The present invention relates to compositions comprising: a polypeptide, wherein at least a portion of the polypeptide has a coiled coil structure; and a chelate comprising a chelating agent and a metal ion; and wherein the chelate is bound to at least one amino acid of the polypeptide. In a preferred embodiment the polypeptide is a silk fibroin, wherein at least a portion of the silk fibroin has a coiled coil structure.

The present invention relates to a flow wrapper which comprises a form and/or film tube, which forms the planar film into a film tube and/or fills the film tube with a packaging item and which comprises means to provide a longitudinal- and/or cross-seal to the film tube.

There is disclosed a method of calibrating a gas sensor comprising a luminescent compound having a luminescence lifetime that is quenched by a gaseous substance which uses a model of the relationship between the luminescence lifetime and the concentration of the gaseous substance that is modified by a calibration factor representing a proportion of the compound not being exposed to the gaseous substance, the method comprising: measuring values of the luminescence lifetime of the luminescent compound while the gas sensor is exposed to at least two known concentrations of the gaseous substance; and deriving the calibration factor from the measured values of the luminescence lifetime using the model. Also disclosed are a corresponding gas sensor apparatus for measuring the concentration of a gaseous substance in an environment, and method of measuring a concentration of a gaseous substance in an environment using a gas sensor.

A tactical chemical detector may include a light array comprising a plurality of light sources; a sensor optic comprising a plurality of optic elements, each optic element in optical communication with one of the plurality of light sources; a sensor array comprising a plurality of sensors arranged on a substrate, each sensor in optical communication with one of the plurality of light sources and wherein at least one vent opening extends through the substrate; a power source configured to selectively provide power the light array and the sensor array; and a housing having a first side and a second side and enclosing the light array, the sensor optic, the sensor array, and the power source.

To provide: a composition for oxygen detection, which has excellent oxygen detection characteristic (ability), and which is safer than conventional compositions for oxygen detection, thereby being able to be sealed in packages containing food, pharmaceutical products or the like without anxiety; and an oxygen detector onto which this composition for oxygen detection is applied or printed. This composition for oxygen detection contains a redox dye, a food dye, a reducing sugar, an edible reduction promoter and an edible humectant in the composition, and enables quick detection of the presence or absence of oxygen by means of color change. Since this composition for oxygen detection is composed only of food, a pharmaceutical product and edible components allowed to be used for the food or pharmaceutical product, this composition for oxygen detection is safe to the human body.

An anthraquinone compound of formula I (such as the compounds of formulae II to X) and processes for making the same are provided. Pharmaceutical compositions for use in the treatment of cancer, optionally in combination with an agent capable of reducing the level of oxygenation of a tumour, are also provided. Additionally, an option for combination with chemotherapeutic and radiotherapeutic modalities to enhance overall tumour cell kill is provided. Methods for the detection of cellular hypoxia, both in vivo and in vitro, are additionally provided.

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An oxygen content sensor includes a nanoparticle, a plurality of linkers, and a plurality of fluorescent molecules. The linkers are disposed on the nanoparticle. The fluorescent molecules are arranged on the linkers. The linker has at least a hydrophilic region as well as a hydrophobic region. The linker is linked to the nanoparticle through the hydrophilic region, and the fluorescent molecule is linked to the linker through the hydrophobic region.

A capsule suitable for oxygen and temperature sensing contains: i) at least one first sensitizer compound being capable of energy transfer to triplet oxygen, ii) at least one compound being capable of reacting with and inactivating singlet oxygen, iii) at least one second sensitizer compound being capable of absorbing radiation at a second frequency v.sub.2 and of emitting light at a fourth frequency v.sub.4, iv) at least one emitter compound, wherein the at least one second sensitizer compound is capable of transferring energy to the at least one emitter compound and wherein the at least one emitter compound, after obtaining energy transferred from the at least one second sensitizer compound, is capable of emitting light at a third frequency v.sub.3, wherein the following equation is fulfilled: v.sub.3>v.sub.2,
wherein the upper energy limit of the first triplet energy band of the first sensitizer compound is lower than the lower energy limit of the second triplet energy band of the second sensitizer compound and lower than the lower energy limit of the third triplet energy band of the emitter compound, and wherein the third triplet band of the emitter compound at least partially overlaps with the second triplet energy band of the second sensitizer compound.

An optical sensor (1) for detecting a chemical species includes a substrate (3), a mesoporous matrix (5) disposed on the substrate, and a microporous matrix (7) disposed within the mesoporous matrix. The microporous matrix (7) includes an indicator dye (9) dispersed therein, the indicator dye (9) exhibiting changes in its optical properties in response to the presence of the chemical species. This arrangement significantly increases the amount of dye present, while allowing the medium to be analyzed greater access through the porous structure, thereby increasing the performance of the sensor.

To provide a display medium that is discolored in a state of being exposed in the presence of oxygen. This display medium has a discoloration layer on a substrate, the discoloration layer being formed with a redox dye, a food dye, a reducing sugar, an edible reduction promoter, an edible moisturizer, and an oxygen detection composition that contains an edible thickener. The oxygen detection composition that forms the discoloration layer is reversibly discolored in accordance with the presence of oxygen, so that the discoloration layer changes color upon transition from an oxygen-free state to an oxygen-present state. Therefore, when the discoloration layer is formed with a letter, a drawing pattern, a symbol or the like, information relating to a commodity constituted by the letter, drawing pattern, symbol or the like is highlighted by discoloration.