A T1-weighted turbo-spin-echo magnetic resonance imaging system configured to capture data associated with a subject's heart during a time period and produce MR images has a dark-blood preparation module, a data capture module, and an image reconstruction module. The dark-blood preparation module performs dark-blood preparation through double inversion during some, but not all of the heartbeats within the time period. The data capture module configured performs data readouts to capture imaging data of an imaging slice during every heartbeat in which dark-blood preparation is performed. The data capture module also performs a steady state maintenance step during every heartbeat in which dark-blood preparation is not performed in order to maintain maximum T1-weighting. The image reconstruction module configured to reconstruct a T1-weighted image based on the imaging data.

An ear-worn device includes a speaker, an optical emitter, an optical detector, a processor, and a housing configured to be positioned within an ear of a subject, wherein the housing encloses the speaker, optical emitter, optical detector, and processor. The housing includes at least one window that exposes the optical emitter and optical detector to the ear of the subject, and the housing includes at least one aperture through which sound from the speaker can pass. Light transmissive material is located between the optical emitter and the at least one window and is configured to deliver light emitted from the optical emitter to an ear region of the subject at one or more predetermined locations. Light transmissive material is positioned between the optical detector and the at least one window and is configured to collect light external to the housing and deliver the collected light to the optical detector.

An MRI image processing and analysis system may identify instances of structure in MRI flow data, e.g., coherency, derive contours and/or clinical markers based on the identified structures. The system may be remotely located from one or more MRI acquisition systems, and perform: error detection and/or correction on MRI data sets (e.g., phase error correction, phase aliasing, signal unwrapping, and/or on other artifacts); segmentation; visualization of flow (e.g., velocity, arterial versus venous flow, shunts) superimposed on anatomical structure, quantification; verification; and/or generation of patient specific 4-D flow protocols. A protected health information (PHI) service is provided which de-identifies medical study data and allows medical providers to control PHI data, and uploads the de-identified data to an analytics service provider (ASP) system. A web application is provided which merges the PHI data with the de-identified data while keeping control of the PHI data with the medical provider.

In some embodiments, a wound monitoring and/or therapy apparatus includes a wound dressing configured to be positioned in contact with a wound, the wound dressing comprising one or more sensors configured to obtain measurement data of at least one of the wound or periwound. The apparatus can also include a controller configured to maintain a device clock indicative of a non-real time clock, receive measurement data obtained by the one or more sensors, and transmit measurement data to a remote computing device according to a security protocol, the security protocol comprising including the device clock associated with the measurement data in the transmission.

A measurement system is provided with an array of laser diodes with one or more Bragg reflectors. At least a portion of the light generated by the array is configured to penetrate tissue comprising skin. A detection system configured to: measure a phase shift, and a time-of-flight, of at least a portion of the light from the array of laser diodes reflected from the tissue relative to the portion of the light generated by the array; generate one or more images of the tissue; detect oxy- or deoxy-hemoglobin in the tissue; non-invasively measure blood in blood vessels within or below a dermis layer within the skin; measure one or more physiological parameters based at least in part on the non-invasively measured blood; and measure a variation in the blood or physiological parameter over a period of time.

A viewing navigation grid and imaging display especially useful for viewing recorded skin images.

Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.

Provided is a non-invasive system and method of determining pennation angle and/or fascicle length based on image processing. An ultrasound scan image is processed to facilitate distinguishing of muscle fiber and tendon. The processed ultrasound scan image is then analyzed. The pennation angle and/or fascicle length is determined based on the analysis. An example method includes receiving an ultrasound scan image of at least a portion of a skin layer as disposed above one or more additional tissue layers, the image provided by a plurality of pixels. The method continues by introducing noise into the pixels of the image and thresholding the pixels of the image to provide a binary image having a plurality of structural elements of different sizes. The method continues with morphing the structural elements of the binary image to remove small structural elements and connect large structural elements. With this resulting image, the method distinguishes muscle fiber and tendon from remaining elements and determines the pennation angle and/or the fascicle length from the muscle fiber and the tendon. Associated apparatuses and computer program products are also disclosed.

An arrangement is provided for monitoring the plantar temperature of the foot having a platform with at least two multi-layer temperature sensitive pads that measure the temperature of a sole of a user's feet. The platform has a scanner for scanning the bottom of the user's feet that produces a digital image thereof. A printed circuit board supports remote connectivity to a mobile application that transmits the scanned digital image of the users' feet to the mobile application for storage and delivery to a physician. The arrangement includes the mobile application that provides a series of diagnostic questions and prompts to the user and is configured to transmit data including the scanned images of the user's feet to a physician.

An imaging photoplethysmography (iPPG) system is provided. The iPPG system receives a sequence of images of different regions of the skin of the person, where each region including pixels of different intensities indicative of variation of coloration of the skin. The iPPG system further transforms the sequence of images into a multidimensional time-series signal, each dimension corresponding to a different region from the different regions of the skin. The iPPG system further processes the multidimensional time-series signal with a time-series U-Net neural network wherein the pass-through layers include a recurrent neural network (RNN) to generate a PPG waveform, where the vital sign of the person is estimated based on the PPG waveform, and the iPPG system further renders the estimated vital sign of the person.