A rotor assembly includes a rotor plate to rotate around a first axis; a bucket rotatably attached to the rotor plate and to rotate around a second axis; and a stop plate to rotate around the first axis relative to the rotor plate between an open position and a closed position, when in the closed position, the stop plate is to engage the bucket to fix an angular position of the bucket relative to a plane of rotation of the rotor assembly.

A well plate includes a including a top portion, a bottom portion and a membrane disposed between the top portion and the bottom portion. The top portion defines a sample well in fluid communication with an opening defined by the membrane and in fluid communication with a reservoir defined by the bottom portion. The well plate is configured to be used in a centrifugation process of a test sample including a sample material and a wash liquid. The test sample configured to be received within the sample well and the reservoir. The membrane configured to filter the wash liquid from the test sample during the centrifugation process such that the wash liquid can pass from the reservoir, through the membrane and can be captured within a collection chamber while the sample material remains within the reservoir.

Blood in a separation chamber is separated into a red blood cell layer, a plasma constituent, and a mononuclear cell-containing layer. A portion of the plasma constituent exits the chamber via a plasma outlet, while a first portion of the red blood cell layer exits via a red blood cell outlet. A second portion of the red blood cell layer exits the chamber via the red blood cell outlet and is collected. At least a portion of the collected red blood cell layer may then be conveyed to the chamber via the red blood cell outlet to convey at least a portion of the mononuclear cell-containing layer out of the chamber via the plasma outlet for collection. A second portion of the plasma constituent may be conveyed out of the chamber via the plasma outlet to more fully collect the mononuclear cell-containing layer without the use of collected plasma.

The sample preparation apparatus includes a measurement unit configured to measure a sample containing particles and detect measurement target particles in the sample, a sample preparation unit capable of adjusting the concentration of measurement target particles in a sample and configured to prepare a measurement sample by mixing a sample and a plurality of types of particle detection reagents, and a control unit configured to generate concentration information of the measurement target particles in the sample based on the measurement data of the measurement unit and adjust the concentration of the measurement target particles in the sample according to the generated concentration information and the type of particle detection reagent.

Systems and methods for guiding the management of blood/plasma screening laboratory workflow are disclosed. A system for analyzing biological samples can include centrifuges, pooling devices, biological sample analyzing devices, and a processor to monitor operation of the centrifuges, the pooling devices, and the biological sample analyzing devices. The processor can track the progress of the biological samples and generate progress indications In response to determining that an external control is present, the system can prevent release of the biological component to the biological sample analyzing device until the external control is also loaded into the analyzer. In response to a component of a biological sample being grouped into more than one pool or not intended to be pooled, the system can generate a warning. The system can provide a chronology of states, display the status of instruments/biological samples, indicate what components need operator attention, and search the status of samples/tests.

A centrifugal microfluidic platform is combined with a stationary liquid pumping system which pumps liquids into microfluidic chips by dripping through a stationary dispensing nozzle without any physical contact or coupling between the nozzles and the microfluidic chips.

Embodiments of the present disclosure relate to a method, system and apparatus for setting a clotting time for a blood sample contained in a container in a laboratory device or test system, which includes setting a clotting start time for the blood sample, setting a clotting wait time to allow for the blood sample to clot, and on positive determination of the completion of the clotting wait time, automatically providing the blood sample for further processing in the laboratory.

A coulter assembly for collecting soil samples from an agricultural field in one embodiment comprises an annular collection blade configured for penetrating soil to capture a sample, an annular cam ring configured for stationary mounting to a frame of an agricultural vehicle and comprising a cam track, a blade hub coupled to the blade for rotatably supporting the annular collection blade from the annular cam ring, and a movable sample collector mounted to the annular collection blade. The moveable sample collector is configured and operable for extracting a soil sample as the annular collection blade is rotated through the soil. The moveable sample collector in one embodiment comprises a piston mechanism including a cylinder and rod movably disposed therein which actuated by the annular cam ring to alternatingly open and close a collection end of the cylinder as the annular collection blade rotates through the soil.

A processing unit for automated preparation of biological samples included in specimen tubes is described herein. The processing unit includes a removable sample preparation component configured to receive specimen tubes, read identifiers associated with the biological samples contained in the specimen tubes, mix reagents included in the specimen tubes, and transfer the specimen tubes to at least one of a centrifuge or a storage compartment. The processing unit further includes a centrifuge loader for automatic loading and unloading of the specimen tubes onto a centrifuge. The automated centrifuge loader includes a magnetic brake that can stop the centrifuge rotor at a precise position to facilitate loading and unloading of a specimen tube. The centrifuge includes a swing bucket designed to pivot around an axis and slide vertically to enable moving the bucket to a position in which the swing bucket can engage with the port where the specimen tube resides.

Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.