G01N21/91

Nucleated red blood cell analysis system and method

Systems and methods for analyzing blood samples, and more specifically for performing a nucleated red blood cell (nRBC) analysis. The systems and methods screen a blood sample by means of fluorescence staining and a fluorescence triggering strategy, to identify nuclei-containing particles within the blood sample. As such, interference from unlysed red blood cells (RBCs) and fragments of lysed RBCs is substantially eliminated. The systems and methods also enable development of relatively milder reagent(s), suitable for assays of samples containing fragile white blood cells (WBCs). In one embodiment, the systems and methods include: (a) staining a blood sample with an exclusive cell membrane permeable fluorescent dye; (b) using a fluorescence trigger to screen the blood sample for nuclei-containing particles; and (c) using measurements of light scatter and fluorescence emission to distinguish nRBCs from WBCs.

Basophil analysis system and method

Provided herein are systems and methods for analyzing blood samples, and more specifically for performing a basophil analysis. In one embodiment, the systems and methods include: (a) staining a blood sample with an exclusive cell membrane permeable fluorescent dye; and then (b) using measurements of light scatter and fluorescence emission to distinguish basophils from other WBC sub-populations. In one embodiment, the systems and methods include performing a basophil cluster analysis of the blood sample, based on the combination of light scatter and fluorescence measurements.

FLUORESCENT LIQUID PENETRANTS AND METHODS OF NONDESTRUCTIVE TESTING
20170261313 · 2017-09-14 · ·

A fluorescent liquid penetrant is provided which includes a liquid medium having a plurality of fluorophores disposed therein. Upon excitation with a suitable light source, the penetrant exhibits a quantum yield greater than 40% (or in some embodiments, greater than 90%). In some embodiments, the fluorophore is a low-toxicity quantum dot. In some embodiments, the fluorophore has significantly reduced self-absorption, which allows for surface discontinuity depth measurement. Also disclosed are apparatuses for using these fluorescent liquid penetrants for non-destructive testing purposes. In some embodiments, these tests include measuring the depth of a discontinuity by analyzing photoluminescence intensity and/or photoluminescence peak position shift.

LIGHT AND METHOD FOR OPERATING A LIGHT
20170257923 · 2017-09-07 ·

A light, in particular for testing workpiece surfaces using a fluorescent marking device, which light has at least two lighting elements that emit electromagnetic radiation with different wavelength ranges. The intensity with which the lighting element irradiates can be adjusted separately for at least one of the lighting elements. Expediently, the light is configured to increase or reduce the intensity of at least one of the lighting elements and at the same time to keep the intensity of at least one other of the lighting elements constant, or to reduce it or increase it in the opposite way to the first-mentioned lighting element. The light is configured to adjust the intensity at such a speed that the human eye can adapt to a change in the intensity during the adjustment without adverse effects on the person's sight.

METHODS AND SYSTEMS FOR NON-DESTRUCTIVE TESTING (NDT) WITH TRAINED ARTIFICIAL INTELLIGENCE BASED PROCESSING
20210407070 · 2021-12-30 ·

Systems and methods are provided for non-destructive testing (NDT) with trained artificial intelligence based processing.

SYSTEM AND METHOD FOR IMPROVED CYCLE TIME MILLING AND INSPECTION

This invention relates to both process and tooling for machining exemplary Hamilton Sundstrand 7111 and 7121 aircraft propeller blade taper bores, or equivalent to comply with government and or industry standards or specifications for such refurbishment. The tooling and process invented are an Improvement over previous and current taper bore machining methods in improved repeatability and cost effectiveness, as this machining method can quickly and repeatedly machine propeller blades to meet fit, form, and function requirements. The process makes use of a specially constructed horizontal mill, specially constructed blade-holding fixture, specially constructed probing system, specially constructed reamers, and specially constructed air gauges. A blade holding fixture assembly including a base plate, a blade holding fixture and a blade alignment fixture hold an aircraft propeller blade in a horizontal milling machine for refurbishment of the taper bores. Refurbishment includes reaming shot peened surfaces, testing the reamed surfaces with an air gauge and a fluorescent penetrant emersion fixture.

SYSTEM AND METHOD FOR IMPROVED CYCLE TIME MILLING AND INSPECTION

This invention relates to both process and tooling for machining exemplary Hamilton Sundstrand 7111 and 7121 aircraft propeller blade taper bores, or equivalent to comply with government and or industry standards or specifications for such refurbishment. The tooling and process invented are an Improvement over previous and current taper bore machining methods in improved repeatability and cost effectiveness, as this machining method can quickly and repeatedly machine propeller blades to meet fit, form, and function requirements. The process makes use of a specially constructed horizontal mill, specially constructed blade-holding fixture, specially constructed probing system, specially constructed reamers, and specially constructed air gauges. A blade holding fixture assembly including a base plate, a blade holding fixture and a blade alignment fixture hold an aircraft propeller blade in a horizontal milling machine for refurbishment of the taper bores. Refurbishment includes reaming shot peened surfaces, testing the reamed surfaces with an air gauge and a fluorescent penetrant emersion fixture.

METHOD FOR CHECKING COMPLIANCE OF A MECHANICAL PART OF A VEHICLE
20220178840 · 2022-06-09 · ·

A method for checking compliance of a mechanical part of a vehicle, including an image capture step for producing a study image of the mechanical part, and a step of analysing the study image by an analysis unit, said analysis step including a results phase transmitting a results signal indicating whether the mechanical part is compliant or, on the contrary, non-compliant.

FLUORESCENCE FILTER AND IMAGE SENSOR MODULE INCLUDING SAME
20220170860 · 2022-06-02 · ·

The present disclosure relates to a fluorescence filter for measuring fluorescence generated by a measurement object and an image sensor module including the same, and includes an absorption filter transmitting light within a specific wavelength band generated by the measurement object including a fluorescent dye and absorbs light in the remaining wavelength bands, and a reflection filter that is disposed adjacent to the absorption filter, transmits light within a specific wavelength band generated by the measurement object, and reflects light in the remaining wavelength bands, wherein the absorption filter has a plurality of wells having a predetermined depth in which the measurement object is accommodated, and wherein the plurality of wells are disposed at regular intervals on an incident surface of the absorption filter to which external light is incident.

FLUORESCENCE FILTER AND IMAGE SENSOR MODULE INCLUDING SAME
20220170860 · 2022-06-02 · ·

The present disclosure relates to a fluorescence filter for measuring fluorescence generated by a measurement object and an image sensor module including the same, and includes an absorption filter transmitting light within a specific wavelength band generated by the measurement object including a fluorescent dye and absorbs light in the remaining wavelength bands, and a reflection filter that is disposed adjacent to the absorption filter, transmits light within a specific wavelength band generated by the measurement object, and reflects light in the remaining wavelength bands, wherein the absorption filter has a plurality of wells having a predetermined depth in which the measurement object is accommodated, and wherein the plurality of wells are disposed at regular intervals on an incident surface of the absorption filter to which external light is incident.