The present disclosure refers to a sensor assembly for an IVD analyzer, the sensor comprising two opposite substrates with at least one fluidic conduit for receiving a sample. The electrodes of different types of electrochemical sensors are arranged on the two opposite substrates facing the at least one fluidic conduit for coming in contact with the sample and determining sample parameters, wherein the counter electrodes and the reference electrodes are formed on one substrate and the working electrodes are formed on the opposite substrate. This achieves optimal sensor-working conditions in terms of a homogeneous and symmetrical electric field density and enables a sensor assembly with simpler geometry and smaller size.

The present disclosure refers to a sensor device, a method of operating the sensor device and an IVD analyzer for receiving the sensor device for determining chemical and/or physical characteristics of a fluid. The sensor device comprises at least two fluidic conduits for repeatedly receiving fluids, each fluidic conduit comprising at least one sensory element arranged such as to come in contact with a fluid in the respective fluidic conduit. In particular, the fluidic conduits comprise different sensory elements, respectively, wherein the sensory elements are separated in the respective fluidic conduits according to compatibility or susceptibility to deterioration or operating temperature. Alternately, the fluidic conduits comprise at least in part the same sensory elements, wherein the sensor device is operated in a primary operating mode and in response to a trigger event, switches to an extended operating mode.

The present disclosure provides a biological detection device, a biological chip, a microelectrode structure, and a manufacturing method of the microelectrode structure. The microelectrode structure can include a first insulating layer, a protrusion, and an electrode layer. The protrusion is disposed on the first insulating layer. The electrode layer conformally covers the first insulating layer and the protrusion. The present disclosure can improve the detection accuracy.

An electrochemical sensor array for detecting analytes in water, including a frame; a plurality of sensor electrodes each mounted to the frame, including a free chlorine working electrode including a gold thin film and having a free chlorine sensing surface to be exposed to the water; and a reference electrode including a silver thin film and a silver and silver chloride layer and having a reference sensing surface to be exposed to the water. A method of manufacturing an electrochemical sensor array for detecting analytes in water, including forming a free chlorine electrode, including forming a gold thin film on a first base layer; forming a reference electrode, including forming a silver thin film on a second base layer and applying a silver and silver chloride paste to a portion of the silver thin film; and arranging the free chlorine electrode and the reference electrode on a common frame.

Disclosed is an integrated biochemical sensor including a reference electrode, a plurality of working electrodes each having different artificial lipid membranes, and partition layers for electrically insulating the reference electrode and each of the working electrodes.

A urine analyzer device, configured to be installed in a toilet bowl, to be used several times, the device comprising a holder member, to attach the device to the rim of the toilet bowl, an electronic unit, enclosed in a housing, a urine reception area, with at least one electro-chemical sensor, configured to measure a quantity of at least one substance contained in urine, such as physiological compound or chemical component, a wireless coupler to send resulting data to a remote computing device, wherein the electro-chemical sensor comprises at least a ion selective Field Effect Transistor (ISFET), configured to sense levels of one or more physiological ions, thereby providing a urine analyzer device, readily available at home, simply installed in a toilet bowl, and that can be used several times subsequently.

A urine analyzer device, configured to be installed in a toilet bowl, to be used several times, the device comprising a holder member, to attach the device to the rim of the toilet bowl, an electronic unit, enclosed in a housing, a urine reception area, with at least one electro-chemical sensor, configured to measure a quantity of at least one substance contained in urine, such as physiological compound or chemical component, a wireless coupler to send resulting data to a remote computing device, wherein the electro-chemical sensor comprises at least a ion selective Field Effect Transistor (ISFET), configured to sense levels of one or more physiological ions, thereby providing a urine analyzer device, readily available at home, simply installed in a toilet bowl, and that can be used several times subsequently.

The invention refers to a biosensor system for quick and multiplexed detection of biomarkers present in biological fluids. The biosensor system comprises a reusable array of at least two individual electrochemical cells (1a,1b,1c,1d,1e) coupled to a disposable fluidic component. Each cell can be addressed individually. The array includes a set of working electrodes (2a,2b,2c,2d) and at least one shared counter/reference electrode (5) in common for all the electrochemical cells, such that each electrochemical cell includes one working electrode and the shared counter/reference electrode. Preferably, the system includes a disposable paper component (8) having a reactive microfluidic component distributed in fluidic channels (9), isolated by hydrophobic barriers (10). The paper component (8) is operatively aligned with the array of electrochemical cells for the electrochemical detection by means of a polymeric cartridge. The multiplexed biosensor system features a reduced size, and that allows reduction of analysis costs and material waste.

The invention refers to a biosensor system for quick and multiplexed detection of biomarkers present in biological fluids. The biosensor system comprises a reusable array of at least two individual electrochemical cells (1a,1b,1c,1d,1e) coupled to a disposable fluidic component. Each cell can be addressed individually. The array includes a set of working electrodes (2a,2b,2c,2d) and at least one shared counter/reference electrode (5) in common for all the electrochemical cells, such that each electrochemical cell includes one working electrode and the shared counter/reference electrode. Preferably, the system includes a disposable paper component (8) having a reactive microfluidic component distributed in fluidic channels (9), isolated by hydrophobic barriers (10). The paper component (8) is operatively aligned with the array of electrochemical cells for the electrochemical detection by means of a polymeric cartridge. The multiplexed biosensor system features a reduced size, and that allows reduction of analysis costs and material waste.

A method of predictive monitoring of a variable of a medium located in a container of a facility comprises steps of continuously recording data comprising measured values, based on training data determining a classification method capable of identifying data sets that have each been measured during one of the specific operation phases, performing the classification method and based on the data sets identified by the classification method determining a time series of compliancy indicators indicative of a degree of compliancy of at least one property of the characteristic of the measured values to a corresponding reference property of the reference characteristic. Based on the time series at least once determining a time remaining until the degree of compliancy indicated by compliancy indicators will drop below a predetermined minimum degree of compliancy; and providing an output informing about the remaining time.