Patent classifications
G01N2201/0626
MULTI-COLOR FLUORESCENT EXCITATION AND DETECTION DEVICE AND NUCLEIC ACID ANALYSIS APPARATUS EMPLOYING SAME
A multi-color fluorescent excitation and detection device comprises at least one illumination module, a cartridge and at least one detection module. The illumination module provides an illumination light at specified range of wavelengths. The cartridge comprises a detection chip comprising plural detection wells arranged around the peripheral of the detection chip. The detection chip is circular shape. Each of the detection wells is accommodated a corresponding fluorescent dye therein. Each of the detection wells includes a first wall and a second wall. The illumination light transmits through the first wall to illuminate on the fluorescent sample so as to excite a fluorescent signal, and the fluorescent signal generated from the fluorescent sample transmits through the second wall. The detection module receives the fluorescent signal and convert the fluorescent signal to an electrical signal.
Cylindrical optical tomography for microscopy, cell cytometry, microplate array instrumentation, crystallography, and other applications
A cylindrical optical tomography system includes a light emitting array having a plurality of light emitting elements, a cylindrical sample holding element, and a light sensing array including a plurality of light sensing elements, wherein the light sensing array is configured to sense light emitted from the light emitting array which has passed through the sample holding module.
OPTICAL DETECTION DEVICE, ITS METHOD FOR OPERATING AND COMPUTER PROGRAM
The invention relates to a light emitting device comprising a light source array which comprises a plurality of separately electrically controllable electric light sources which are arranged in a matrix structure or any other defined geometrical arrangement. Advantageously, the pixel pitch of the light source array is less than (500) nanometer. The invention further relates to an optical detection device comprising a light detection device, which is arranged for producing an electrical signal in response to light reaching a light detection side of the light detection device, and to a method for operating such an optical detection device. The invention further relates to a computer program with program coding means arranged for performing such a method.
ILLUMINATION SYSTEM FOR RECOGNIZING MATERIAL AND METHOD OF RECOGNIZING MATERIAL USING THE SAME
An illumination system for recognizing material includes a measurement stage, a light-providing part, a light-receiving part, and a processing part. The measurement stage is upwardly open and the measurement target is located on the measurement stage. The light-providing part includes a plurality of illumination sections providing incident lights to the measurement target, and provides multi-directional incident lights to the measurement target from multiple upper directions at which the measurement stage is open. The light-receiving part receives single-directional reflection lights reflected by the measurement target according to the multi-directional incident lights provided by the light-providing part. The processing part acquires a multi-directional intensity distribution of multi-directional reflection lights reflected by the measurement target according to a single-directional incident light from the single-directional reflection lights reflected by the measurement target according to the multi-directional incident lights, and determines material of the measurement target from the multi-directional intensity distribution of reflection lights. Thus, material of an object may be easily and accurately known at a low cost.
SCREENING SYSTEM TO IDENTIFY PATHOGENS OR GENETIC DIFFERENCES
A system for screening of pathogens or gene differences includes first and second screening modes and a source of electromagnetic radiation for illuminating a plurality of samples. The source of electromagnetic radiation has a selectable illumination property. The system also may include a detector for detecting electromagnetic radiation transmitted through or emitted by the plurality of samples with the detector having a selectable detection property. The system may be arranged for concurrent operation in the first and the second mode. The first screening mode may be a fluorometric screening mode and the second optional screening mode may be a colorimetric screening mode.
Multiplexed biological assay device with electronic readout
This invention relates generally to devices, systems, and methods for performing biological assays by using indicators that modify one or more optical properties of the assayed biological samples. The subject methods include generating a reaction product by carrying out a biochemical reaction on the biological sample introduced into a device and reacting the reaction product with an indicator capable of generating a detectable change in an optical property of the biological sample to indicate the presence, absence, or amount of analyte suspected to be present in the sample.
Cylindrical Optical Tomography for Microscopy, Cell Cytometry, Microplate Array Instrumentation, Crystallography, and Other Applications
A cylindrical optical tomography system includes a light emitting array having a plurality of light emitting elements, a cylindrical sample holding element, and a light sensing array including a plurality of light sensing elements, wherein the light sensing array is configured to sense light emitted from the light emitting array which has passed through the sample holding module.
Apparatus for measuring multi-wavelength transmittance using learned LED temperature compensation model
A device to measure the amount of light able to transmit through a liquid. The device uses a light detector and multiple light emitting diodes (LED's) along with an optical unit such that the light detector, LED's, and an optical unit define a path of light emitted by each individual LED or subgroup of LED's and detected by the detector. The device uses a structure designed to surround the LED's and light detector such that the structure allows the device to be immersed in the liquid and such that the structure is shaped to allow a volume of liquid to be between the LED's and detector, intersecting the light path.
WEARABLE DEVICE FOR DIFFERENTIAL MEASUREMENT ON PULSE RATE AND BLOOD FLOW
A wearable device to measure a user's physiological parameters comprising one or more biosensors, as well as a light source comprising light emitting diodes, lenses for directing light towards tissue of the user comprising blood vessels, and a detection system receiving reflected tissue light. The physiological parameters, for example hypertension, are measured with a differential measurement. For example, the physiological parameters may be associated with pulse rate and blood flow. The output signal is associated with the physiological parameters, and artificial intelligence may be used in making decisions regarding the output signal. Signal-to-noise ratio of the output signal may be improved by synchronizing the detection system to the light source, increasing light intensity, and detecting a change. The wearable device is configured to determine that is being worn by the user and may be configured to communicate with a smartphone or tablet.
SENSOR DEVICE FOR HIGH-RESOLUTION DETECTION OF TARGET SUBSTANCES
An optical sensor device which measures in a spatially resolving manner is disclosed. In order to devise such a sensor device with which a contacting measurement of the article to be measured can be carried out and which can be mass-produced, the sensor device is designed such that a transfer of the calibration onto individual sensor devices is possible with high accuracy. According to certain embodiments of the design of the sensor device and of the evaluation methods, interferences with the measurement of the amount of the target substance are minimized