According to one embodiment, a particle measuring method is disclosed. The method includes irradiating a detection liquid with light. The detection liquid contains methyl salicylate. The method further includes converting scattered light from the detection liquid into an electric signal by using photoelectric conversion after irradiating the detection liquid with the light. The method further includes performing a particle measurement on the detection liquid by using the electric signal.

Systems and methods which use an optical sensor and an electromagnetic sensor in cooperation for detecting concentrations of one or more materials in solutions are described. In operation according to embodiments of a cooperative optical and electromagnetic sensor material concentration detector, both an optical sensor and electromagnetic sensor are used in cooperation to detect a concentration of a material having a physical feature that is otherwise incompatible with one or the other sensors and/or a material for which measurement is affected by another material present in the sample. Embodiments are, for example, configured to provide a cooperative implementation of optical and electromagnetic sensors operable to detect concentrations of metal ions and acid in a solution, such as for use in real-time material concentration detection.

An analytical assembly within a unified device structure for integration into an analytical system. The analytical assembly is scalable and includes a plurality of analytical devices, each of which includes a reaction cell, an optical sensor, and at least one optical element positioned in optical communication with both the reaction cell and the sensor and which delivers optical signals from the cell to the sensor. Additional elements are optionally integrated into the analytical assembly. Methods for forming and operating the analytical system are also disclosed.

An optical sensing system includes at least one electro-optical sensor having an adjustable field of view and at least one reflective member including a diffuse reflector surface positioned within the field of view of the at least one electro-optical sensor. The system also includes at least one controller configured to generate calibration parameters for the at least one electro-optical sensor based on data for at least one exposure detected by the electro-optical sensor when the diffuse reflector surface is within the field of view of the at least one electro-optical sensor. Methods for calculating the calibration parameters and for directly measuring reflectivity of objects in a scene with at least one electro-optical sensor are also disclosed herein.

A polarization property image measurement device includes: a first radiation unit that radiates light beams in different polarization conditions onto a target object after subjecting the light beams to intensity modulation at frequencies different from one another; a light receiving unit including first photoelectric conversion units that photoelectrically convert the light beams having been radiated from the first radiation unit and scattered at the target object in correspondence to each of the different polarization conditions, and second photoelectric conversion units that photoelectrically convert visible light from the target object; and a processor that detects signals individually output from the first photoelectric conversion units at the different frequencies and differentiates each signal from other signals so as to determine an origin of the signal as one of the light beams; and creates an image of the target object based upon signals individually output from the second photoelectric conversion units.

An analytical assembly within a unified device structure for integration into an analytical system. The analytical assembly is scalable and includes a plurality of analytical devices, each of which includes a reaction cell, an optical sensor, and at least one optical element positioned in optical communication with both the reaction cell and the sensor and which delivers optical signals from the cell to the sensor. Additional elements are optionally integrated into the analytical assembly. Methods for forming and operating the analytical system are also disclosed.

A polarization property image measurement device includes: a first radiation unit that radiates light beams in different polarization conditions onto a target object after subjecting the light beams to intensity modulation at frequencies different from one another; a light receiving unit including first photoelectric conversion units that photoelectrically convert the light beams having been radiated from the first radiation unit and scattered at the target object in correspondence to each of the different polarization conditions, and second photoelectric conversion units that photoelectrically convert visible light from the target object; and a processor that detects signals individually output from the first photoelectric conversion units at the different frequencies and differentiates each signal from other signals so as to determine an origin of the signal as one of the light beams; and creates an image of the target object based upon signals individually output from the second photoelectric conversion units.

A device and an according method for multispectral optoacoustic imaging of an object is provided comprising: an irradiation unit configured to irradiate the object with electromagnetic radiation at two or more different irradiation wavelengths the electromagnetic radiation having a time-varying intensity; a detection unit configured to detect acoustic waves generated in the object upon irradiating the object with the electromagnetic radiation at the different irradiation wavelengths; and a processing unit configured to reconstruct images of the object based on the detected acoustic waves generated in the object at each of the irradiation wavelengths and to determine a spatial distribution of at least one first concentration value, which relates to a concentration of at least one electromagnetic radiation absorber in the object.

A photoacoustic measurement device having a puncture needle, where the puncture needle 14 is a hollow needle that has an opening formed at a tip thereof. The puncture needle 14 includes a puncture needle body 31 and a light guide 32. The light guide 32 extends in a longitudinal direction of the puncture needle body. The light guide 32 emits light at least in part to the puncture needle body 31 while guiding light emitted from a light source toward the tip of the puncture needle body.

Systems and methods are provided for excitation spectral microscopy using frame-synchronized acousto-optic scanning of fluorescent excitation wavelengths. Linear unmixing of the images of targets of components that are individually labeled with different fluorophores can be simultaneously imaged with high temporal resolution and low crosstalk and the local abundance of each fluorophore at each pixel can be quantified. Fluorophore decomposed micrographs of the sample can be obtained by rendering the abundance in each pixel as an image.