A method, including subjecting a subcutaneous medical device containing a magnet to a magnetic field, thereby imparting a torque onto the magnet, and resisting the imparted torque via an external device that has a skin facing component extending in a direction away from a curvature of the body of the recipient at locations proximate a portion directly contacting skin directly above the implanted magnet.

This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient.

A method for operating a magnetic resonance apparatus by a safety unit, taking into account persons fitted with an implant, a safety unit, a safety system, a magnetic resonance apparatus, and a computer program product are provided. The magnetic resonance apparatus includes a first part and a second part. The first part is operated separately from the second part and includes the safety unit. During an examination of a person fitted with an implant, the safety unit checks that the magnetic resonance apparatus, in a restricted operating mode, is complying with implant-conformant limit values.

In an embodiment, a method for effecting thermal therapy using an in vivo probe includes positioning the probe in a volume in a patient, identifying an irregularly shaped three-dimensional region of interest and automatically applying thermal therapy to the region using the probe. Applying thermal therapy may include identifying a first emission level at a first rotational angle based in part on a depth of a radial portion of the region in the direction of probe emission, activating emission of the probe, causing rotation of the probe to a next rotational angle, identifying a next emission level at the next rotational angle based in part on a depth of a radial portion of the region in the direction of probe emission, activating emission to deliver therapeutic energy, and repeating rotation and emission until therapeutic energy has been delivered to the volume.

Systems and methods for transferring fluid to or from a subject use a set of MRI compatible components that can aspirate intrabody structure and/or fluids. The components include a device guide, a semi-rigid guide sheath configured to slidably extend through the device guide, a stylet releasable coupled to the guide sheath and extending a fixed distance out of a distal end thereof, and a cannula coupled to flexible tubing that is releasably interchangeably held in the guide sheath in lieu of the stylet.

A delta-relaxation magnetic resonance imaging (DREMR) system is provided. The system includes a main field magnet and field shifting coils. A main magnetic field with a strength B0 can be generated using the main filed magnet and the strength B0 of the main magnetic field can be varied through the use of the field-shifting coils. The DREMR system can be used to perform signal acquisition based on a pulse sequence for acquiring at least one of T2*-weighted signals imaging; MR spectroscopy signals; saturation imaging signals and MR signals for fingerprinting. The MR signal acquisition can be augmented by varying the strength B0 of the main magnetic field for at least a portion of the pulse sequence used to acquire the MR signal.

An intravascular MRI probe assembly for producing real time, three dimension imagery of an interior of a blood vessel includes a probe has diameter is sufficiently small to fit inside of a blood vessel of a human being. An x coil, a y coil and a pair of z coils is each positioned within the probe for producing a magnetic field to facilitate magnetic resonance imaging of an interior of the blood vessel. A first gradient echo coil, a second gradient coil, a shim coil and a magnet is each positioned within the probe. A conductor is coupled to the probe and the conductor extends away from the second end of the probe. Additionally, the conductor is electrically coupled to a magnetic resonance imaging processor to produce a three dimensional image of the interior of the blood vessel.

Systems and Methods for determining a position of an object introduced into a body. An RF pilot tone is generated and is radiated into the body. Response signals modulated by the radiating into the body are received by a plurality of MRI receiver coils arranged spatially distributed outside the body and are converted into respective measurement signals. From the measurement signals, the position of the object is determined.

A configurable coil arrangement for use with MRI-guided procedures is provided that facilitates optimal imaging for both pre-procedure planning and imaging of the target sites during the procedure. The coil arrangement includes a plurality of connected coil elements. Spacers connecting the coil elements can be adjustable and/or deformable to provide one or more openings in the coil arrangement of optimal size for accessing the subject within the imaged region. Individual coil elements can also be removed to provide access openings during such procedures, or left in the array for improved pre- and post-procedure image quality. The MRI system can be configured to detect configurations of the coil arrangement and modify imaging parameters to optimize image quality.

Provided is a method and system for delivering a diagnostic agent to a site in the brain of a subject for imaging at least a portion of the brain site on a medical imaging system. The method and system includes a catheter device with associated lumens having diagnostic agent ports for delivering the diagnostic agent (e.g., infusate) through the lumens and advancing the diagnostic agent so as to exit out from the lumens to at least a portion of the brain site and while sealing a portion of the brain site thereby preventing the exited diagnostic agent from travelling proximally beyond the sealing location, and at the same time imaging at least a portion of the brain site during at least a portion of the sealing duration so that the brain site can be visualized on a medical imaging system. The diagnostic agent (infusate) is able to highlight borders and internal patterns of the deep structures of the brain thereby enabling direct targeting. Ultimately this leads to reduced complications, enhanced therapy, and the elimination of the need for awake surgery. The method and system provides the capability heretofore not possible to visualize the small, often indistinct regions, which will greatly improve clinical outcomes with therapeutic interventions.