment to the supporting structure. The containment enclosure (20) is collapsible inside the transporting case in the closed position (F). The invention also relates to a removable, flexible enclosure for such a device.

A containment system and method for creating a confined space around a portion of a piping circuit, and for maintaining the confined space at a designated pressure with a pressurized blanketing gas. The confined spaced with its controlled environment protects against process upsets or icing when insulation is removed from sections in extreme temperature services. The containment system includes a shroud assembly that is made up of a cover configured into a tubular shape, and end plates on axial ends of the cover that mount onto the piping. Support rings are set within the cover that also mount to the pipe, and which provide radial support for the cover along the span between the end plates. Ports are formed through a sidewall of the cover that provide operations personnel access to the piping. Lines carrying the pressurized blanketing gas connect to inlets formed in the cover sidewall.

An airtight apparatus in which an airtight box (30) for measurement is combined with a glove box (20) is provided. The airtight box (30) for measurement includes a hollow housing (31), and a sample stage (34) having a sample loading portion. The sample stage (34) is transported by a transport stage (35) installed in the housing (31). The housing (31) is provided with a measurement window (40) for measuring a sample loaded on the sample stage (34) from the outside by a measurement apparatus (10).

An airtight apparatus in which an airtight box (30) for measurement is combined with a glove box (20) is provided. The airtight box (30) for measurement includes a hollow housing (31), and a sample stage (34) having a sample loading portion. The sample stage (34) is transported by a transport stage (35) installed in the housing (31). The housing (31) is provided with a measurement window (40) for measuring a sample loaded on the sample stage (34) from the outside by a measurement apparatus (10).

A decontamination assembly (1) for pharmaceutical applications, comprising an isolator (2) having a manipulator chamber (3) and a plenum chamber (4) which is disposed above the manipulator chamber (3) and which can be supplied with an air flow (9) via at least one circulation fan (7) disposed in a circulating-air generation chamber, a membrane (5) for generating a laminar air flow (11) in the manipulator chamber (3) during a working operating state being disposed between the plenum chamber (4) and the manipulator chamber (3), the manipulator chamber (3) being connected to the circulating-air generation chamber (6) in an air-conducting manner via a return-air channel (12), further comprising ultrafine distributing means (19), for producing a decontaminant/air mixture based on a liquid decontaminant stock, a stock of H.sub.2O.sub.2, the ultrafine distributing means (19) being connected to the plenum chamber (4) via at least one plenum supply line (25) leading into the plenum chamber (4) so as to directly supply the plenum chamber (4) with the decontaminant/air mixture when in a decontamination operating state, wherein the ultrafine distributing means (19) are connected directly to the manipulator chamber (3) via at least one manipulator supply line (27) so as to directly supply the manipulator chamber (3) with the decontaminant/air mixture when in the decontamination operating state.

A decontamination assembly (1) for pharmaceutical applications, comprising an isolator (2) having a manipulator chamber (3) and a plenum chamber (4) which is disposed above the manipulator chamber (3) and which can be supplied with an air flow (9) via at least one circulation fan (7) disposed in a circulating-air generation chamber, a membrane (5) for generating a laminar air flow (11) in the manipulator chamber (3) during a working operating state being disposed between the plenum chamber (4) and the manipulator chamber (3), the manipulator chamber (3) being connected to the circulating-air generation chamber (6) in an air-conducting manner via a return-air channel (12), further comprising ultrafine distributing means (19), for producing a decontaminant/air mixture based on a liquid decontaminant stock, a stock of H.sub.2O.sub.2, the ultrafine distributing means (19) being connected to the plenum chamber (4) via at least one plenum supply line (25) leading into the plenum chamber (4) so as to directly supply the plenum chamber (4) with the decontaminant/air mixture when in a decontamination operating state, wherein the ultrafine distributing means (19) are connected directly to the manipulator chamber (3) via at least one manipulator supply line (27) so as to directly supply the manipulator chamber (3) with the decontaminant/air mixture when in the decontamination operating state.

Disclosed is a calibrator device designed to measure the activity of a radio element, including: an ionization chamber, intended to receive the radio element; and electronic/computer system for controlling the operation of the calibrator device. The electronic/computer system includes voice control, which include: at least one microphone capable of capturing a voice instruction emitted by the operator; a recognition module designed to convert the voice instruction into a request that can be executed by the electronic/computer system; and a control module designed to control the execution of the request by the electronic/computer system.

Disclosed is a calibrator device designed to measure the activity of a radio element, including: an ionization chamber, intended to receive the radio element; and electronic/computer system for controlling the operation of the calibrator device. The electronic/computer system includes voice control, which include: at least one microphone capable of capturing a voice instruction emitted by the operator; a recognition module designed to convert the voice instruction into a request that can be executed by the electronic/computer system; and a control module designed to control the execution of the request by the electronic/computer system.

A transfer system for a sealed enclosure, the sealed enclosure defining a first closed volume and having at least one device for sealed connection to a second closed volume, the transfer system being intended to be disposed in the enclosure and to be fastened to a wall of the latter, the transfer system including a chute and a hinge device fastened inside the enclosure, the hinge device including two arms and three pivot hinges and three motors.