G01N2015/1027

Handling Obstructions and Transmission Element Contamination for Self-Mixing Particulate Matter Sensors
20200318945 · 2020-10-08 ·

A portable electronic device is operable in a particulate matter concentration mode where the portable electronic device uses a self-mixing interferometry sensor to emit a beam of coherent light from an optical resonant cavity, receive a reflection or backscatter of the beam into the optical resonant cavity, produce a self-mixing signal resulting from a reflection or backscatter of the beam of coherent light, and determine a particle velocity and/or particulate matter concentration using the self-mixing signal. The portable electronic device is also operable in an absolute distance mode where the portable electronic device determines whether or not an absolute distance determined using the self-mixing signal is outside or within a particulate sensing volume associated with the beam of coherent light. If not, the portable electronic device may determine a contamination and/or obstruction is present that may result in inaccurate particle velocity and/or particulate matter concentration determination.

Mobile terminal comprising a dust sensor for sensing scattered light by dust particles and operation method of the same

A mobile terminal and an operation method thereof are disclosed. A mobile terminal according to an embodiment of the present disclosure may include a display; a front window disposed at a front of the mobile terminal; an inner frame formed with a hole configured to allow light to pass through from the front window; and a dust sensor comprising a light emitting portion and a light receiving portion, wherein the light emitting portion is disposed adjacent to the inner frame and configured to emit light through the hole, and wherein the light receiving portion is configured to generate a signal based on light sensed through the hole that is emitted by the light emitting portion and scattered by dust particles.

METHOD OF DETECTING CANCER CELLS USING MICRO-VIBRATION
20200300747 · 2020-09-24 ·

The present invention relates to a method for cancer cell separation, and more specifically, relates to a method for cancer cell separation using micro-vibration.

CELL CHEMOTAXIS ASSAYS
20200292528 · 2020-09-17 ·

A device includes an input chamber, an attractant chamber, a migration channel arranged in fluid communication between an outlet of the input chamber and inlet of the attractant chamber, a baffle arranged in fluid communication between the outlet of the input chamber and the migration channel or within the migration channel, and an exit channel in fluid communication with the migration channel at a point beyond the baffle and before the migration channel enters the inlet of the attractant chamber. The baffle is configured to inhibit movement of a first type of cell through the baffle to a greater extent than the baffle inhibits movement of a second type of cell through the baffle.

Apparatus and method for measuring microscopic object velocities in flow
10753857 · 2020-08-25 · ·

A method for measuring microscopic object velocities in fluid flow in a capillary tube including scanning a microscope focal plane through a fluid filled space for objects, where the scanning follows an interrupted repeating pattern having sub-patterns where the sub-patterns position the microscope focus plane beginning at a selected focus position at a first time and ending at the selected focus position at a later second time. A sensor registers images in image frames during the scanning. A first object image is registered in a first image frame at the selected focus position and a second object image is registered in a second image frame at the selected focus position. The object in the first object image and the second object image are identified as the same object. A processor determines a velocity for the identified object.

Laser sensor for particle size detection

The invention describes a laser sensor module (100) for particle size detection. The laser sensor module (100) comprises at least one first laser (110), at least one first detector (120), at least one electrical driver (130) and at least one evaluator (140). The first laser (110) is adapted to emit first laser light in reaction to signals provided by the at least one driver (130). The at least one first detector (120) is adapted to determine a first self-mixing interference signal (30) of an optical wave within a first laser cavity of the first laser (110). The first self-mixing interference signal (30) is caused by first reflected laser light reentering the first laser cavity, the first reflected laser light being reflected by a particle receiving at least a part of the first laser light. The evaluator (140) is adapted to determine a size of the particle by determining a first relative distance between the particle and the first laser (110) by means of the first self-mixing interference signal (30) and by determining a first amplitude information by means of the first self-mixing interference signal (30). The invention is further related to a corresponding method of determining a particle size.

Optimised ion mobility separation timescales for targeted ions

An analytical device for analysing ions is provided comprising a separator 2 for separating ions according to a physico-chemical property and an interface 3 comprising one or more ion guides. A quadrupole rod set mass filter 4 is arranged downstream of the interface 3. A control system is arranged and adapted: (i) to transmit a first group of ions which emerges from the separator 2 through the interface 3 with a first transit time t1; and (ii) to transmit a second group of ions which subsequently emerges from the separator 2 through the interface 3 with a second different transit time t2.

SYSTEM AND METHOD FOR PARTICLES MEASUREMENT

An optical system for particle size and concentration analysis, includes: at least one laser that produces an illuminating beam; a focusing lens that focuses the illuminating beam on particles that move relative to the illuminating beam at known or pre-defined angles to the illuminating beam through the focal region of the focusing lens; and at least two forward-looking detectors, that detect interactions of particles with the illuminating beam in the focal region of the focusing lens. The focusing lens is a cylindrical lens that forms a focal region that is: (i) narrow in the direction of relative motion between the particles and the illuminating beam, and (ii) wide in a direction perpendicular to a plane defined by an optical axis of the system and the direction of relative motion between the particles and the illuminating beam. Each of the two forward-looking detectors is comprised of two segmented linear arrays of detectors.

Device and method for flow and bead speed characterization in microfluidic devices

Method, apparatus, and computer program product for a microfluidic channel having a cover opposite its bottom, the cover allowing visual inspection inside the channel, and having electrodes with patterned planar conducting materials, integrated onto its bottom. Using the planar conducting materials, once a fluid sample with suspended microparticles is applied into the channel, highly localized modulated electric field distributions are generated inside the channel and the fluid sample. This generated field causes inducing of dielectrophoretic (DEP) forces such that the DEP forces gradually increase along the length of the channel occupied by the electrodes. These DEP forces counteract the hydrodynamic drag of the flow acting on the particles suspended in the fluid. Because of the induced forces, micro/nano-particles in the fluid sample are deflected at locations in the microchannel that are a function of the particles velocity and this effect is captured by an image sensing device.

Occupancy grid object determining devices

An occupancy grid object determining device is provided, which may include a grid generator configured to generate an occupancy grid of a predetermined region, the occupancy grid including a plurality of grid cells and at least some of the grid cells having been assigned an information about the occupancy of the region represented by the respective grid cell, a determiner configured to determine at least one object in the occupancy grid wherein the at least one object includes a plurality of grid cells, and a remover configured to remove occupancy information from at least one grid cell of the plurality of grid cells of the determined object.