One end of carrier gas channel, purge gas channel and split gas channel is connected to sample gasification chamber. The other end of carrier gas channel, purge gas channel, and split gas channel is connected to a flow rate control mechanism in the form of carrier gas flow rate control block, purge gas flow rate control block and split gas flow rate control block respectively. Carrier gas flow rate control block, purge gas flow rate control block and split gas flow rate control block constitute a flow rate control unit. This reduces the possibility of leakage of gas to the outside and admixture of impurities from the outside in the flow rate control mechanism.

One end of carrier gas channel, purge gas channel and split gas channel is connected to sample gasification chamber. The other end of carrier gas channel, purge gas channel, and split gas channel is connected to a flow rate control mechanism in the form of carrier gas flow rate control block, purge gas flow rate control block and split gas flow rate control block respectively. Carrier gas flow rate control block, purge gas flow rate control block and split gas flow rate control block constitute a flow rate control unit. This reduces the possibility of leakage of gas to the outside and admixture of impurities from the outside in the flow rate control mechanism.

Provided are methods for determining the apolipoprotein E (ApoE) phenotype in a sample by mass spectrometry; wherein the ApoE allele(s) present in the sample is determined from the identity of the ions detected by mass spectrometry. In another aspect, provided herein are methods for diagnosis or prognosis of Alzheimer's disease or dementia.

Provided are methods for determining the apolipoprotein E (ApoE) phenotype in a sample by mass spectrometry; wherein the ApoE allele(s) present in the sample is determined from the identity of the ions detected by mass spectrometry. In another aspect, provided herein are methods for diagnosis or prognosis of Alzheimer's disease or dementia.

Provided is a method for detecting impurities in ammonium hydroxide. The method for detecting impurities in ammonium hydroxide includes preparing a potassium permanganate solution, preparing ammonium hydroxide, and adding the potassium permanganate solution several times to the ammonium hydroxide so as to detect impurities in the ammonium hydroxide. Potassium permanganate contained in the potassium permanganate solution is added for each time in the range of 0.0001 mol to 0.01 mol per 1 g of ammonia contained in the ammonium hydroxide.

The culture medium processing system includes a controller (100) configured to control operation of a sample dispensing part (20), a reagent dispensing part (26) and a transport arm (24) to deproteinize a sample, wherein the controller (100) is configured to dispense a methanol solution into an empty filtration container (50) to perform a conditioning of a filtration filter (52) disposed in the filtration container (50), then dispense a sample into the filtration container (50), add an acetonitrile solution as a deproteinization agent to the sample in the filtration container (50), and then perform a filtration process in the filtration part (30).

The culture medium processing system includes a controller (100) configured to control operation of a sample dispensing part (20), a reagent dispensing part (26) and a transport arm (24) to deproteinize a sample, wherein the controller (100) is configured to dispense a methanol solution into an empty filtration container (50) to perform a conditioning of a filtration filter (52) disposed in the filtration container (50), then dispense a sample into the filtration container (50), add an acetonitrile solution as a deproteinization agent to the sample in the filtration container (50), and then perform a filtration process in the filtration part (30).

At least one of method information representing an analysis execution method to be used for analysis of a sample and device information for specifying the configuration of an analysis device is acquired as analysis information by an analysis information acquirer. Syringe information for specifying the configuration of a syringe is acquired by a syringe information acquirer. Based on the analysis information and the syringe information, whether the syringe is suitable for analysis of the sample is judged by a judge. The result of judgement by the judge is presented by a presenter.

At least one of method information representing an analysis execution method to be used for analysis of a sample and device information for specifying the configuration of an analysis device is acquired as analysis information by an analysis information acquirer. Syringe information for specifying the configuration of a syringe is acquired by a syringe information acquirer. Based on the analysis information and the syringe information, whether the syringe is suitable for analysis of the sample is judged by a judge. The result of judgement by the judge is presented by a presenter.

In accordance with some embodiments of the present disclosure, a loading tool for a multi-well chromatography filter plate is disclosed. The loading tool may include a top plate and a bottom plate slidably coupled to the top plate. The top plate may include a plurality of wells for holding a material, a rail located along a side of the top plate, and a notch formed in the rail. The bottom plate may include a plurality of funnels extending from the bottom plate, each of the plurality of funnels corresponding to one of the plurality of wells, a track located along a side of the bottom plate to receive the rail located on the top plate, and a pathway formed in the track to receive the notch such that the notch and the pathway limit movement of the top plate relative to the bottom plate.