In a method for determining imaging parameters for a Magnetic Resonance (MR) image, a set of image sequence parameters of the imaging sequence is determined, a frequency offset of off-resonant tissue potentially present in the object under examination is determined, an allowed maximum position shift of the off-resonant tissue along a slice selection direction is determined, a rotation angle which leads to the allowed maximum shift for the off-resonant tissue is determined based on the determined set of image sequence parameters, and the determined rotation angle is provided to the MR imaging system to allow the MR imaging system to generate the MR image using the determined rotation angle in the imaging sequence.

The devices, systems, and methods can improve magnetic resonance imaging (MRI), MR spectroscopy (MRS), MR spectroscopic imaging (MRSI) measurement(s), thereby providing more reliable quantification. The method may include a method for correcting MR image(s)/spectrum. The method may include providing an inhomogeneity field/response map of a region of interest; and providing MR image(s)/spectrum of the region of interest. The method may include determining an intravoxel/voxel inhomogeneity correction coefficient for each voxel of at least one subregion of the region of the interest using the inhomogeneity field/response map. The method may include correcting each voxel of the MR image(s)/spectrum of the region of interest using the intravoxel/voxel inhomogeneity correction coefficient. The MR image(s)/spectrum may include chemical exchange saturation transfer (CEST)/magnetization transfer (MT) imaging with Z-spectrum, CEST/MT imaging without Z-spectrum, CEST spectroscopy, CEST MRS, MRS, MRSI, or any combination thereof.

A system and method for simulating the spatial and temporal magnetic properties of configurable nanoscale magnetic molecules is provided comprising steps for simulating molecular spintronics devices (MSD) of different shapes involving thousands of magnetic atoms and molecules, representing complex magnetic molecules as a device element in MSD to use MCSMSD, defining a wide range of magnetic molecule-magnetic electrode interactions in MSD, studying the magnetic anisotropy effect in MSD simulation, studying the effect of electrons in the magnetic electrodes and fluctuations controlling the active molecule population in MSD simulation, studying the effect of defects within insulator competing with magnetic molecules, and harnessing parallel processing capabilities in desktop computers.

A B.sub.0-mapping method determines the spatial distribution of a static magnetic field in a pre-selected imaging zone comprising computation of the spatial distribution of a static magnetic field from a spatial distribution of spin-phase accruals between magnetic resonance echo signals from the imaging zone and an estimate of the proton density distribution in the imaging zone. The invention provides the field estimate also in cavities and outside tissue. Also the field estimate of the invention suffers less from so-called phase-wraps.

An Optically Pumped Magnetometer (OPM) system is configured to characterize a magnetic field. The OPM system comprises an OPM sensor that is coupled to an OPM cable that is coupled to an OPM connector that is detachably coupled to an OPM controller. The OPM connector stores OPM operational data. The OPM controller reads the OPM operational data when the OPM connector is coupled to an OPM controller. The OPM controller generates sensor control signals based on the OPM operational data and transfers the control signals to the OPM sensor. The OPM sensors characterize the magnetic field in response to the sensor control signals and transfer output signals that characterize the magnetic field to the OPM controller. The OPM controller models the magnetic field based on the output signals and transfers new OPM operational data to OPM connector. The OPM connector stores the new OPM operational data in the memory.

A system and method are provided for producing at least one of an image or a map of a subject includes controlling a magnetic resonance imaging (MRI) system to perform a pulse sequence that includes a phase increment of an RF pulse selected to induce a phase difference between two echoes at different echo times (TE). The method also includes controlling the MRI system to acquire MR data corresponding to at least the two echoes at different TEs, deriving a static magnetic field (B0) map of the MRI system using the MR data corresponding to the two echoes, and using the B0 map and MR data from at least one of the two echoes, generate a map of T2 of the subject.

A method is provided for homogenizing a magnetic field profile of a superconductor magnet system having a cryostat with a room temperature bore, a superconductor bulk magnet with at least three axially stacked bulk sub-magnets, arranged coaxially with the room temperature bore, and a cryogenic cooling system for cooling the superconductor bulk magnet. The cryogenic cooling system independently controls the temperature of each bulk sub-magnet to provide different respective temperatures to the sub-magnets and thereby provide the sub-magnets with different relative currents such that a first subset of the bulk sub-magnets are almost magnetically saturated, and a second subset of the bulk sub-magnets are significantly away from magnetic saturation. By controlling a heating power and/or a cooling power at the bulk sub-magnets without measuring the temperatures of the bulk sub-magnets, the respective currents of the bulk sub-magnets are changed to increase a homogeneity of the field profile.

An imaging system and method are disclosed. An MR image and measured B0 field map of a target volume in a subject are reconstructed, where the MR image includes one or more bright and/or dark regions. One or more distinctive constituent materials corresponding to the bright regions are identified. Each dark region is iteratively labeled as one or more ambiguous constituent materials. Susceptibility values corresponding to each distinctive and iteratively labeled ambiguous constituent material is assigned. A simulated B0 field map is iteratively generated based on the assigned susceptibility values. A similarity metric is determined between the measured and simulated B0 field maps. Constituent materials are identified in the dark regions based on the similarity metric to ascertain corresponding susceptibility values. The MRI data is corrected based on the assigned and ascertained susceptibility values. A diagnostic assessment of the target volume is determined based on the corrected MRI data.

According to one aspect of the invention, there is provided a method of constructing a diagnostic image of a sample from MRI data acquired while subjecting the sample to an inhomogeneous polarizing magnetic field, the method comprising the steps of: i) deriving an estimate of the spatial map of the inhomogeneous polarizing magnetic field; ii) acquiring the MRI data; iii) processing the estimate of the spatial map with the acquired MRI data to obtain an estimate of the diagnostic image; iv) calculating an acquired data error in response to the estimates of the spatial map and the diagnostic image; v) updating the estimate of the spatial map in response to the calculated error; and repeating the steps iii) to v) to improve the estimate of the spatial map of the earlier iteration and the estimate of the diagnostic image, wherein the repetition is stopped when the calculated error of the latest iteration reaches within a tolerance range and wherein the estimate of the diagnostic image from the latest iteration becomes the diagnostic image of the sample.

A magnetic field measuring device includes: a first cell and a second cell in which alkali metal atoms are entrapped and which are disposed in this order in a sensing direction of a magnetic field; a first reflective mirror, a second reflective mirror, and an autocollimator as an optical axis detector. Beam light as second polarized light and beam light as fourth polarized light, which are detected by the autocollimator, have orientations of optical axes in the same direction.