A device for monitoring a health parameter of a person is disclosed. The device includes a device body, a radio frequency (RF) front-end connected to the device body and including a semiconductor substrate and an antenna array including at least one transmit antenna configured to transmit radio waves below the skin surface of a person and a two-dimensional array of receive antennas configured to receive radio waves, the received radio waves including a reflected portion of the transmitted radio waves, wherein the semiconductor substrate includes circuits configured to generate signals in response to the received radio waves, and an alignment feature integrated into the device body and configured to align the antenna array with an object.

Disclosed herein are in vivo non-invasive methods and devices for the measurement of the hemodynamic parameters and aortic valve conformance and compliance in a subject. The method requires measuring the peripheral pulse volume waveform (PVW), the peripheral pulse pressure waveform (PPW), and the peripheral pulse velocity waveform (PUW) from the same artery using a non-invasive device. The waveforms PPW and PUW are used to calculate the waveform dPdU which is used to determine aortic valve ejection volume, closure volume, and quality factor, as well as stroke volume and cardiac output. The disclosed methods and devices are useful in the diagnosis and treatment of aortic valve disease, disorders, and dysfunction.

Disclosed herein are in vivo non-invasive methods and devices for the measurement of the hemodynamic parameters and aortic valve conformance and compliance in a subject. The method requires measuring the peripheral pulse volume waveform (PVW), the peripheral pulse pressure waveform (PPW), and the peripheral pulse velocity waveform (PUW) from the same artery using a non-invasive device. The waveforms PPW and PUW are used to calculate the waveform dPdU which is used to determine aortic valve ejection volume, closure volume, and quality factor, as well as stroke volume and cardiac output. The disclosed methods and devices are useful in the diagnosis and treatment of aortic valve disease, disorders, and dysfunction.

A hemodynamic parameter (Hdp) monitoring system for diagnosing a health condition of a patient and for establishing Hdp marker values or Hdp surrogate marker values for purposes of comparison with Hdp values of a patient is provided. An Hdp monitor senses, measures, and records Hdp values exhibited by the patient during a basal or non-exposure period and furthermore Hdp values exhibited by the patient during or after an exposure period during which the patient is exposed to low-energy electromagnetic output signals. An electrically-powered generator is adapted to be actuated to generate said low-energy electromagnetic carrier output signals for exposing or applying to the patient such output signals during said exposure period.

A hemodynamic parameter (Hdp) monitoring system for diagnosing a health condition of a patient and for establishing Hdp marker values or Hdp surrogate marker values for purposes of comparison with Hdp values of a patient is provided. An Hdp monitor senses, measures, and records Hdp values exhibited by the patient during a basal or non-exposure period and furthermore Hdp values exhibited by the patient during or after an exposure period during which the patient is exposed to low-energy electromagnetic output signals. An electrically-powered generator is adapted to be actuated to generate said low-energy electromagnetic carrier output signals for exposing or applying to the patient such output signals during said exposure period.

Apparatus and methods are provided for performing a medical procedure using a stapler apparatus including a reusable handle portion including a shaft include proximal and distal ends, a disposable end effector attached to the distal end of the shaft of the reusable handle carrying one or more staples. For example, the end effector may include first and second jaws movable relative to one another between open and closed positions, the first jaw carrying a cartridge which includes the one or more staples. A Doppler sensor, cutting element, thermal element, and/or grasper may be provided on the end effector. The end effector is introduced into a patient's body, tissue is positioned/locked between the jaws, and a plurality of staples are deployed into the tissue. The Doppler sensor is used to confirm that blood flow has discontinued in the stapled tissue, and the cutting element is actuated to sever the stapled tissue.

The invention provides a magnetic inductive sensing system for sensing electromagnetic signals emitted from a body in response to electromagnetic excitation signals applied to the body. The electromagnetic signals are generated and sensed by the same loop resonator which comprises a single-turn loop antenna and a tuning capacitor. The loop antenna of the resonator and a signal generation means for exciting the resonator to generate excitation signals are together configured so as to optimize the value of a ratio between the radial frequency of the generated electromagnetic excitation signals and a reference frequency of the antenna, where the reference frequency is the frequency for which one wavelength of the generated excitation signals (waves) matches the circumferential length of the antenna. This ratio, which corresponds to a normalized radial frequency of the generated excitation signals, is maintained between a value of 0.025 and 0.50.

The invention provides a magnetic inductive sensing system for sensing electromagnetic signals emitted from a body in response to electromagnetic excitation signals applied to the body. The electromagnetic signals are generated and sensed by the same loop resonator which comprises a single-turn loop antenna and a tuning capacitor. The loop antenna of the resonator and a signal generation means for exciting the resonator to generate excitation signals are together configured so as to optimize the value of a ratio between the radial frequency of the generated electromagnetic excitation signals and a reference frequency of the antenna, where the reference frequency is the frequency for which one wavelength of the generated excitation signals (waves) matches the circumferential length of the antenna. This ratio, which corresponds to a normalized radial frequency of the generated excitation signals, is maintained between a value of 0.025 and 0.50.

A method includes determining a heart beat signal during acquisition of MR images obtained at a plurality of cardiac cycles; determining at least one physiological parameter of a heart obtained at the plurality of cardiac cycles; determining a model including, determining, in each of the cardiac cycles, a variable time interval of variable duration and at least one additional time interval based on the heart beat signal and the at least one physiological parameter, the at least one additional time interval having a lower variability in duration than the variable time interval; determining a duration of the variable time interval and a duration of the cardiac cycle for each of the cardiac cycles based on the heart beat signal and the at least one physiological parameter; and assigning the MR images to the different cardiac phases based on the variable time interval and each of the cardiac cycles.

A method includes determining a heart beat signal during acquisition of MR images obtained at a plurality of cardiac cycles; determining at least one physiological parameter of a heart obtained at the plurality of cardiac cycles; determining a model including, determining, in each of the cardiac cycles, a variable time interval of variable duration and at least one additional time interval based on the heart beat signal and the at least one physiological parameter, the at least one additional time interval having a lower variability in duration than the variable time interval; determining a duration of the variable time interval and a duration of the cardiac cycle for each of the cardiac cycles based on the heart beat signal and the at least one physiological parameter; and assigning the MR images to the different cardiac phases based on the variable time interval and each of the cardiac cycles.