Patent classifications
G01N25/04
METHOD FOR CHARACTERIZING MELTING TRANSITION AND CRYSTALLIZATION IN A SEMICRYSTALLINE POLYMER
A method for characterizing a melting transition in a semicrystalline polymer is disclosed. The method includes incorporating a fluorophore into the semicrystalline polymer, changing a temperature of the semicrystalline polymer to vary across a range of temperatures comprising a plurality of temperatures, and capturing an emission spectrum of the incorporated fluorophore at each temperature of the plurality of temperatures. The method also includes integrating each emission spectrum to determine a temperature-dependent integrated fluorescence intensity for the semicrystalline polymer, numerically differentiating the temperature-dependent integrated fluorescence intensity, and characterizing the melting transition of the semicrystalline polymer by identifying a stepwise change in value of the differentiated intensity. The semicrystalline polymer may be a thermoplastic. Incorporating the fluorophore into the semicrystalline polymer may include physically doping the semicrystalline polymer with the fluorophore or covalently labeling the semicrystalline polymer with the fluorophore.
METHOD FOR CHARACTERIZING MELTING TRANSITION AND CRYSTALLIZATION IN A SEMICRYSTALLINE POLYMER
A method for characterizing a melting transition in a semicrystalline polymer is disclosed. The method includes incorporating a fluorophore into the semicrystalline polymer, changing a temperature of the semicrystalline polymer to vary across a range of temperatures comprising a plurality of temperatures, and capturing an emission spectrum of the incorporated fluorophore at each temperature of the plurality of temperatures. The method also includes integrating each emission spectrum to determine a temperature-dependent integrated fluorescence intensity for the semicrystalline polymer, numerically differentiating the temperature-dependent integrated fluorescence intensity, and characterizing the melting transition of the semicrystalline polymer by identifying a stepwise change in value of the differentiated intensity. The semicrystalline polymer may be a thermoplastic. Incorporating the fluorophore into the semicrystalline polymer may include physically doping the semicrystalline polymer with the fluorophore or covalently labeling the semicrystalline polymer with the fluorophore.
SYSTEM AND METHOD FOR MELTING CURVE NORMALIZATION
The present invention relates to methods for the analysis of nucleic acids present in biological samples, and more specifically to normalize a high resolution melt curve to assist in the identification of one or more properties of the nucleic acids. The present invention provides methods and systems that incorporate a background identification algorithm according to invention principles using raw melt curve data to identify reactions that are unrelated actual DNA melt reactions. Furthermore, a web-based application for analyzing experimental data is provided. The raw experimental data obtained from a variety of instruments is processed and analyzed on a server and presented to a user through a user interface (UI).
SYSTEM AND METHOD FOR MELTING CURVE NORMALIZATION
The present invention relates to methods for the analysis of nucleic acids present in biological samples, and more specifically to normalize a high resolution melt curve to assist in the identification of one or more properties of the nucleic acids. The present invention provides methods and systems that incorporate a background identification algorithm according to invention principles using raw melt curve data to identify reactions that are unrelated actual DNA melt reactions. Furthermore, a web-based application for analyzing experimental data is provided. The raw experimental data obtained from a variety of instruments is processed and analyzed on a server and presented to a user through a user interface (UI).
Method and apparatus for determining an icing condition status of an environment
The method includes receiving a value of a quantity of heat applied to at least a portion of a structure, said structure having a sensor surface exposed to the environment, receiving a temperature measurement of the sensor surface, receiving a wind speed measurement of the environment, receiving an ambient temperature measurement of the environment, determining a heat transfer projection of the sensor area using at least the wind speed measurement, the ambient temperature measurement, and one of the value of a quantity of heat and a target temperature of the sensor surface; comparing the heat transfer projection to an associated heat transfer value, and generating a signal indicating the icing condition status based on the comparison.
Method and apparatus for determining an icing condition status of an environment
The method includes receiving a value of a quantity of heat applied to at least a portion of a structure, said structure having a sensor surface exposed to the environment, receiving a temperature measurement of the sensor surface, receiving a wind speed measurement of the environment, receiving an ambient temperature measurement of the environment, determining a heat transfer projection of the sensor area using at least the wind speed measurement, the ambient temperature measurement, and one of the value of a quantity of heat and a target temperature of the sensor surface; comparing the heat transfer projection to an associated heat transfer value, and generating a signal indicating the icing condition status based on the comparison.
IN SITU PROBE FOR MEASUREMENT OF LIQUIDUS TEMPERATURE IN A MOLTEN SALT REACTOR
A method for in-situ measuring of a liquidus temperature of a supply of the molten salt, includes withdrawing a sample of the molten salt from the supply, placing it into a sample container, and cooling the sample of the molten salt from a first temperature above the liquidus temperature of the molten salt to a second temperature at which at least a portion of the sample of the molten salt solidifies. The method includes taking a plurality of temperature measurements of the sample of the molten salt during cooling of the sample and determining the liquidus temperature of the molten salt from the measurements. The sample of the molten salt is heated from the second temperature to the first temperature and returned to the supply of the molten salt.
MACHINE FOR TESTING THERMAL RESISTANCE OF PLASTIC MATERIALS, IN PARTICULAR THERMOPLASTIC POLYMERS
Machine for testing thermal resistance of plastic materials, comprising a tank configured, in use, to be filled for example with a heat-transfer fluid; a heating coil for heating the heat-transfer fluid; a temperature sensor generating a temperature signal of the heat-transfer fluid; and a control unit calculating a degradation index of the heat-transfer fluid on the basis of the temperature signal. In particular, the degradation index is calculated by determining the temperature range associated with the temperature signal, updating the corresponding partial heating time, and calculating the weighted sum of the partial heating times previously saved in memory and pertaining to different temperature ranges. Upon reaching one or more thresholds, signals are generated which indicate the need to replace the heat-transfer fluid.
LOW-FRICTION SEALING DEVICE AND ROLLING BEARING EQUIPPED THEREWITH
A sealing device for insertion between a first and a second bearing part. The device including a rotating first shield, a stationary second shield, and an elastomeric sealing element having a first and a second sealing lip. The first shield includes a peripheral section having a first and a second axially extending sleeve portion connected by a first radially extending flange portion. The second shield including a support section for the lips, having an intermediate frustoconical portion that connects a second flange portion of the peripheral section to a mounting section of the second shield. The intermediate portion is positioned axially at a step formed by the first flange portion and by the first sleeve portion. The mounting section is arranged partially inside the second sleeve portion to form an axially directed labyrinth seal that is in metal-to-metal contact with the second bearing.
HOT TESTING MACHINE, IN PARTICULAR OF THERMOPLASTIC POLYMERS, AND ASSOCIATED METHOD
Machine and method for hot testing test pieces made of a thermoplastic polymer, in which the test pieces are immersed in a tank full of a heat transfer liquid which is heated; a fan generates, immediately above the tank, an air flow to carry away volatile substances emitted by the tank and the air flow is made to pass through a filtering cartridge housed removably inside a first chamber delimited by a casing, which is provided with an inlet opening, that faces towards the tank and is arranged flush with or immediately above an upper perimetral edge of the tank; the air flow is made to pass sequentially through at least three filtering elements, which are arranged hydraulically in series, including: a pre-filter; at least one activated carbon filter; and a HEPA filter; an hour counter signals when the time has come to replace the filtering cartridge.