A polarimeter for measuring chirality of a material comprising an optical ring cavity comprising a plurality of reflective elements configured to promote bi-directional propagation of a laser beam within the cavity, a laser-emitting device configured to introduce a first input beam and a second input beam into the cavity, a Faraday rotator, a phase compensator, an acousto-optic modulator configured to shift the frequency of the first output beam, an optical recombination device configured to recombine shifted and unshifted output beams, and first and second detectors configured to receive the recombined beams, wherein the plurality of reflective elements, Faraday rotator, and phase compensator are configured such that light from the first and second input beams passes through a chiral material located within the cavity a sufficient number of times for a measurement of optical rotary dispersion and circular dichroism of light transmitted through the material to be obtained at the detectors.

The present disclosure relates to a composition for cell imaging, including a fluorescent probe compound, and a method of cell-material imaging using the same.

A circular dichroism spectrometer which comprises a metasurface. The metasurface has a plurality of anisotropic antennas configured to simultaneously spatially separate LCP and RCP spectral components from an incoming light beam. An optical detector array is included which detects the LCP and RCP spectral components. A transparent medium is situated between the metasurface and the optical detector array.

A circular dichroism spectrometer which comprises a metasurface. The metasurface has a plurality of anisotropic antennas configured to simultaneously spatially separate LCP and RCP spectral components from an incoming light beam. An optical detector array is included which detects the LCP and RCP spectral components. A transparent medium is situated between the metasurface and the optical detector array.

A vibrational circular dichroism (VCD) spectroscopy method and apparatus that can significantly reduce the measurement time needed to acquire a differential absorption spectrum compared to known approaches. A dual-comb is generated by superimposing the outputs from two quantum cascade laser sources, thus providing a third comb interferogram with beat frequencies higher than the polarization modulation frequency. Consequently, for each of the left and right circularly polarized light, the measurement signal measures transmission through the sample across the full wavelength range of interest during each period of the polarization modulation. A complete vibrational spectrum is thus acquired in each modulation of a polarization modulator, instead of only acquiring data for a single wavelength during each modulation of the polarization, as in dispersive or tunable laser VCD, or only a single Fourier component of the spectrum, as in Fourier transform VCD.

A vibrational circular dichroism (VCD) spectroscopy method and apparatus that can significantly reduce the measurement time needed to acquire a differential absorption spectrum compared to known approaches. A dual-comb is generated by superimposing the outputs from two quantum cascade laser sources, thus providing a third comb interferogram with beat frequencies higher than the polarization modulation frequency. Consequently, for each of the left and right circularly polarized light, the measurement signal measures transmission through the sample across the full wavelength range of interest during each period of the polarization modulation. A complete vibrational spectrum is thus acquired in each modulation of a polarization modulator, instead of only acquiring data for a single wavelength during each modulation of the polarization, as in dispersive or tunable laser VCD, or only a single Fourier component of the spectrum, as in Fourier transform VCD.

A solid-state imaging device and an imaging apparatus capable of realizing further miniaturization of an imaging apparatus and further improvement of light use efficiency are to be provided. The present technology provides a solid-state imaging device that includes a plurality of pixels arranged one- or two-dimensionally, in which each pixel includes at least a light receiving unit, and the light receiving unit included in at least some of the plurality of pixels have circularly polarized dichroism. The present technology also provides an imaging apparatus that includes at least: the solid-state imaging device; and a signal processing unit that generates an image capturing only specific circularly polarized light, on the basis of a signal obtained from at least one of the pixels of the solid-state imaging device.

A circular dichroism measurement device includes: a sample part having a sample; a PEM that modulates a polarization state of an incoming light to the sample part or an outgoing light from the sample part; a photo detector that detects a change in a light intensity of the outgoing light from the sample part; an amplifier that amplifies a detection signal from the photo detector; an A/D converter that converts the detection signal amplified by the amplifier to a digital signal; and a digital processing device that executes a signal processing to the digital signal from the A/D converter to acquire a measurement value of circular dichroism of the sample. The A/D converter is configured to convert the detection signal, that is amplified in a state of containing the AC component and the DC component of the light intensity that changes with the same frequency as the modulation frequency of PEM.

A circular dichroism measurement device includes: a sample part having a sample; a PEM that modulates a polarization state of an incoming light to the sample part or an outgoing light from the sample part; a photo detector that detects a change in a light intensity of the outgoing light from the sample part; an amplifier that amplifies a detection signal from the photo detector; an A/D converter that converts the detection signal amplified by the amplifier to a digital signal; and a digital processing device that executes a signal processing to the digital signal from the A/D converter to acquire a measurement value of circular dichroism of the sample. The A/D converter is configured to convert the detection signal, that is amplified in a state of containing the AC component and the DC component of the light intensity that changes with the same frequency as the modulation frequency of PEM.

A spectroscopic analysis device includes a light source configured to emit light including a plurality of wavelength components, a polarizer configured to convert the light emitted from the light source to a light of linearly polarized light to be radiated to a sample, a polarizing diffraction element configured to diffract and spectrally disperse a first polarization component included in the light having passed through the sample in a first direction, the polarizing diffraction element being configured to diffract and spectrally disperse a second polarization component included in the light in a second direction different from the first direction, a prism which is disposed on an exit side of the polarizing diffraction element and which has a first exit surface crossing the first direction and a second exit surface crossing the second direction, and in which angles of the first exit surface and the second exit surface with respect to a reference plane including the first direction and the second direction are different, an imaging element configured to capture an image of the first polarization component emitted from the first exit surface of the prism and an image of the second polarization component emitted from the second exit surface, and a processor configured to analyze the sample based on an imaging result of the imaging element.