Embodiments of a gas detector with a first gas sensor having a first gas specificity and a first response time and a second gas sensor having a second gas specificity and a second response time. The first gas specificity is different than the second gas specificity, the first response time is different than the second response time, or both the first gas specificity and the first response time are different than the second gas specificity and the second response time. A readout and analysis circuit is coupled to the first and second gas sensors to read and analyze data from the first and second gas sensors, and a control circuit is coupled to the readout and analysis circuit and to the first and second gas sensors to execute logic that operates the first gas sensor, the second gas sensor, or both the first and second gas sensors.

A method to filter out pump pulses from data collected with a chromatography system is disclosed. Baseline data is collected as a pump delivers solvent to an analytical instrument, which may be the IP signal of a capillary bridge viscometer. A Fourier transform is applied to the data to generate the power spectrum of the baseline signal. Fundamental and harmonic frequencies are determined and a comb filter is constructed therefrom and applied to sample collected from all of the affected instruments. The comb filter may be correlated to the pump and flow rate and stored in data analysis software or database. Other systems using other pumps may also generate associated comb filters, and the resulting filters and the flow rates at which they were generated may be stored in a database accessible to the data analysis software.

A method to filter out pump pulses from data collected with a chromatography system is disclosed. Baseline data is collected as a pump delivers solvent to an analytical instrument, which may be the IP signal of a capillary bridge viscometer. A Fourier transform is applied to the data to generate the power spectrum of the baseline signal. Fundamental and harmonic frequencies are determined and a comb filter is constructed therefrom and applied to sample collected from all of the affected instruments. The comb filter may be correlated to the pump and flow rate and stored in data analysis software or database. Other systems using other pumps may also generate associated comb filters, and the resulting filters and the flow rates at which they were generated may be stored in a database accessible to the data analysis software.

A diagnostic apparatus for analysing a sample to diagnose disease, the apparatus comprising: a separating element for separating gas derived from the sample into component parts; a sensor arrangement coupled to the separating element such that a component part of the gas is directed towards the sensor arrangement, the sensor arrangement being configured to detect compounds which may be indicative of disease; and a processing element coupled to an output of the sensor arrangement, the processing element being configured to process a signal output by the sensor arrangement to provide a diagnosis.

A diagnostic apparatus for analysing a sample to diagnose disease, the apparatus comprising: a separating element for separating gas derived from the sample into component parts; a sensor arrangement coupled to the separating element such that a component part of the gas is directed towards the sensor arrangement, the sensor arrangement being configured to detect compounds which may be indicative of disease; and a processing element coupled to an output of the sensor arrangement, the processing element being configured to process a signal output by the sensor arrangement to provide a diagnosis.

An analysis method for mycotoxins including a separation step, a detection step, and an identification step. In the separation step, each component contained in a liquid sample is separated in a column In the detection step, components separated in the separation step are detected by a PDA and a fluorescence detector. In the identification step, total aflatoxin is identified based on a detection signal from the fluorescence detector, and deoxynivalenol is identified based on a detection signal from the PDA.

An analysis method for mycotoxins including a separation step, a detection step, and an identification step. In the separation step, each component contained in a liquid sample is separated in a column In the detection step, components separated in the separation step are detected by a PDA and a fluorescence detector. In the identification step, total aflatoxin is identified based on a detection signal from the fluorescence detector, and deoxynivalenol is identified based on a detection signal from the PDA.

In one embodiment, an improved gas analysis system having a gas flow cell is provided. In another embodiment an improved gas flow cell is provided. As disclosed herein, dead volumes in a gas flow channel of a gas flow cell may be minimized through the use of one or more additional gas inlets. In one embodiment, an additional gas inlet is located between an analyte gas inlet and a light entrance optical coupling of the gas flow cell. In another embodiment, an additional gas inlet is located between an analyte gas outlet and a light exit optical coupling of the gas flow cell. In addition, enclosed regions may be formed adjacent seals of the gas flow channel of the gas flow cell. The enclosed regions may be evacuated and/or purged so as to minimize the passage of contaminants through the seals into the gas flow channel.

In one embodiment, an improved gas analysis system having a gas flow cell is provided. In another embodiment an improved gas flow cell is provided. As disclosed herein, dead volumes in a gas flow channel of a gas flow cell may be minimized through the use of one or more additional gas inlets. In one embodiment, an additional gas inlet is located between an analyte gas inlet and a light entrance optical coupling of the gas flow cell. In another embodiment, an additional gas inlet is located between an analyte gas outlet and a light exit optical coupling of the gas flow cell. In addition, enclosed regions may be formed adjacent seals of the gas flow channel of the gas flow cell. The enclosed regions may be evacuated and/or purged so as to minimize the passage of contaminants through the seals into the gas flow channel.

The present disclosure relates to an enhanced multi-dimensional chromatography system and method using selectable At-Column Dilution to improve compatibility of the interface and transfer between the multiple dimensions. The use of At-Column Dilution (ACD) with multi-dimensional chromatography can provide greater retention of the diverted components on subsequent stationary phases, and increase the sensitivity and peak shape of the component(s) separated on subsequent dimensions.