The invention discloses a device for identifying fluids or measuring their concentration. The device is configured to capture fluid sensing signals and sent to processing capabilities to be annotated, pre-processed and fed to databases of datasets and models which have learning capabilities. The device has a stick or stylus form factor which is makes it fit to be used by health care professionals or by the general public. Advantageously, the stick can be used to capture data from gas and liquid, being possibly phases of the same analyte. The device can be a package containing all processing capabilities being configured to be autonomous. It can operate in conjunction with an intermediary device of a smart phone, a PC or a POCT type. The system comprising autonomous fluid sensory devices, intermediary devices and database servers can operate in a learning mode or in a use mode. Measurements can be filtered, and normalized to statistically eliminate the differences in measurements due to bad operational conditions, differences of device configurations or differences of local parameters (temperature, hygrometry, flow rate, etc. . . . ).

The invention discloses a device for identifying fluids or measuring their concentration. The device is configured to capture fluid sensing signals and sent to processing capabilities to be annotated, pre-processed and fed to databases of datasets and models which have learning capabilities. The device has a stick or stylus form factor which is makes it fit to be used by health care professionals or by the general public. Advantageously, the stick can be used to capture data from gas and liquid, being possibly phases of the same analyte. The device can be a package containing all processing capabilities being configured to be autonomous. It can operate in conjunction with an intermediary device of a smart phone, a PC or a POCT type. The system comprising autonomous fluid sensory devices, intermediary devices and database servers can operate in a learning mode or in a use mode. Measurements can be filtered, and normalized to statistically eliminate the differences in measurements due to bad operational conditions, differences of device configurations or differences of local parameters (temperature, hygrometry, flow rate, etc. . . . ).

A method includes: performing a time-frequency analysis on measurement data to obtain waveform data representing a temporal change in the intensity of each of a plurality of frequency components; dividing the waveform data of each of a plurality of predetermined frequencies into a plurality of segments so that each section where positive values successively occur and each section where negative values successively occur in a time-axis direction are defined as one segment; calculating the area of each of the segments to obtain segment values; creating, for the waveform data of each of the predetermined frequency components, a selected segment group by excluding a segment whose segment value exceeds a predetermined reference value from the segments in the waveform data; and determining a noise level of each of the predetermined frequency components based on the average value of the segment values of the segments included in the selected segment group.

A method for identifying and/or verifying at least one analyte peak in a chromatogram of a sample for said analyte from a liquid chromatography mass spectrometer device, said method comprising: a) determining a chromatogram of the sample by acquiring a plurality of data points for quantifier signal intensities and/or qualifier signal intensities, over time; and, in case the sample comprises an internal standard, optionally acquiring a plurality of data points for internal standard quantifier signal intensities and/or internal standard qualifier signal intensities, over time; b) determining for at least a fraction of the data points acquired in step a), a ratio type; c) comparing the ratios determined in step b) to a reference; and d) identifying and/or verifying at least one analyte peak in a chromatogram based on comparison step c).

A method for identifying and/or verifying at least one analyte peak in a chromatogram of a sample for said analyte from a liquid chromatography mass spectrometer device, said method comprising: a) determining a chromatogram of the sample by acquiring a plurality of data points for quantifier signal intensities and/or qualifier signal intensities, over time; and, in case the sample comprises an internal standard, optionally acquiring a plurality of data points for internal standard quantifier signal intensities and/or internal standard qualifier signal intensities, over time; b) determining for at least a fraction of the data points acquired in step a), a ratio type; c) comparing the ratios determined in step b) to a reference; and d) identifying and/or verifying at least one analyte peak in a chromatogram based on comparison step c).

Disclosed is an organic carbon detector that can be used with a liquid chromatography equipment such as a size exclusion chromatography. The organic carbon detector contains a carbon oxidization subsystem and a stripping and CO.sub.2 detection subsystem arranged and detachably connected with each other in said order. The carbon oxidization subsystem contains a microfluidic agent injection module (1), an inorganic carbon removal module (2), a microfluidic ultraviolet oxidation module (3) and a vacuum pumping system (4), configured to remove inorganic carbons and oxidize organic carbons. The stripping and CO.sub.2 detection subsystem contains a stripping module (7) and a CO.sub.2 detector (12), using a carrier gas to transfer the organic carbon converted gas to the CO.sub.2 detector (12). Also disclosed is a method of using the organic carbon detector in water quality monitoring.

A method for determining a state of a fluidic system can include measuring back pressures in the fluidic system at different times and determining a state of the fluidic system. The determination is based on at least the measured back pressures and on additional status information indicative of at least one status of the fluidic system at at least one of the different times.

A method for determining a state of a fluidic system can include measuring back pressures in the fluidic system at different times and determining a state of the fluidic system. The determination is based on at least the measured back pressures and on additional status information indicative of at least one status of the fluidic system at at least one of the different times.

A gas chromatography guard column assembly is disclosed including a guard column having an inlet and an outlet. The guard column is disposed in a coil having a column coil aspect ratio of less than 15. A gas chromatography system is disclosed including an oven cavity, a heater assembly, an inlet, a guard column, an analytical column, and a detector. The guard column is in fluid communication with the inlet and is disposed in a guard column coil. The analytical column is in fluid communication with the guard column and is disposed in an analytical column coil. The detector is in fluid communication with the analytical column. The analytical column coil has an analytical column coil central axis aligned with a central axis of the heater assembly, and the guard column coil has a guard column coil central axis remote from the central axis of the heater assembly.

A gas chromatography guard column assembly is disclosed including a guard column having an inlet and an outlet. The guard column is disposed in a coil having a column coil aspect ratio of less than 15. A gas chromatography system is disclosed including an oven cavity, a heater assembly, an inlet, a guard column, an analytical column, and a detector. The guard column is in fluid communication with the inlet and is disposed in a guard column coil. The analytical column is in fluid communication with the guard column and is disposed in an analytical column coil. The detector is in fluid communication with the analytical column. The analytical column coil has an analytical column coil central axis aligned with a central axis of the heater assembly, and the guard column coil has a guard column coil central axis remote from the central axis of the heater assembly.