Methods of the disclosure may include obtaining a first set of medical images at a first time point and a second set of medical images at a second time point, each set including at least two medical images. First and second algorithms may be used to calculate, respectively, first and third brain volume (BV) values at the first time point based on two or more images from the first set of medical images and second and fourth BV values at the second time point based on two or more images from the second set of medical images. A mathematical weight may be applied to at least one of the first, second, third, or fourth BV values. The first and third BV values may be averaged, and the second and fourth BV values may be averaged to determine overall BV values at the first and second time points, respectively.

System for performing fully automatic brain tumor and tumor-aware cortex reconstructions upon receiving multi-modal MRI data (T1, T1c, T2, T2-Flair). The system outputs imaging which delineates distinctions between tumors (including tumor edema, and tumor active core), from white matter and gray matter surfaces. In cases where existing MRI model data is insufficient then the model is trained on-the-fly for tumor segmentation and classification. A tumor-aware cortex segmentation that is adaptive to the presence of the tumor is performed using labels, from which the system reconstructs and visualizes both tumor and cortical surfaces for diagnostic and surgical guidance. The technology has been validated using a publicly-available challenge dataset.

A system for outputting a representation of a wound in tissue comprises a housing configured to removably receive at least a portion of a wireless communication device. At least one light source coupled to the housing is configured to emit excitation light to illuminate a target which includes at least a portion of the wound. A power supply contained in the housing is configured to provide power to the light source. A non-transitory computer-readable medium stores a program executable to cause the performance of operations comprising detecting signals responsive to illumination of the target, outputting the representation of the target based thereon, storing data relative to one or more target surface parameter based on the detected signals, and displaying the representation. The signals correspond to at least one of endogenous or exogeneous fluorescence, absorbance, and reflectance from at least one biological component in and/or on the target.

Methods and apparatus for predicting performance of an individual on a task, the method comprises receiving brain imaging data for the individual, wherein the brain imaging data comprises structural brain data, determining values for at least one characteristic of the structural brain data within regions of interest defined for a population of individuals having different performance levels, and predicting based on the determined values, a performance potential of the individual.

A method for quantitatively estimating heat transfer energy parameters in an encephalon through discretization and numerical calculation comprises the steps of: acquiring composition data regarding a distribution of matter in the encephalon; acquiring cerebral temperature data regarding a temperature distribution in the encephalon; calculating a thermal conductivity distribution in the encephalon as a function of the composition data; calculating a distribution of conductive heat flows in the encephalon as a function of the cerebral temperature data and the thermal conductivity distribution using the “general heat conduction equation”.

A method and system to treat headaches in a patient by performing surgery via at least one nostril. Data from a computer tomography scan of at least one nasal cavity and one sinus cavity of the patient and a completed headache questionnaire are matched to at least one nasal/sinus surgery plan to operate on at least one of: a nasal septum, at least one sinus cavity and at least one turbinate of the patient. The surgery plan is executed by installing a topical local anesthetic and decongestant onto the at least one turbinate forming an anesthetized decongested nasal cavity; infusing an anesthetic into the anesthetized decongested nasal cavity of the patient; dilating the at least one sinus ostium; incising at least one of: a first mucosal flap or a second mucosal flap of the nasal septum of the anesthetized decongested nasal cavity to expose deviated septal cartilage and bone; removing deviated cartilage and/or bone of the nasal septum; fracturing the at least one turbinate laterally away from the nasal septum; inspecting between the first mucosal flap and the second mucosal flap for a residual broken bone, a residual segment of cartilage or combinations thereof, surgically closing the first mucosal flap and the second mucosal flap of the nasal septum; and suctioning unwanted matter from the anesthetized decongested nasal cavity. An interactive system guides the surgery and provides a record thereof.

The present invention relates to a digital content-based method for providing therapeutics information, the method comprising: a first step of performing stimulation on a brain of a user to obtain fNIRS (functional near-infrared spectroscopy) data of the user; a second step of extracting a first brain activation area from a plurality of brain areas of the user using the obtained fNIRS data; a third step of determining a first brain state of the user, based on the first brain activation area; a fourth step of providing the user with a content determined corresponding to the first brain state determined in the third step under an XR (Extended Reality) environment; a fifth step in which the user performs a mission corresponding to the content; a sixth step of extracting a second brain activation area from the plurality of brain areas with reference to the fNIRS data of the user following performing the mission; and a seventh step of determining a second brain state of the user, based on the second brain activation area; an eighth step of determining information related to amelioration of the brain state of the user.

Various methods and systems are provided for a flexible, lightweight and low-cost stretchable radio frequency (RF) coil of a magnetic resonance imaging (MRI) system. In one example, a RF coil assembly for a MRI system includes a loop portion comprising distributed capacitance conductor wires, a coupling electronics portion including a pre-amplifier; and a stretchable material to which the loop portion and coupling electronics portion are attached and/or enclosed therein.

The source light having a range of optical wavelengths is split into sample light and reference light. The sample light is delivered into a sample, such that the sample light is scattered by the sample, resulting in signal light that exits the sample. The signal light and the reference light are combined into an interference light pattern having optical modes having oscillation frequency components respectively corresponding to optical pathlengths extending through the sample. Different sets of the optical modes of the interference light pattern are respectively detected, and high-bandwidth analog signals representative of the optical modes of the interference light pattern are output. The high-bandwidth analog signals are parallel processed, and mid-bandwidth digital signals are output. The mid-bandwidth digital signals are processed over an i number of iterations, and a plurality of low-bandwidth digital signals are output on the ith iteration. The sample is analyzed based on the low-bandwidth digital signals.

Approaches for performing magnetic resonance (MR) imaging of an anatomic region in conjunction with an ultrasound operation on the anatomic region include transmitting multiple ultrasound waves or pulses having a fundamental frequency and multiple harmonics to the anatomic region; transmitting an MR pulse sequence to the anatomic region and receiving, therefrom, MR signals within a band of frequencies; and causing the band of frequencies to be located between two adjacent frequencies of the harmonics.