Offset illumination using multiple emitters in a fluorescence imaging system is described. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The emitter comprises a first emitter and a second emitter for emitting different wavelengths of electromagnetic radiation. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises a laser mapping pattern.

An arrangement structure for a biological sensor includes a biological sensor of a non-contact type provided in a seat on which a human is seated. The biological sensor detecting biological information of the human with electromagnetic waves. The biological sensor is arranged at a position in the seat avoiding a member that constitutes the seat and interferes with passage of the electromagnetic waves.

A sensor system has a low-noise sensor controller providing communications between an active-temperature-regulated optical sensor and an external monitor. A low-noise sensor controller drives optical emitters, receives resulting detected signals after attenuation by a blood perfused tissue site and communicates the detector signals to the attached signal processor. An optically-isolated controller front-end receives and digitizes the detected signals. A controller serializer transmits the digitized detector signal to the processor via a single, shielded coaxial cable.

A computer-implemented method for generating an annotated photoplethysmography signal, includes: recording an electrocardiogram or ECG signal; recording a photoplethysmography or PPG signal, semi-synchronously with the recording of the ECG signal; annotating segments in the ECG signal either algorithm-based or expert-based; time-aligning the PPG signal and the ECG signal; detecting ECG beats in the ECG signal; detecting PPG beats in the PPG signal; pairing the ECG beats onto the PPG beats; deriving annotations for PPG signal segments based on the nature of the ECG segment annotations and on how the ECG beats can be paired with the PPG beats; and annotating the PPG signal segments using the annotations, thereby generating the annotated PPG signal.

A live subject tissue detection device includes a light source configured to emit light onto the tissue of a subject, a photodetector configured to receive light reflected from the tissue and light reflected from the blood flow, wherein the light reflected from the blood flow has a Doppler shift relative to the light reflected from the tissue, and generate a high frequency Doppler signal based on the Doppler shift, a detection circuitry configured to receive the high frequency Doppler signal from the photodetector and convert the high frequency Doppler signal into a low frequency signal, and at least one processor configured to compute parameters of the low frequency signal, compare the parameters of the low frequency signal to respective reference values, and determine a presence of live tissue based on the comparison.

Provided is a biosignal measuring device 100 capable of easily calculating data on blood flow volume, blood flow velocity, and path length in the subject P as data for the time domain, and simplifying brain disease diagnosis based on this. It relates to a biosignal imaging device 1 and a brain image-based brain disease diagnosis system. To this end, the biosignal measuring apparatus 100 detects the reflected light signal after the light irradiated from the plurality of light irradiation units 111 and the plurality of light irradiation units 111 for irradiating light to the subject P are reflected. Based on the light signal detected by the measurement unit 110 including a plurality of light receiving units 112 and the light irradiation control unit 121 for controlling the light signal irradiated from each light irradiation unit 111 and the light receiving unit 112 and a calculation unit 120 including a signal processing unit 122 that calculates data for the subject P in the time domain.

Systems and methods are provided for detecting the flow of blood or other fluids in biological tissue by illuminating the biological tissue with two or more beams of coherent light and detecting responsively emitted light. A difference in wavelength, coherence length, beam divergence, or some other property of the beams of illumination causes the beams to preferentially scatter from, be absorbed by, or otherwise interact with respective elements of the biological tissue. Flow properties in one or more regions of the biological tissue (e.g., a region with which both beams of light preferentially interact, a region with which only one of the beams preferentially interacts) could be determined based on detected responsively emitted light from the biological tissue. Variations in speckle patterns over time and/or space, Doppler shifts, or some other properties of the detected light could be used to determine the flow properties.

The present invention relates to a device for determining information relating to a suspected occluding structure. It is described to provide (210) a spectral resolving unit with at least one broadband radiation. The at least one broadband radiation comprises a first broadband radiation acquired from a region of interest within a vascular structure. An occluding structure is suspected to be located within the region of interest and wherein the first broadband radiation is associated with the suspected occluding structure. At least one spectrally resolved data set is determined (220) on the basis of the at least one broadband radiation, wherein the at least one spectrally resolved data set comprises a first spectrally resolved data set determined on the basis of the first broadband radiation. A processing unit is provided (230) with the at least one spectrally resolved data set on the basis of the at least one broadband radiation. The processing unit determines (240) information relating to the suspected occluding structure, comprising utilisation of the first spectrally resolved data set.

An optical physiological sensor configured to be secured to a user's nose includes a first prong configured to be positioned proximate an outside portion of the nose, a second prong configured to be positioned proximate an inside portion of the user's nose, a winged portion coupled to the first prong and configured to contact tissue of the user, one or more emitters configured to emit light of one or more wavelengths into the tissue, and one or more detectors configured to detect at least a portion of the light emitted from the one or more emitters after attenuation through at least a portion of the tissue. In some configurations, the winged portion comprises a width that is greater than a width of the second prong. In some configurations, at least a portion of the winged portion is curved toward the second prong.

An electronic device according to one embodiment of the present disclosure may include: a housing; an optical element unit which may be configured to emit light toward a user's body, receive light reflected from the user's body, and convert the received light into a first signal; an IC element which may be configured to convert the first signal provided from the optical element unit into a second signal, and provide the second signal to a main circuit board disposed in the housing; a first circuit board that may be disposed between the optical element unit and the IC element and may be electrically connected to the optical element unit and the IC element; and a second circuit board that may include at least one first opening in which the IC element is mounted. The housing may include at least one transparent region such that the light generated by the optical element unit is transmitted through the transparent region to an exterior of the housing.