A wearable physiological signal detecting device includes a device main body and a telescopic structure. The device main body has a strap which surrounds to form a wearable space. The telescopic structure is disposed in the strap and has first surfaces and second surfaces. Each of the first surfaces faces the corresponding second surface. Each of the first surfaces and the corresponding second surface continuously move close and contact each other to assume a first state. The strap can be forced so that each of the first surfaces and the corresponding second surface move away from each other and have an angle to assume a second state. The size of the wearable space when the first surface and the corresponding second surface assume the second state is greater than the size of the wearable space when the first surface and the corresponding second surface assume the first state.

The present application discloses a pulse simulator. The pulse simulator includes a pulse simulation assembly configured to receive a pulse simulation signal and simulate a pulse of a living body based on the pulse simulation signal. The pulse simulation assembly includes a mounting plate; a plurality of retractable bolts on the mounting plate; and a plurality of drivers coupled to the plurality of retractable bolts. Each of the plurality of retractable bolts has a first end attached to the mounting plate and a second end opposite to the first end. Each of the plurality of drivers is configured to drive one of the plurality of retractable bolts to retract and extend between a first position and a second position thereby adjusting a distance between a simulated skin portion and the mounting plate in a region corresponding to the one of the plurality of retractable bolts.

Provided herein are methods for in-vivo assessment of intraventricular flow shear stress, risk of hemolysis, also the location and extent of blood flow stasis regions and inside a cardiac chamber or blood vessel. Also provided herein are systems for performing such methods. Also provided herein are methods for assessing hemolysis and/or thrombosis risk in patients implanted with an LVAD. LVAD positioning and/or speed may be adjusted based on the results obtained by using methods described herein, and the risk for hemolysis and/or thrombosis can be minimized.

An electronic device includes a wearing portion to be worn by a subject and a sensor unit that includes a sensor configured to detect a pulse wave of the subject. The sensor unit includes a displacement portion configured to contact a measured part of the subject and to be displaced in accordance with the pulse wave of the subject when the wearing portion is worn by the subject.

A blood and cardiovascular condition determination apparatus is provided. The blood and cardiovascular condition determination apparatus may include a first pulse wave signal sensor, a second pulse wave signal and a processing unit. The first pulse wave signal sensor may be configured to generate a first pulse wave signal associated with a first section of a living body. The second pulse wave signal sensor may be configured to generate a second pulse wave signal associated with a second section of the living body. The processing unit may determine at least one blood and cardiovascular condition based on the first pulse wave signal and the second pulse wave signal. The at least one blood and cardiovascular condition may include at least one of a blood pressure, a blood sugar level, a blood oxygen level, a blood vessel aging level, or a blood viscosity.

A device and a method for rapid detection of blood viscosity based on an ultrasonic guided wave of a micro-fine metal tube are provided. The device comprises a blood sampling unit and a blood sampling electrical circuit that are electrically connected with each other and a device shell; the sample feeding tube and the sample discharging tube are respectively arranged at two sides of the device shell, the inlet of the sampling tube is communicated with the outside of the device shell, the outlet of the sampling tube is communicated with the inlet of the blood micro-flow pump through the micro-fine metal tube, the outlet of the blood micro-flow pump is communicated with the inlet of the sample discharging tube, and the outlet of the sample discharging tube is communicated with the outside of the device shell; the magnetostrictive component is arranged outside the micro-fine metal tube.

Using whole blood viscosity (WBV) data collected at various shear rates in conjunction with other clinically relevant informationsuch as age, gender, and other medical history informationone can generate information indicative of a current or physiological condition of a subject. Such generation can be accomplished using machine learning, such as a trained algorithm. One can also train an algorithm using WBV and other clinically relevant information. The described approaches allow for early detection and treatment of conditions, such as sepsis, as well as the evaluation of a treatment or treatments administered to a patient in need.

A system and method are described for controlling a vehicle interior environmental condition. A biometric sensor senses a biometric condition of a vehicle seat occupant and generates a sensed biometric condition value. A controller receives the sensed biometric condition value, a sensed interior environmental condition value, and a sensed exterior environmental condition value. Each of multiple exterior environmental condition values has an associated biometric condition value defined as optimal for the vehicle occupant. The controller determines the optimal biometric condition value associated with the sensed exterior environmental condition value, compares the optimal biometric condition value to the sensed biometric condition value, and in response to a difference between the optimal biometric condition value and the sensed biometric condition value, generates a control signal to control an actuator to control the controllable interior environmental condition to reduce the difference between sensed biometric condition value and the optimal biometric condition value.

Systems, methods and computer-readable media are provided for monitoring patients and quantitatively predicting whether an event such as a significant change in health status meriting intervention, is likely to occur within a future time interval subsequent to computing the prediction. Medical data for a patient is collected from one or more different inputs and used to determine time series data. From this, a forecasted numerical value is computed for one or more physiologic parameters associated with the patient, which may be used to further monitor the patient and facilitate decision making about a need for intensified monitoring or intervention to prevent or manage deterioration of hemostasis. An evolutionary algorithm, such as particle swarm optimization and/or differential evolution, may be used to determine the most probable value of the physiologic parameter(s) at one or more future times.

The invention relates to a system for challenging the pericardial space, to provide an indication of the risk of cardiac tamponade in a patient, as well as methods for diagnosis of, and determination of the extent of, a tamponade, and treating a patient in whom there is a detected cardiac tamponade.