A fluorescence detection system is provided and adapted to provide a selectable excitation beam to an optical transmission path for irradiation of a device under test, including a driving module, a lighting module, a first optical module and a second optical module. The driving module includes a first shaft and a second shaft parallel thereto. The lighting module is fixed to the first shaft. The first optical module and the second optical module are fixed to the second shaft. A driving operation enables the driving module to rotate the lighting module, the first optical module and the second optical module simultaneously, determining quickly a combination of one light source, one filter and one spectroscopic module on the optical transmission path, with the combination corresponding in position to the device under test, so as to reduce the volume and cost the fluorescence detection system.

A spectrometer includes a support having a bottom wall part and a side wall part arranged on one side of the bottom wall part, a light detection element supported by the support to face a surface of the bottom wall part on the one side through a spectroscopic space, a resin molded layer provided at least on the surface of the bottom wall part on the one side, and a reflecting layer provided on the resin molded layer and included in an optical function part on the bottom wall part. The resin molded layer has a first part having a shape corresponding to the optical function part and a second part which surrounds the first part and is thinner than the first part.

An optical assembly for an analyzer instrument for analysis of elemental composition of a sample using optical emission spectroscopy includes: an exciter generating an excitation focused at a target position to produce optical emission from the sample; and an optical arrangement including a light collection arrangement transferring the optical emission from the target position to a detector assembly's detector interface. The light collection arrangement includes: an off-axis parabolic light collecting mirror including an aperture, a lens arrangement including converging and diverging axicon lens portions, the lens arrangement positioned so its optical axis is parallel to that of the light collecting mirror and intersects a surface of the light collecting mirror at the aperture, and an off-axis parabolic focusing mirror having its focal point at the detector interface, the optical axis of the lens arrangement being parallel to that of the focusing mirror and intersects the focusing mirror's surface.

A multi-pixel spectroscopy sensor for spectral analysis of a sample under test including an array of pixel elements generating a dataset including a plurality of data values corresponding to the pixel elements upon illumination of the sample by a light source. Each of the pixel elements including a stack of layers including first and second reflective structures, a phase tuning element, a detector element, and contact elements. The sensor further includes a read-out circuit connected to each of the contact elements for simultaneous read-out of a plurality of photocurrents for generating and outputting the dataset for the spectral analysis of the sample under test. The phase tuning element of each of the pixel elements is configured for a different wavelength response of the light and each photodetector of the pixel elements is comprised of a semiconductor material.

A system, an apparatus, and a method are provided for a modular flow cytometer with a compact size. In one embodiment, the modular flow cytometry system includes the following: a laser system for emitting laser beams; a flow cell assembly positioned to receive the laser beams at an interrogation region of a fluidics stream where fluoresced cells scatter the laser beams into fluorescent light; a fiber assembly positioned to collect the fluorescent light; and a compact light detection module including a first image array having a transparent block, a plurality of micro-mirrors in a row coupled to a first side of the transparent block, and a plurality of filters in a row coupled to a second side of the transparent block opposite the first side.

Methods and devices to implement mid-wave and long-wave infrared point spectrometers are disclosed. The described methods and devices involve bi-faceted gratings, high-operating-temperature barrier infrared and thermal detectors. The disclosed concept can be used to design flight spectrometers that cover broad solar reflectance plus thermal emission spectral ranges with a compact and low-cost instrument suitable for small spacecraft reconnaissance of asteroids, the Moon, and planetary satellites as well as mass-constrained landed missions.

A compact spectrometer includes an excitation light source configured to generate excitation light and arranged to illuminate a spot on a sample. A dispersive element includes at least one movable component and spatially separates output light emanating from the sample in response to the excitation light into a plurality of different wavelength bands. A moveable component of the dispersive element causes the plurality of different wavelength bands of the output light to be scanned across a detector. The detector includes at least one light sensor that senses the wavelength bands of the output light and generates an output electrical signal in response to the sensed output light.

Provided herein are accessories for measuring a small sample using an optical spectrometer. A small sample accessory may include a sample holder to hold a small sample in optical communication with an optical spectrometer and a shell configured to reflect light from an illumination source away from the optical spectrometer.

A controller corrects a spectrum S (λ) detected at a wavelength λ of signal light to S′ (λ) in accordance with expressions below: I(λ)=(I2−I1)×(λ−λ1)/(λ2−λ1)−I1, and S′(λ)=S(λ)−I(λ), where I1 is the intensity of infrared light detected at a wavelength λ1 of reference light and I2 is the intensity of infrared light detected at a wavelength λ2 of correction light.

High-throughput hyperspectral imaging systems are provided. According to an aspect of the invention, a system includes an excitation light source; an objective that is configured to image excitation light onto the sample, such that the excitation light causes the sample to emit fluorescence light; a channel separator that is configured to separate the fluorescence light into a plurality of spatially dispersed spectral channels; and a sensor. The excitation light source includes a light source and a plurality of lenslet arrays. Each of the lenslet arrays is configured to receive light from the light source and to generate a pattern of light, and the patterns of light generated by the lenslet arrays are combined to form the excitation light. The objective is configured to simultaneously image each of the patterns of light to form a plurality of parallel lines or an array of circular spots at different depths of the sample.