An analyte testing system for quantifying the presence of an analyte in a specimen by immunochromatography. The system comprises a camera test card, depicting a test cassette (10) with an immunochromatography and a handheld processor device (16) comprising a digital camera (16a), a source of light (16b) and a processor (16c), which software and hardware (16c) are configured to make a pose estimation of camera and object and the measures of light in the region of interest of the immunochromatography. The system allows an automatic camera calibration and certification as a scanner for use in point-of-care diagnostics.

A system for prompt virus infection carriers detection/screening using THz spectroscopy, which comprises a micro/nano-antennas array implemented as an antenna chip of predetermined shape and size, that has the maximum aspect ratio of the capacitor gap being sensitive to both P and S polarization, the array consisting of a plurality of printed micro-antenna elements, each of which having an equivalent inductor L of printed inductors and an equivalent capacitor C defined by gaps between printed contacts the length of the capacitor and the dielectric constant of a filler being between the printed contacts, to thereby determine a resonant frequency of the antenna element, the gaps are formed essentially along the cross diagonals of the each antenna element, thereby obtaining maximal aspect-ratio between the length of the capacitor and the gap width, that maximizes and sharpen the resonance effect of the each micro-antenna element; at least one capsule for holding the chip with the antennas array in a fixed position, preferably at the center, the at least one capsule being at least partially transparent to THz radiation range; means for applying material containing samples of viruses/exhaled biological ingredients to be detected that are exhaled into the gaps, for altering the dielectric constant of the filler and the resonance frequency; a THz spectrometer for scanning the samples and detecting shifts in the resonance frequency induced by the presence of the exhaled viruses/biological ingredients; at least one processor for processing the detected shifts in the resonance frequency and associating different shifts with different types of viruses/biological ingredients. The size of the array is matched to the beam size of the spectrometer, such that the entire radiation collimated beam will be captured by the antennas array, thereby maximizing the signal to noise ratio and the dynamic range.

An inspection device includes a small shutter in an opening of an inspection chamber, and a large shutter behind the small shutter. The small shutter has a closed state, an inward-open state, and an outward-open state. The small shutter in the inward-open or outward-open state is pushed by a workpiece and pivots inward in or outward from the inspection chamber. The large shutter has a light-shielding state, a driven state, and a stationary state. The large shutter in the light-shielding state overlaps the small shutter in the closed state and closes a clearance between the opening and the small shutter. The large shutter in the driven state is pushed by the small shutter in the inward-open state and pivots with the small shutter. The large shutter in the stationary state is separate from the small shutter in the outward-open state and at a same position as in the light-shielding state.

A testing apparatus for performing an assay, the testing apparatus comprising: a receptacle (2) containing a reagent, the reagent being reactive to an applied test sample by developing a colour or pattern variation; a portable device (1), e.g. a mobile phone or a laptop, comprising a processor and an image capture device (3), wherein the processor is configured to process data captured by the image capture device and output a test result for the applied test sample.

A portable point of care device (1) for use in testing a biological sample, the device comprising: a sample collection member (4), a test cartridge (2), and a reader (220).

An all-in-one handheld machine for testing drugs in hairs comprises a handheld shell, a control mechanism, a fluorescent immune reagent card test mechanism, an identity recognition mechanism, and a control instruction input unit communicatively connected to the control mechanism are provided in the shell; a shell surface is provided with a reagent card inlet that corresponds to a reagent card socket of the test mechanism; the control mechanism is controllably connected to the test mechanism and the identity recognition mechanism, and is communicatively connected with a communication unit; the control mechanism, the test mechanism and the identity recognition mechanism are all electrically connected to a power supply module. The invention can achieve the functions of identity card reading and wireless data transmission, and the test for trace drug residues in hairs, thereby meeting the requirements for rapidity, portability and accuracy of an on-site test.

Disclosed is a device including a substrate having a plurality of detection areas to receive at least a portion of a sample having an analyte or suspected of having an analyte and at least one reference marker adjacent to at least one of the detection areas, wherein each of the detection areas detects a specific analyte and the at least one reference marker defines a scale mark, a shape mark, a color mark, or a combination thereof. Also disclosed is an imaging system and method for using the device and imaging system.

The invention encompasses a real time, point of care, diagnostic system, including a lateral flow test cassette, a data reader, and an application for processing test results and methods of diagnosis of a disease or virus.

The present disclosure relates to devices, apparatus and methods of improving the accuracy of an image-based assay. One aspect of the present invention is to sandwich a sample between two plates and add reference marks in the sample areas of the plates, with at least one of the geometric and/optical properties of the reference marks being predetermined and known, and taking images of the sample with the reference marks, and applying a machine learning model in the analysis of the image-based assay.

Systems and methods to analyzes images of lateral flow assays are disclosed herein. An example image analysis system includes processor circuitry to (a) determine whether a format of an image of a lateral flow assay device satisfies a format threshold, (b) in response to determining the format of the image satisfies the format threshold, determine whether the lateral flow assay device in the image is authentic, (c) in response to determining the lateral flow assay device is authentic, determine whether a position of the lateral flow assay device in the image satisfies a position threshold, (d) in response to determining the position of the lateral flow assay device satisfies the position threshold, analyze the image to determine the result of the diagnostic test, and (e) abort the sequence of the operations during performance of the sequence of operations at the time any one of operations fails.