The present invention refers to a detector and a method for obtaining Kikuchi images by using electron backscatter diffraction (EBSD) or transmission Kikuchi diffraction (TKD) technique. In particular, the present invention refers to a detector comprising a detector body, a detector head with a scintillation screen and a photodetector with a active surface for detecting Kikuchi patterns, and means configured to move the detector head with respect to the detector body. The method comprises obtaining a first and a second Kikuchi pattern, and moving the detector head after obtaining the first Kikuchi pattern and prior obtaining the second Kikuchi pattern.

An X-ray computed tomography (CT) scanner includes a plurality of X-Ray sources and detectors mounted about an opening where scanning takes place. The X-Ray sources and detectors are arranged to oscillate back and forth in opposing first and second rotational directions about the opening, or in the same rotational direction about the opening, in order to generate a cross-sectional image of an object located within the opening.

The present disclosure relates to a procedure for generating fluoroscopic images for the reconstruction of a volume in a flat object using an X-ray system, which has three imaging components, namely a tube, a detector and a manipulator, located between them, on which the object is fixed. The object extends multiple times further in two dimensions than in its third dimension. The tube has a focus, which, in a central position of the tube, forms the coordinate origin of a Cartesian coordinate system, and which emits an X-ray. The vector from the tube through the volume forms the x axis of the coordinate system and the z axis is perpendicular to a vector formed through the thickness. The manipulator is rotated about a rotational axis, which is perpendicular to the x axis, runs parallel to the z axis and is displaceable parallel to the x axis.

An apparatus for imaging and analyzing a tissue sample includes a rotating table with integrated weighing apparatus for supporting and rotating a platform supporting a tissue sample. A laser line generator projects a laser line onto the platform and the tissue sample. A profiling camera captures images of the laser line upon the tissue sample as the platform and tissue sample are rotated. An image analyzer/processor determines a plurality of laser lines profiles from the captured images of the laser line. The image analyzer/processor determines a tissue profile of the tissue sample from the plurality of laser line profiles.

A method for automatically altering an imaging area in microscopic imaging of a biological sample. In the method, a sample outline is differentiated from surrounding tissues by means of endogenous or exogenous markers; an initial sample imaging area is set; optical microscopic imaging is performed on a sample surface layer, wherein the imaging area is larger than an area to be imaged of the sample; an actual sample area is calculated by an outline identification algorithm using an imaging result of the sample surface layer and is set as an imaging area of next layer; optical microscopic imaging is performed on a sample to be imaged of the next layer according to the set imaging area, wherein the imaging area covers the area to be imaged of the sample and no redundant imaging is performed; and the above steps are repeated until a data acquisition task is completed.

System and method for imaging an integrated circuit (IC). The imaging system comprises an x-ray source including a plurality of spatially and temporally addressable electron sources, an x-ray detector arranged such that incident x-rays are oriented normal to an incident surface of the x-ray detector and a three-axis stage arranged between the x-ray source and the x-ray detector, the three-axis stage configured to have mounted thereon an integrated circuit through which x-rays generated by the x-ray source pass during operation of the imaging system. The imaging system further comprises at least one controller configured to move the three-axis stage during operation of the imaging system and selectively activate a subset of the electron sources during movement of the three-axis stage to acquire a set of intensity data by the x-ray detector as the three-axis stage moves along a three-dimensional trajectory.

A calculating unit for calculating a recording trajectory of a CT system has a receive interface, an optimizer and a control unit. The receive interface serves for receiving measurement and simulation data relative to the object to be recorded. The optimizer is configured to determine the recording trajectory based on known degrees of freedom of the CT system, based on the measurement and simulation data and based on a test task from a group having a plurality of test tasks. The control unit is configured to output data in correspondence with the recording trajectory for controlling the CT system.

Various embodiments are described herein for a system and method of integrated X-ray imaging and microscopic imaging of an imaging area having a sample on a sample stage. An X-ray apparatus may be disposed within the imaging area and be configured to acquire X-ray image data of at least a portion of the sample. A microscopic imaging apparatus may be disposed within the imaging area and be configured to acquire microscopic image data of the at least a portion of the sample. In some embodiments, a processing unit may then control the X-ray apparatus to acquire X-ray image data of the at least the portion of the sample, and generate one or more corresponding X-ray images; determine a region of interest (ROI) of the sample based on the one or more X-ray images; and control the microscopic imaging apparatus to obtain at least one microscopic image based on the ROI.

An apparatus and method for three-dimensional inspection of an object by X-rays. The apparatus includes an X-ray generator and a digital imaging device spaced from each other by a distance which defines a magnification by 1 on the imaging device. The apparatus also includes a means for moving the X-ray generator and identically the imaging device by unitary movements in two orthogonal directions. Each unitary movement corresponds to an integer number fraction of the side of the imaging device, and obtains, by successive shots after each unitary movement, a matrix set of sub-images overlapping in the plane of extension of the imaging device. Each sub-image has a center with coordinates in a plane of magnification equal to N. An image processing means performs magnification of each sub-image and determines a stretch factor enabling the coincidence of the sub-images representing all or part of a predefined element of interest.

A method for automatically altering an imaging area in microscopic imaging of a biological sample. In the method, a sample outline is differentiated from surrounding tissues by means of endogenous or exogenous markers; an initial sample imaging area is set; optical microscopic imaging is performed on a sample surface layer, wherein the imaging area is larger than an area to be imaged of the sample; an actual sample area is calculated by an outline identification algorithm using an imaging result of the sample surface layer and is set as an imaging area of next layer; optical microscopic imaging is performed on a sample to be imaged of the next layer according to the set imaging area, wherein the imaging area covers the area to be imaged of the sample and no redundant imaging is performed; and the above steps are repeated until a data acquisition task is completed.