Method for adapting the concentration of a sample gas in a gas mixture to be analysed by a gas chromatograph assembly (10), the gas chromatograph assembly (10) comprising a sample gas inlet (20) for introducing a sample gas to be analysed, a secondary gas inlet (40), a gas chromatograph infrared sensor (12), a gas chromatograph column (26), and a gas chromatograph bypass (28) parallel to the column (26), characterized by a) introducing an amount of sample gas through the sample gas inlet (20), b) introducing an amount of secondary gas through the secondary gas inlet (40), c) mixing the sample gas and the secondary gas to a gas mixture and conducting the gas mixture via the gas chromatograph bypass (28), d) circulating the gas mixture in a gas conducting loop (52) comprising the gas chromatograph bypass (28), the gas chromatograph infrared sensor (12) and not comprising the gas chromatograph column (26), e) analysing the gas mixture thus obtained by means of gas chromatography employing the gas chromatograph column (26) and the gas chromatograph infrared sensor (12).

Method for adapting the concentration of a sample gas in a gas mixture to be analysed by a gas chromatograph assembly (10), the gas chromatograph assembly (10) comprising a sample gas inlet (20) for introducing a sample gas to be analysed, a secondary gas inlet (40), a gas chromatograph infrared sensor (12), a gas chromatograph column (26), and a gas chromatograph bypass (28) parallel to the column (26), characterized by a) introducing an amount of sample gas through the sample gas inlet (20), b) introducing an amount of secondary gas through the secondary gas inlet (40), c) mixing the sample gas and the secondary gas to a gas mixture and conducting the gas mixture via the gas chromatograph bypass (28), d) circulating the gas mixture in a gas conducting loop (52) comprising the gas chromatograph bypass (28), the gas chromatograph infrared sensor (12) and not comprising the gas chromatograph column (26), e) analysing the gas mixture thus obtained by means of gas chromatography employing the gas chromatograph column (26) and the gas chromatograph infrared sensor (12).

A microfluidic device and a method for mixing liquids by moving the liquids back-and-forth between a chamber of a piston pump and a cavity of a spectrophotometric measuring cell. The disclosure also relates to physicochemical analysis of a mixture directly within the microfluidic device wherein the mixture is obtained using the method described herein. The disclosure also relates to a device and a method for sampling liquids remotely.

A microfluidic device and a method for mixing liquids by moving the liquids back-and-forth between a chamber of a piston pump and a cavity of a spectrophotometric measuring cell. The disclosure also relates to physicochemical analysis of a mixture directly within the microfluidic device wherein the mixture is obtained using the method described herein. The disclosure also relates to a device and a method for sampling liquids remotely.

The present disclosure describes a computer implemented method, a system, and a computer program product of controlling the purification of a macromolecule solution via real-time multi-angle light scattering.

The present disclosure describes a computer implemented method, a system, and a computer program product of controlling the purification of a macromolecule solution via real-time multi-angle light scattering.

A chromatography column for the use of separation of acidic sugar chains, wherein the column comprises a first column and a second column, the second column connected by a flow path downstream of an outlet of the first column, and selected from the following (1) or (2): (1) the carrier of the first column is hydrophobically modified silica having a group containing a primary amine, a secondary amine or/and a tertiary amine, and the carrier of the second column is a resin having a group containing a primary amine, a secondary amine or/and a tertiary amine; (2) the carrier of the first column is a resin having a group containing a primary amine, a secondary amine or/and a tertiary amine, and the carrier of the second column is hydrophobically modified silica having a group containing a primary amine, a secondary amine, or/and a tertiary amine.

A chromatography column for the use of separation of acidic sugar chains, wherein the column comprises a first column and a second column, the second column connected by a flow path downstream of an outlet of the first column, and selected from the following (1) or (2): (1) the carrier of the first column is hydrophobically modified silica having a group containing a primary amine, a secondary amine or/and a tertiary amine, and the carrier of the second column is a resin having a group containing a primary amine, a secondary amine or/and a tertiary amine; (2) the carrier of the first column is a resin having a group containing a primary amine, a secondary amine or/and a tertiary amine, and the carrier of the second column is hydrophobically modified silica having a group containing a primary amine, a secondary amine, or/and a tertiary amine.

Methods for determining the relative abundance of intact adeno-associated virus (AAV) capsid components in a sample of recombinant AAV particles are disclosed. In embodiments, the methods include a system regeneration process that minimizes or eliminates the presence of ghost peaks to maximize analytical accuracy and ensure product quality and consistency.

Methods for detecting cancer cells, or aggressive cancers, by measuring levels of cardiolipin molecules are provided. Methods of treating identified cancers are likewise provided.