An optical adapter for connecting between a beam splitter of a surgical microscope or an ophthalmic slit lamp microscope and a digital camera equipment including mobile phones, tablet computers, cameras, video cameras with image capturing function is provided. The optical adapter includes a lens group located on an optical path and an optical image rotating lens group for adjusting a direction of an optical image on a photosensitive unit of the digital camera equipment. The optical image rotating lens group is configured to be either independently rotatable around optical axis or be set fixedly. Embodiments of the present invention provide a system and method for real-time adjustment of the direction of an optical image on the photosensitive unit of a digital camera equipment, where regardless of the position of the digital camera a satisfactory direction of the optical image can be obtained with a simple user friendly and convenient structure.

Methods and systems for digitally reconstructing a patient tissue sample are described herein. In one embodiment, the method may include projecting a first structured light pattern onto the patient tissue sample, receiving a first reflection of the first structured light pattern from the patient tissue sample, and reconstructing the patient tissue sample based on the first reflection and the projected first structured light pattern. In another embodiment, the system may include a projector adapted or configured to project the first structured light onto the patient tissue sample, a charge-coupled device (CCD) adapted or configured to receive the first reflection from the patient tissue sample, and a reconstruction device adapted or configured to reconstruct the patient tissue sample based on the first reflection and the projected first structured light pattern.

A microscope includes a digital imaging device. The digital imaging device comprises a processor which is configured to: obtain a number of digital grayscale images of an object at a number of different spectral sensitivities, each of the digital grayscale images including grayscale information based on a different one of the different spectral sensitivities, obtain a number of weighting factors for each of the digital grayscale images, the weighting factors being allocated to a number of color channels defining a predetermined color space, and synthesize a digital color image of the object from the digital grayscale images in the color space by distributing the grayscale information of each grayscale image over the color channels in accordance with the weighting factors.

An optical imaging system for imaging a target during a medical procedure, the optical imaging system involving a first camera for capturing a first image of the target, a second wide-field camera for capturing a second image of the target, at least one optional path folding mirror disposed in an optical path between the target and a lens of the second camera, and a processor for receiving the first image and the second image, the processor configured to apply an image transform to one of the first image and the second wide-field image and combine the transformed image with the other one of the images to produce a stereoscopic image of the target.

A modular microscope can quickly be modified for specific scanning applications. The microscope includes a microscope main body which has slots into which long pass filter modules, dichroic mirror modules, notch filter modules, and LED modules can be selectively placed, removed, and changed out. In some applications, the interchangeable components permit quickly changing between Photoluminescence (PL) and Raman spectroscopy (microscope) systems.

Diffraction-based imaging systems are described. Aspects of the technology relate to imaging systems having one or more sensors inclined at angles with respect to a sample plane. In some cases, multiple sensors may be used that are, or are not, inclined at angles. The imaging systems may have no optical lenses and are capable of reconstructing microscopic images of large sample areas from diffraction patterns recorded by the one or more sensors. Some embodiments may reduce mechanical complexity of a diffraction-based imaging system. A diffractive imaging system comprises a light source, a sample support configured to hold a sample along a first plane, and a first sensor comprising a plurality of pixels disposed in a second plane that is tilted at an inclined angle relative to the first plane. The first sensor is arranged to record diffraction images of the light source from the sample.

A detection optical system includes an objective lens, a first relay lens, a second relay lens, and an imaging lens, which are arranged in order from a side of a specimen along an optical path of light from the specimen illuminated by a light source. A primary imaging plane is provided on the optical path between the first relay lens and the second relay lens. An aspherical correction plate that corrects spherical aberration is arranged at a position located between the second relay lens and the imaging lens and substantially conjugate with a pupil position of the objective lens.

Provided is a solid-state illumination system for use in a microscopy system utilizing a light sensor of a mobile phone camera module. The system includes a bright-field illumination source with an array of light-emitting diodes (LEDs). The array of LEDs is configured to produce transmission light within a range of view of the light sensor of the mobile phone camera module. The system also includes a dark-field illumination source including a ring of LEDs. The ring of LEDs is configured to produce light outside of the range of collection of the camera module lens. The system also includes a diffuser configured to diffuse the transmission light and a diffusive black material coupled to the diffuser. The diffusive black material is configured to pass through at least some of the transmission light while blocking reflections of the scattering light.

Provided are a fiber bundle image processing method (200) and an apparatus. The method (200) includes: determining pixel information corresponding to a center position of a fiber in a sample image; correcting the determined pixel information; and reconstructing the sample image based on the corrected pixel information to obtain a reconstructed image. The method (200) and apparatus can not only obtain a more ideal fiber-bundle processed image, but also have a smaller calculation amount, and the entire calculation process takes less time.

The present disclosure relates to a medical microscope field. A stereo microscope connected to an optical coherence tomography (OCT) unit for forming a tomographic image of a target object includes an objective lens unit including a plurality of lenses each having an aperture of a predetermined size, a pair of first magnification lens units each including a plurality of lenses having a pair of magnification lens apertures positioned within the aperture of the objective lens unit, a second magnification lens unit including a plurality of lenses having an OCT aperture disposed separately from the pair of magnification lens aperture within the aperture of the objective lens unit, and a light delivery unit configured to receive light from the OCT unit and deliver the light to the second magnification lens unit and configured to deliver light received from the second magnification lens unit to the OCT unit.