The present invention proposes a radiation detector including a housing, a radiation detection panel accommodated in the housing and converting radiation incident from the outside of the housing into an electric signal, a printed circuit board electrically connected to the radiation detection panel and an intermediate plate that is disposed between the radiation detection panel and the printed circuit board, supports the radiation detection panel, and is electrically connected to the ground line of the printed circuit board, wherein the intermediate plate is transmissive to the radiation.

A method of forming a probability map is disclosed. According to one embodiment, a method may include: (1) obtaining multiple measures of multiple imaging parameters for every stop of a moving window on an image, wherein two neighboring ones of the stops of the moving window are partially overlapped with each other; (2) obtaining first probabilities of an event for the stops of the moving window by matching the measures of the imaging parameters to a classifier; and (3) obtaining second probabilities of the event for multiple voxels of a probability map based on information associated with the first probabilities.

A breast diffusion optical tomography (DOT) device includes a light source, a detector, a mechanical driver and a contour acquisitor without using optical fiber and reduce the system complexity. The light source includes M1 number of multi-wavelength near-infrared light emitters for a continuous-wave mode and M2 number of laser diodes of different wavelengths for a frequency-domain mode. The detector includes N1 number of silicon photomultipliers for detecting near-infrared light in the continuous-wave mode and N2 number of silicon photomultipliers for detecting near-infrared light in the frequency-domain mode. The mechanical driver adjusts a distance between the light source and the detector. The contour acquisitor obtains the geometry of a patient's breast for reconstruction. The DOT device uses amplitude and phase information obtained in the frequency-domain mode to estimate initial optical parameters of tissues and then apply for reconstruction in the continuous-wave mode.

What is disclosed is a system and method for automatically segmenting a breast from surrounding tissue in a thermal image. A thermal image of at least one breast of the patient is received. The thermal image is then analyzed to identify a set of N points around the breast, a contour of an outline of the body, and isotherms of the axilla and infra-mammary fold. Thereafter, the points are connected together to form a N-sided irregular polygon which segments the breast from surrounding tissue. Each of the points is a vertex of the polygon and comprises a draggable object which enables a user to selectively manipulate a shape of the polygon. A user can add/delete vertices from the polygon as desired. The area of the image encompassed by the polygon is communicated to a breast cancer screening algorithm performing automated or semi-automated screening.

What is disclosed is an apparatus for enabling privacy for patients undergoing breast cancer screening in a non-clinical setting. One embodiment of the present apparatus comprises an enclosure in which a person can remove one or more garments to expose their breasts to a thermal camera for breast cancer screening. The enclosure is such that at least the breast area of that person is shielded from view by third parties. The apparatus also comprises a thermal camera for capturing thermal images of the exposed breast area. The thermal camera is connected to a robotic arm that changes the camera angle relative to real-world coordinates so that thermal images can be taken of the breast area from any angle between a frontal view and a left/right lateral view. A processor which executes a software interface tool for semi-automated or automated breast cancer screening based on the thermal images of the breast.

The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid or derivative thereof. The disclosure further describes methods and compositions for incorporating the compounds as used for the targeted imaging of non-small cell lung cancer (NSCLC) in human subjects. Conjugation of the amino acid linking groups increase specificity and detection of the compound. Methods and compositions for use thereof in diagnostic imaging are contemplated.

Embodiments of the invention include a breast nipple areola complex tattoo stencil comprising first, second and third stencil sections. The first stencil section defines an areola area. The second stencil section defines a nipple area and tubercle areas. One or more registration elements on the first and/or second stencil sections enable registration of the second stencil section to the first stencil section. The third stencil section defines one or both of a nipple shading area and a nipple highlight area. One or more registration elements on the third and/or second stencil sections enable registration of the third stencil section to the second stencil section.

A breast imaging apparatus includes a radiation source that irradiates a breast of a subject with radiation, a radiation detector that detects the radiation transmitted through the breast to output a radiographic image, and an ultraviolet light source that performs irradiation of ultraviolet light. The ultraviolet light source irradiates an imaging table, a face guard, a pressing plate, and the like with the ultraviolet light in a case where a turn-on command signal input from an operator through an input device is input.

A method for characterising a mechanical property of a material. The method comprises the steps of providing the material having a deformable portion and providing a device having an optical element that is arranged to detect electromagnetic radiation.

A diffuse optical spectroscopic imaging (DOSI) apparatus for tissue spectroscopy measures absorption and scattering properties of tissue using multi-frequency frequency domain photon migration in a modular or networkable platform to provide full broadband information content. The apparatus includes: a broadband signal generator; a driver having an input coupled to the signal generator; a light source coupled to the driver, the light source for exposing the tissue to broadband modulated light at a plurality of wavelengths; an optical detector for receiving returned light from the tissue; an amplitude detection circuit communicated to the optical detector; a phase detection circuit communicated to the optical detector; and a plurality of filters and amplifiers, wherein the optical detector, amplitude detection circuit and phase detection circuit are interconnected with each other by corresponding ones of the plurality of filters and amplifiers to isolate signals and increase signal-to-noise ratio.