Optical tomography arrangements are disclosed for performing optical tomography on the transparent or translucent contents of individual microplate wells comprising a light emitting array having a plurality of light emitting elements, a sample module, and a light sensing array including a plurality of light sensing elements, wherein the light sensing array is configured to sense light emitted from the light emitting array which has passed through the sample module. The light emitting elements can comprise light emitting diodes (LEDs), organic light emitting diodes (OLEDs), organic light emitting transistors (OLETs), and/or other optoelectronic devices. The light sensing array can comprise organic light sensing devices, photodiodes, phototransistors, CMOS photodetectors, or charge-coupled devices (CCDs). The light emitting array can be flat or curved, and the light sensing array can be flat or curved. The collection of measurement values can be overspecified, and a generalized inverse operation can provide solutions rendering computational tomography data.

The invention relates to a device (100) and a corresponding method for thermoacoustic sensing, in particular thermoacoustic imaging, the device (100) comprising: a) an irradiation unit (10) configured to generate electromagnetic and/or particle energy exhibiting a first modulation, the first modulation comprising at least one frequency and to continuously emit the energy towards a target (1), whereby acoustic waves are continuously generated in the target, the acoustic waves exhibiting a second modulation, the second modulation comprising the at least one frequency and/or a harmonic frequency of the at least one frequency; b) a detection unit (20) configured to simultaneously detect the acoustic waves exhibiting the second modulation while the energy exhibiting the first modulation is being continuously emitted towards the target (1); and c) a processing unit (30) configured to determine at least one thermoacoustic value of an amplitude and/or a phase of the second modulation of the acoustic waves at the at least one frequency and/or at a harmonic frequency of the at least one frequency. The invention allows for fast and economic thermoacoustic sensing, in particular imaging of a region of interest of an object.

A device for measuring radiation backscattered by a sample including: at least one light source that is configured to emit a light beam, along an axis of incidence, towards a surface of the sample so as to form, on said surface, an elementary illumination zone; an image sensor for forming an image of the radiation backscattered by the sample when the latter is illuminated by the light source, the image sensor lying in a detection plane; a bundle of optical fibres, extending, along an extension axis, between a proximal surface and a distal surface, the proximal surface being applied against the image sensor, the distal surface being configured to be applied against the surface of the sample;
wherein the light source is arranged around the bundle of optical fibres, and wherein the distance between the light source and the bundle of optical fibres is less than 1 mm.

The present invention discloses a monolithic integration device and micro Total Analysis System. The monolithic integration device for sensing comprises: a micro-LED; an optical detector; and a sensing channel, wherein the micro-LED is coupled with the sensing channel and is configured for emitting light into the sensing channel, and the optical detector is coupled with the sensing channel and is configured for sensing the light which is emitted by the micro-LED and travels through at least one part of the sensing channel. An embodiment of this invention proposes a new monolithic integration device for sensing with built-in light source and optical detection system.

A device for optical detection of analytes in a sample includes at least two optoelectronic components. The optoelectronic components include at least one optical detector configured to receive a photon and at least one optical emitter configured to emit a photon. The at least one optical emitter includes at least three optical emitters disposed in a flat, non-linear arrangement, and the at least one optical detector includes at least three optical detectors disposed in a flat, non-linear arrangement. The at least three optical emitters and the at least three optical detectors include at least three different wavelength characteristics.

A device and a method for foam analysis. The device comprises a cylindrical sample container with a transparent wall, at least one illumination device and a camera, which. can be moved on a track. The curvature of the web runs parallel to the wall of the container. The illumination device directs a light beam onto the wall of the cylindrical sample container at an angle which deflects the light beam into the sample vessel when liquid is present on the inside of the sample container and causes a total reflection when air or another gas fills the foam pores. The camera and the illumination unit are moved along the path in the circumferential direction of the wall of the sample container such that a region to be examined is illuminated in steps or in a continuous progression and the camera records the totally reflected light in the region.

This invention relates generally to devices, systems, and methods for performing biological assays by using indicators that modify one or more optical properties of the assayed biological samples. The subject methods include generating a reaction product by carrying out a biochemical reaction on the biological sample introduced into a device and reacting the reaction product with an indicator capable of generating a detectable change in an optical property of the biological sample to indicate the presence, absence, or amount of analyte suspected to be present in the sample.

An image forming apparatus includes an optical sensor configured to detect an image formed on an intermediate transfer belt. The optical sensor includes a first LED, a second LED, a first PD, and a second PD on a substrate. The first PD is arranged at a position at which specularly reflected light of light emitted from the first LED can be received, and scattered reflected light of light emitted from the second LED can be received. The second PD is arranged at a position at which scattered reflected light of light emitted from the second LED can be received. A light receiving surface of the first PD and a light receiving surface of the second PD are formed at different angles. The light receiving surface of the first PD has an area that is smaller than an area of the light receiving surface of the second PD.

A quality control station (2) for a sheet element processing machine, having at least one camera (6) arranged for capturing images of sheet elements (4) transported through the quality control station (2), and further having an illumination unit (5) with at least one light emitter (16) and two reflectors (12, 14), the illumination unit (5) directing light onto a viewing area of the camera (6) such that the illumination intensity is constant despite changing media thickness. An illumination unit for such quality control station is disclosed.

A method for optically inspecting a mold (10) for manufacturing ophthalmic lenses such as contact lenses for possible mold defects, including: generating a set of images of the mold (10) for different azimuthal illumination angles (1, 9) using an illumination system (20) and an imaging system (30), the latter being aligned such that its focal plane cuts through the mold (10) at a specific axial position along a center axis of the mold (10); generating a focal plane image by averaging pixelwise over the set of images after having masked out in each image those regions that include direct specular reflections from the mold (10); repeating the previous steps for one or a plurality of different axial positions of the focal plane such as to generate a plurality of different focal plane images; identifying one or more image features in the plurality of focal plane images indicative for a possible mold defect; determining for each identified image feature in which focal plane image the identified image feature appears sharpest; generating for each identified image feature a respective image section out of the respective sharpest focal plane containing the image feature; and generating a composed dark field image of the mold (10) by composing the respective image sections for each identified image feature, thus enabling to determine as to whether the possible defects of the mold (10) still allow the mold (10) to be used.