A method is disclosed that permits calculation of reagent concentrations (in SI units) over time and space within a tissue sample as the sample is immersed in the reagent and the reagent diffuses into the tissue sample. The disclosed method has yielded the surprising result that once a formaldehyde concentration at all points within a tissue sample exceeds about 90 mM during a cold step of a cold+hot fixation protocol, the hot step of the fixation protocol can be commenced to provide reliable detection of molecular targets and preservation of tissue morphology in downstream analyses.

Systems and methods for prediction of state of charge (SOH), state of health (SOC) and other characteristics of batteries using acoustic signals, includes determining acoustic data at two or more states of charge and determining a reduced acoustic data set representative of the acoustic data at the two or more states of charge. The reduced acoustic data set includes time of flight (TOF) shift, total signal amplitude, or other data points related to the states of charge. Machine learning models use at least the reduced acoustic dataset in conjunction with non-acoustic data such as voltage and temperature for predicting the characteristics of any other independent battery.

The apparatus for inspecting the electrostatic chuck for substrate processing includes the electrostatic chuck including a ceramic layer and an electrode layer coupled to an inside of the ceramic layer, an ultrasonic sensor unit disposed on the electrostatic chuck, allowing an ultrasonic wave to be incident into the electrostatic chuck, and converting a reflected signal reflected through the electrostatic chuck into an ultrasonic voltage signal, and an ultrasonic inspection unit to divide the ceramic layer and the electrode layer, based on a size value of the ultrasonic voltage signal.

A computer system is provided for processing ultrasonic data of an ultrasonic probe applied to an area of an aircraft component that includes carbon fiber reinforced polymer. C-scan data is obtained and a preliminary mesh is defined over the C-scan data by taking into account the underlying structural or mechanical characteristics of the analyzed component. The mesh is further refined and data gathered for each mesh cell. A heat map is generated based on the mesh.

A method for inspecting a fastened structure, the fastened structure having at least one structural member defining a bore therein and a mechanical fastener received in the bore, includes applying acoustic energy to the fastened structure, the acoustic energy being applied over a plurality of frequencies, measuring a response of the fastened structure across at least two frequencies of the plurality of frequencies, and comparing the response of the fastened structure at the at least two frequencies of the plurality of frequencies to predefined values for the at least two frequencies of the plurality of frequencies to determine whether an out-of-tolerance condition is present.

An apparatus and method for detecting an initial lubrication of a moving component including an ultrasonic sensor for detecting an ultrasonic output signal from the moving component and a processor for operating on the output signal. The processor determines if there has been an initiation of a lubrication operation. After identifying the initiation of the lubrication operation, the processor monitors the ultrasonic output signal received from the ultrasonic sensor to detect a momentary increase in the amplitude of the ultrasonic output signal above a level that indicates a need for lubrication, and which is indicative of an initial interaction between a lubricant and the moving component. Upon detecting the momentary increase in the amplitude, the processor tracks a progress of the lubrication operation by detecting for a sustained decrease in the amplitude of the ultrasonic output signal received from the ultrasonic sensor.

A sensing system contains a vibration device attached to a stem of an agricultural crop for applying vibration to the agricultural crop, at least one sensor attached to the stem of the agricultural crop for sensing vibration of the agricultural crop caused by the vibration applied to the agricultural product from the vibration device to transmit vibration information relate to the vibration of the agricultural crop and a computing device for identifying one local maximum value among a plurality of local maximum values in a frequency spectrum obtained from the vibration information received from the at least one sensor as a resonance frequency of the vibration of the agricultural crop to determine a growth degree of a fruit of the agricultural crop based on the identified resonance frequency.

Methods, systems, and computer storage media for providing an indication of an integrity of an object based on a non-invasive assessment of the integrity of the object using acoustic signature management engine in object integrity sensing system. In operation, an aggregate object-intermediate-medium sound of an object in an intermediate medium is detected (e.g., via sensors). An acoustic signature of the aggregate object-intermediate-medium sound is generated as a processed acoustic channel associated with statistical measurements. A reference acoustic signature of the object and intermediate medium is accessed. The reference acoustic signature is associated with an acoustic signature computation model, that generates reference acoustic signatures based on a mean and standard deviation measurements of input signals transmitted through the object and intermediate medium. A determination whether the object has impaired integrity is determined based on a quantified difference between the acoustic signature of the aggregate object-intermediate-medium sound and the reference acoustic signature.

A system for estimating both thickness and wear state of refractory material (1) of a metallurgical furnace (12), including at least on processor including a database of simulated frequency domain data named simulated spectra representing simulated shock waves reflected in simulated refractory materials of known state and thickness, each simulated spectrum being correlated with both known state and thickness data of the considered simulated refractory material, wherein the at least one processor is configured to record a reflected shock wave as a time domain signal, and to convert it into frequency domain data named experimental spectrum, and are further configured to compare the experimental spectrum with at least a plurality of simulated spectra from the database, to determine the best fitting simulated spectrum with the experimental spectrum and to estimate thickness and state of the refractory material (1) of the furnace (12) using known state and thickness data correlated with the best fitting simulated spectrum.

A system for detecting a sub-surface defect comprising a transducer fluidly coupled to a part located in a tank containing a liquid configured to transmit ultrasonic energy, the transducer configured to scan the part to create scan data of the scanned part; a pulser/receiver coupled to the transducer configured to receive and transmit the scan data; a processor coupled to the pulser/receiver, the processor configured to communicate with the pulser/receiver and collect the scan data; and the processor configured to detect the sub-surface defect and the processor configured to have a sub-surface defect confidence assessment and a prioritization for further human evaluation.