Cells are grown in 3D culture and topological features obtained by photomicrography are correlated to cell viability and cell cell interactions.

A method and system for detecting a target molecule. The method includes allowing a fluid containing the target molecule to pass by a complementary moiety attached to a paramagnetic ion so as to cause the complementary moiety and the paramagnetic ion to change a position. A magnetic effect change caused by the change in position of the paramagnetic ion is detected. The target molecule is identified based on the identity of the complementary moiety and the detected magnetic effect change.

What provided is a biosensor including: a substrate having a surface with first and second regions adjacent to each other; a magnetoresistance effect element that is disposed at least on the first region and is configured for a detected resistance value to be changed based on an input magnetic field; a protective film that is disposed on both the first region and the second region, covers a surface of the magnetoresistance effect element, is disposed on the top part of the first region and contains an affinity substance capable of recognizing the biomolecule on the outer surface of the first region exclusively; and an adsorption prevention film that is disposed on at least the top part of the second region and is substantially free of the affinity substance, wherein the protective film and the adsorption prevention film are made of different materials.

To provide a chemical sensor that enables high detection accuracy. A chemical sensor includes a substrate, two or more magnetoresistance-effect elements disposed side by side in a substrate in-plane direction over the substrate, a first film disposed over a region between the magnetoresistance-effect elements adjacent to each other, and a second film disposed over the magnetoresistance-effect elements, wherein the second film has higher solubility in a specific liquid than the first film.

A chemical sensor that enables high detection accuracy. A chemical sensor includes a substrate, a magnetoresistance-effect element disposed over the substrate, a first film disposed over the magnetoresistance-effect element, and a second film disposed in a region in the vicinity of the magnetoresistance-effect element or over a region in the vicinity of the magnetoresistance-effect element, wherein the second film has higher solubility in a specific liquid than the first film.

Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the invention.

Cells are grown in 3D culture and topological features obtained by photomicrography are correlated to cell viability and cell interactions.

Aspects of the subject technology relate to systems, methods, and computer-readable media for corrosion analysis using magnetic flux leakage measurements. The present technology can magnetic flux leakage data obtained by a magnetic flux leakage tool placed in a pipe within a wellbore and convert the magnetic flux leakage data into image data. Further, the present technology can provide the image data to a machine learning model. The machine learning model is configured to identify one or more physical parameters associated with corrosion present on the pipe.

Aspects of the subject technology relate to systems, methods, and computer-readable media for corrosion analysis using magnetic flux leakage measurements. The present technology can magnetic flux leakage data obtained by a magnetic flux leakage tool placed in a pipe within a wellbore and convert the magnetic flux leakage data into image data. Further, the present technology can provide the image data to a machine learning model. The machine learning model is configured to identify one or more physical parameters associated with corrosion present on the pipe.

A system for gene detection includes a sensor module including a plurality of magnetic sensors in an arrangement of a matrix and a signal processing chip including a front-end circuit and a signal processing circuit. The sensor module is formed on the signal processing chip through sputtering. The signal processing chip is configured to transform variation of the reluctivity of the magnetic sensors into a first electrical signal, process the first electrical signal and output a second electrical signal representing a detection result of a DNA molecule to be detected. The front-end circuit includes a row address selector, a column address selector, a pre-amplifier and a biasing circuit. The magnetic sensors are chemically pretreated and combined with a biological probe. The combined magnetic sensors and biological probe are in sufficient contact with combined magnetic particles and DNA molecules to be detected.