G01N30/6052

Layered chromatography column cylinder
11224827 · 2022-01-18 · ·

Disclosed is a chromatography column cylinder (200) formed from a polymer composite comprising an outer layer (220) and inner layer (210) intended to be in direct contact with the intended contents of the cylinder in a volume (202), wherein the outer layer supports the inner layer, for example when there is negative pressure in the volume (202). In one embodiment, one of said layers is molded directly onto a surface of the other layer such that there is no gap between the two layers. Disclosed also is a method for forming a chromatography column cylinder.

DEVICES AND SYSTEMS FOR CHROMATOGRAPHY COLUMN BED SUPPORT MANAGEMENT AND RELATED METHODS

Embodiments of the present disclosure may assist in managing, storing, using, and re-using dedicated chromatography column bed supports. For example, devices and systems disclosed herein may include reusable cases for storing dedicated column bed supports when the column bed supports are not in use. Such cases may include one or more dividers and inserts configured to fit column bed supports, and may be designed and built specifically to ensure efficient, secure storage of column bed supports while minimizing risk of damaging or contaminating them. Methods disclosed herein may include performing a particular chromatography operation in a column, removing the column bed supports from the column, storing the column bed supports in a column bed support storage case, and installing another set of column bed supports in the column for another chromatography operation.

Chromatography Apparatus

Disclosed is a chromatography system (100) comprising: plural modules (1-25) including at least one pump and a column valve unit (8) connectable to plural chromatography columns; and a controller (600), the controller being operable to control the or each pump and the column valve to perform different chromatographic processes, including chromatography employing just one column, as well as chromatography employing just one column, as well as chromatography employing two or more columns by selective valve opening in said unit. The system includes a housing (110) into which the plural modules (1-25) are interchangeably mountable in apertures of one generally vertical face of housing, the modules are adapted for selective fluidic interconnection by tubing substantially at said one face such that in use the modules and tubing occupy a generally vertically extending volume to minimize the footprint of the system.

Devices and systems for chromatography column bed support management and related methods

Embodiments of the present disclosure may assist in managing, storing, using, and re-using dedicated chromatography column bed supports. For example, devices and systems disclosed herein may include reusable cases for storing dedicated column bed supports when the column bed supports are not in use. Such cases may include one or more dividers and inserts configured to fit column bed supports, and may be designed and built specifically to ensure efficient, secure storage of column bed supports while minimizing risk of damaging or contaminating them. Methods disclosed herein may include performing a particular chromatography operation in a column, removing the column bed supports from the column, storing the column bed supports in a column bed support storage case, and installing another set of column bed supports in the column for another chromatography operation.

FLAME PROOF ANALYSIS DEVICE BASED ON CHROMATOGRAPHY

The disclosure includes a flame proof analysis device comprising a first chamber. In some embodiments, the flame proof analysis device comprises a power supply unit coupled to the first chamber. According to some embodiments, the flame proof analysis device comprises a chromatograph circuit board coupled to the first chamber. The flame proof analysis device may comprise a communication board coupled to the first chamber. In some embodiments, the flame proof analysis device comprises a control panel coupled to the first chamber. According to some embodiments, the flame proof analysis device comprises a suction pump coupled to the first chamber.

Chromatography cartridge and method of production thereof
11385209 · 2022-07-12 · ·

The present invention relates to a pre-packed chromatography cartridge (10) suitable for flash chromatography. The chromatography cartridge (10) comprises a barrel (20) having one end sealed with a cap (40), a thread (23) arranged on the outer cylindrical surface of the barrel (20) and engaged to a mating thread (43) on the inner cylindrical surface of the cap (40). The barrel is provided with at least one protrusion (24) arranged on the outer cylindrical surface and below the thread (23) in the direction from the end sealed by the cap (40). The protrusion (24) extends essentially radially outwards from the outer cylindrical surface of the barrel (20). The cap (40) is provided with a cylindrical flange (44) arranged below the thread (43) of the cap (40). A locking member (46) is arranged on the flange (44) and extends essentially radially inwards from the inner cylindrical surface of the flange (44). Together with the protrusion (24) of the barrel (20), the locking member (46) forms a mechanical connection that secures the cap (40) such that it cannot be unscrewed from the barrel (20).

System and method for optimizing spray deposition parameters
11302523 · 2022-04-12 · ·

A system for depositing a chemical of one or more components onto a substrate is provided. The system includes a spray assembly for depositing the chemical, a substrate for collecting the one or more components forming the chemical, and an enclosure for housing the substrate and the spray assembly. The spray assembly includes a capillary for receiving and ejecting a fluid containing the one or more components, a nozzle for receiving and ejecting a gas towards both the substrate and the fluid when the fluid is ejected from the capillary, and a spray heater for heating the capillary and the gas. The enclosure includes a translatable drawer for supporting and translating the substrate. The system further includes a substrate heater for heating the substrate.

Monolithic sorbents having a metal cladding
11268938 · 2022-03-08 · ·

The invention relates to monolithic sorbents which are clad with tubes made of metal. The metal cladding can be applied directly to the monolithic sorbents by cold forming. This enables very mechanically stable cladding of the monolithic sorbents with minimal dead space.

METHOD FOR PROVIDING A CASING FOR A CHROMATOGRAPHY COLUMN AND CHROMATOGRAPHY COLUMN

A method for providing a casing (11) for a prefabricated column (1) of chromatography column material in order to manufacture a chromatography column, wherein the casing (11) is generated by additive manufacturing, includes the steps of rotating the column (1) of chromatography column material with respect to a casing material feed in a manner to successively cover a casing surface (8) of the chromatography column material along a contact area path (12), and of arranging an amount of flowable casing material (9) at a current contact area (7) along the contact area path (12) at the casing surface (8) of the column (1) of chromatography column material in order to generate the casing (11) for the chromatography column by successively adding the solidified amount of casing material (9) at the contact area (7).

HEATER INTEGRATED GAS CHROMATOGRAPHY COLUMN DEVICE
20220074898 · 2022-03-10 ·

A heater integrated gas chromatography (GC) column device according to the present invention is capable of precisely and uniformly controlling a temperature by having a high thermal conductivity, and raising and lowering a temperature at a high speed by having a low thermal mass, such that a measuring time is significantly decreased. The GC column is in contact with a bobbin with a homogeneous temperature distribution, and thus a temperature is homogeneously distributed in each GC column. Further, the heater integrated GC column device according to the present invention has the above-described effects and may have a smaller size.