A biosensor including light emitting elements and a light receiving element disposed on a principal surface of a wiring board; a light shielding portion disposed between a light-emitting-element sealing portion and a light-receiving-element sealing portion; a base medium having light transmitting properties, disposed in parallel with the wiring board with the light shielding portion therebetween; an adhesion layer having light transmitting properties that bonds the base medium with the light-emitting-element sealing portion, the light-receiving-element sealing portion, and the light shielding portion; and a first electrocardiograph electrode attached to a principal surface of the base medium. Both end portions of the adhesion layer and both end portions of the base medium are disposed such that they overlap neither of the light-receiving-element sealing portion nor the light-emitting-element sealing portion when viewed from a direction normal to the principal surface of the wiring board.

A biosensor including light emitting elements and a light receiving element disposed on a principal surface of a wiring board; a light shielding portion disposed between a light-emitting-element sealing portion and a light-receiving-element sealing portion; a base medium having light transmitting properties, disposed in parallel with the wiring board with the light shielding portion therebetween; an adhesion layer having light transmitting properties that bonds the base medium with the light-emitting-element sealing portion, the light-receiving-element sealing portion, and the light shielding portion; and a first electrocardiograph electrode attached to a principal surface of the base medium. Both end portions of the adhesion layer and both end portions of the base medium are disposed such that they overlap neither of the light-receiving-element sealing portion nor the light-emitting-element sealing portion when viewed from a direction normal to the principal surface of the wiring board.

The invention relates to the system and method of remote ECG monitoring, remote disease screening, and early-warning system based on wavelet analysis. The system includes a wireless ECG signal acquisition device, a mobile terminal, and a cloud storage platform. The wireless ECG signal acquisition device worn on the user's chest is used to collect ECG signals anywhere and anytime. The method includes transmitting the ECG signals to the mobile terminal using the wavelet analysis algorithm, analyzing and processing the received ECG signal, and uploading the processed ECG signals to the cloud storage platform. The cloud storage platform stores users' personal information and ECG signals. According to the ECG features detection with support vector machine learning algorithm for heart diseases diagnosis and features classification, the system gives feedback report and proposal, and transmits them to the mobile terminal.

The invention relates to the system and method of remote ECG monitoring, remote disease screening, and early-warning system based on wavelet analysis. The system includes a wireless ECG signal acquisition device, a mobile terminal, and a cloud storage platform. The wireless ECG signal acquisition device worn on the user's chest is used to collect ECG signals anywhere and anytime. The method includes transmitting the ECG signals to the mobile terminal using the wavelet analysis algorithm, analyzing and processing the received ECG signal, and uploading the processed ECG signals to the cloud storage platform. The cloud storage platform stores users' personal information and ECG signals. According to the ECG features detection with support vector machine learning algorithm for heart diseases diagnosis and features classification, the system gives feedback report and proposal, and transmits them to the mobile terminal.

A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

A catheter may include electrodes for transvascular nerve stimulation. The electrodes may be positioned within lumens of the catheter and aligned with apertures in the outer wall of the catheter. The electrodes may produce focused electrical fields for stimulation of one or more nerves. In one embodiment, the catheter may include a set of proximal electrodes and a set of distal electrodes, and the proximal electrodes may stimulate a patient's left phrenic nerve and the distal electrodes may stimulate a patient's right phrenic nerve.

Systems and methods for assessing sympathetic nervous system (SNS) tone for renal neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a detector attached to or implanted in a patient and a receiver communicatively coupled to the detector. The detector can measure cardiac data and the receiver and/or a device communicatively coupled thereto can analyze the cardiac data to provide one or more SNS tone indicators. The SNS tone indicators can be used to determine whether a patient will be responsive to a neuromodulation therapy and/or whether a neuromodulation therapy was effective.

Systems and methods for assessing sympathetic nervous system (SNS) tone for renal neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a detector attached to or implanted in a patient and a receiver communicatively coupled to the detector. The detector can measure cardiac data and the receiver and/or a device communicatively coupled thereto can analyze the cardiac data to provide one or more SNS tone indicators. The SNS tone indicators can be used to determine whether a patient will be responsive to a neuromodulation therapy and/or whether a neuromodulation therapy was effective.

Provided are systems for measuring an electrocardiogram (ECG) using a wearable device. An example system includes the wearable device. The wearable device has a means for recording an electrical signal from a single wrist of a patient. The wearable device also has a means for detecting a pulse of the patient and recording a photoplethysmogram (PPG) signal, via a PPG optical sensor associated with the wearable device. The wearable device further has a means for generating the electrical signal segments being time-locked to the PPG signal by utilizing the PPG signal as a reference signal. Furthermore, the wearable device has a means for summing the electrical signal segments in a given time period and dividing by the number of segments to produce an average ECG waveform.

Provided are systems for measuring an electrocardiogram (ECG) using a wearable device. An example system includes the wearable device. The wearable device has a means for recording an electrical signal from a single wrist of a patient. The wearable device also has a means for detecting a pulse of the patient and recording a photoplethysmogram (PPG) signal, via a PPG optical sensor associated with the wearable device. The wearable device further has a means for generating the electrical signal segments being time-locked to the PPG signal by utilizing the PPG signal as a reference signal. Furthermore, the wearable device has a means for summing the electrical signal segments in a given time period and dividing by the number of segments to produce an average ECG waveform.