A gas analysis device suited for e.g. medical analysis of exhaled breath from a subject. A gas inlet receives a gas sample to a flow path for guiding the gas sample to two or more gas separators, e.g. gas chromatography columns, with respective molecule selectivity properties which are different. One or more detectors, each with a sensor, are arranged to generate respective responses to outputs from the two or more gas separators. A communication module generate output data in response to the respective responses from the one or more detectors, e.g. data indicative of selected molecules in the gas sample, e.g. data indicative of one or more diseases identified as a result of identified biomarkers in the gas sample. The device is suitable as a compact device, e.g. a handheld breath analysis device, since the use of a plurality of gas separators allows use of very molecule specific gas separators which can be implemented with a small size. E.g. a flow path with several parallel paths each comprising one or more gas separator may be used.

A gas analysis device suited for e.g. medical analysis of exhaled breath from a subject. A gas inlet receives a gas sample to a flow path for guiding the gas sample to two or more gas separators, e.g. gas chromatography columns, with respective molecule selectivity properties which are different. One or more detectors, each with a sensor, are arranged to generate respective responses to outputs from the two or more gas separators. A communication module generate output data in response to the respective responses from the one or more detectors, e.g. data indicative of selected molecules in the gas sample, e.g. data indicative of one or more diseases identified as a result of identified biomarkers in the gas sample. The device is suitable as a compact device, e.g. a handheld breath analysis device, since the use of a plurality of gas separators allows use of very molecule specific gas separators which can be implemented with a small size. E.g. a flow path with several parallel paths each comprising one or more gas separator may be used.

A controller includes a temperature prediction unit. The temperature prediction unit predicts, on the assumption that a refrigerant is fed from a refrigerant feeder, an internal temperature of a column oven based on time interval information and decrement information in a memory. Thus, the temperature prediction unit can accurately predict the internal temperature of the column oven when the refrigerant is fed from the refrigerant feeder. If the refrigerant is fed from the refrigerant feeder when the predicted internal temperature of the column oven is suitable for the analysis operation, the internal temperature of the column oven can be brought closer to an appropriate temperature. As a result, the internal temperature of the column oven can be controlled with precision.

A controller includes a temperature prediction unit. The temperature prediction unit predicts, on the assumption that a refrigerant is fed from a refrigerant feeder, an internal temperature of a column oven based on time interval information and decrement information in a memory. Thus, the temperature prediction unit can accurately predict the internal temperature of the column oven when the refrigerant is fed from the refrigerant feeder. If the refrigerant is fed from the refrigerant feeder when the predicted internal temperature of the column oven is suitable for the analysis operation, the internal temperature of the column oven can be brought closer to an appropriate temperature. As a result, the internal temperature of the column oven can be controlled with precision.

A gas chromatography instrument comprising a first autoinjector in communication with a first column, a second autoinjector in communication with a second column, a first flame ionization detector in communication with the first column, a second flame ionization detector in communication with the second column, wherein the first column is housed in a first compartment and the second column is housed in a second compartment.

The present disclosure provides systems and methods that allow users to quickly determine titer and remove hold steps by determining a first concentration using slope spectroscopy, depleting the fluid of the expressed protein by selective adsorption, and determining a second concentration using slope spectroscopy. Further, the systems and methods of the present disclosure allows the user to forgo the use of a bioanalyzer or HPLC.

A modular gas detection system includes a primary gas chromatograph, a constant volume extractor positionable to provide a continuous fluid sample to the primary gas chromatograph, and a total hydrocarbon analyzer. The modular gas detection system also includes a processing device and a memory device including instructions executable by the processing device for causing the processing device to perform operations. The operations include adjusting a detection scheme of the primary gas chromatograph to update a detection range for the continuous fluid sample to detect different hydrocarbons within a single column. Further, the operations include controlling routing of the continuous fluid sample from the constant volume extractor to the primary gas chromatograph and the total hydrocarbon analyzer.

A modular gas detection system includes a primary gas chromatograph, a constant volume extractor positionable to provide a continuous fluid sample to the primary gas chromatograph, and a total hydrocarbon analyzer. The modular gas detection system also includes a processing device and a memory device including instructions executable by the processing device for causing the processing device to perform operations. The operations include adjusting a detection scheme of the primary gas chromatograph to update a detection range for the continuous fluid sample to detect different hydrocarbons within a single column. Further, the operations include controlling routing of the continuous fluid sample from the constant volume extractor to the primary gas chromatograph and the total hydrocarbon analyzer.

The invention relates to a method for the identification of an analyte in a sample fluid. The method comprises the performance of a set of measurements on at least two sensors of different types. Sensors of different types may comprise Gas Chromatography sensors, CMOS gas sensors, a combination thereof, or more generally sensors in which it is possible to control a first physical parameter and measure, for different values of the first parameter, a second physical parameter representative of at least a concentration of the analyte. The method comprises the detection of maxima of the second parameter, the access to databases in order to find reference values of the first parameters in which maxima are found, and the comparison of values at which maxima are found and reference values, on the two sensors.

The invention relates to a method for the identification of an analyte in a sample fluid. The method comprises the performance of a set of measurements on at least two sensors of different types. Sensors of different types may comprise Gas Chromatography sensors, CMOS gas sensors, a combination thereof, or more generally sensors in which it is possible to control a first physical parameter and measure, for different values of the first parameter, a second physical parameter representative of at least a concentration of the analyte. The method comprises the detection of maxima of the second parameter, the access to databases in order to find reference values of the first parameters in which maxima are found, and the comparison of values at which maxima are found and reference values, on the two sensors.