A vascular graft includes a flexible substrate that can assume an unrolled configuration, in which the substrate extends along a main extension plane, and a rolled-up configuration, in which a first side of the substrate is facing radially inward and a second sideof the substrate is facing radially outward. At least one pressure sensing device is arranged on the first side of the substrate and includes a first electrode, a second electrode, and a piezoelectric element arranged between the two electrodes. At least one velocity sensing device is arranged on the first side of the substrate and a first electrode, a second electrode, and a piezoelectric element arranged between the electrodes. The graft can be used in a vascular graft system.

A vascular graft includes a flexible substrate that can assume an unrolled configuration, in which the substrate extends along a main extension plane, and a rolled-up configuration, in which a first side of the substrate is facing radially inward and a second sideof the substrate is facing radially outward. At least one pressure sensing device is arranged on the first side of the substrate and includes a first electrode, a second electrode, and a piezoelectric element arranged between the two electrodes. At least one velocity sensing device is arranged on the first side of the substrate and a first electrode, a second electrode, and a piezoelectric element arranged between the electrodes. The graft can be used in a vascular graft system.

A removable smartphone case is disclosed. The removable smartphone case includes a case body configured to receive a smartphone, a radio frequency (RF) front-end connected to the case body and including a semiconductor substrate and an antenna array including at least one transmit antenna configured to transmit radio waves below the skin surface of a person and a two-dimensional array of receive antennas configured to receive radio waves, the received radio waves including a reflected portion of the transmitted radio waves, wherein the semiconductor substrate includes circuits configured to generate signals in response to the received radio waves, a communications interface connected to the case body and configured to transmit digital data that corresponds to the signals generated by the semiconductor substrate from the removable smartphone case, and an alignment feature integrated into the case body and configured to align the antenna array with an object.

Disclosed embodiments relate to apparatuses and methods for a skin perfusion pressure determination device. In some embodiments, a skin perfusion pressure determination device can include a sensor module including a first sensor for sensing a first parameter associated with a pressure exerted on a target area by the sensor module and a second sensor for sensing a second parameter associated with an amount of blood perfusion at the target area, wherein the first sensor and the second sensor are arranged such that, when the sensor module is pressed against the target area the first sensor produces an output corresponding to the sensed first parameter and the second sensor produces an output corresponding to the sensed second parameter, a proximal end assembly configured to contact the target area, a display to provide feedback of the pressure exerted on a target area and/or the amount of blood perfusion at the target area, and a communication device for providing data transfer from the skin perfusion pressure determination device to a control unit.

Disclosed embodiments relate to apparatuses and methods for a skin perfusion pressure determination device. In some embodiments, a skin perfusion pressure determination device can include a sensor module including a first sensor for sensing a first parameter associated with a pressure exerted on a target area by the sensor module and a second sensor for sensing a second parameter associated with an amount of blood perfusion at the target area, wherein the first sensor and the second sensor are arranged such that, when the sensor module is pressed against the target area the first sensor produces an output corresponding to the sensed first parameter and the second sensor produces an output corresponding to the sensed second parameter, a proximal end assembly configured to contact the target area, a display to provide feedback of the pressure exerted on a target area and/or the amount of blood perfusion at the target area, and a communication device for providing data transfer from the skin perfusion pressure determination device to a control unit.

A system for determining blood flow to and from the brain of a patient includes a plurality of magnetic elements configured to be positioned adjacent to the neck of the patient and apply at least one magnetic field to the neck of the patient. The system includes a plurality of electrodes configured to be in electrical contact with the neck of the patient, the electrodes configured to detect a voltage induced across the neck of the patient responsive to the applied magnetic field and blood flow through the neck of the patient. The system includes a support component for holding the plurality of magnetic elements and the plurality of electrodes at the neck of the patient.

A system for determining blood flow to and from the brain of a patient includes a plurality of magnetic elements configured to be positioned adjacent to the neck of the patient and apply at least one magnetic field to the neck of the patient. The system includes a plurality of electrodes configured to be in electrical contact with the neck of the patient, the electrodes configured to detect a voltage induced across the neck of the patient responsive to the applied magnetic field and blood flow through the neck of the patient. The system includes a support component for holding the plurality of magnetic elements and the plurality of electrodes at the neck of the patient.

An unattended approach can increase the reproducibility and safety of the treatment as the chance of over/under treating of a certain area is significantly decreased. On the other hand, unattended treatment of uneven or rugged areas can be challenging in terms of maintaining proper distance or contact with the treated tissue, mostly on areas which tend to differ from patient to patient (e.g. facial area). Delivering energy via a system of active elements embedded in a flexible pad adhesively attached to the skin offers a possible solution. The unattended approach may include delivering of multiple energies to enhance a visual appearance.

The invention relates to evaluation of maturity of arteriovenous (AV) fistula using guidewires that measure intravascular blood flow and/or pressure. The invention provides methods of evaluating AV fistula maturation using an instrumented guidewire to measure intravascular flow and/or pressure. By using a small diameter guidewire that does not interfere substantially with the flow, an accurate measurement can be made that is useful for identifying when a fistula is mature and therefore ready to be used for hemodialysis. The flow of blood through the fistula is measured using the guidewire and the measured flow and/or pressure of blood is used to determine if the fistula is mature.

The invention relates to evaluation of maturity of arteriovenous (AV) fistula using guidewires that measure intravascular blood flow and/or pressure. The invention provides methods of evaluating AV fistula maturation using an instrumented guidewire to measure intravascular flow and/or pressure. By using a small diameter guidewire that does not interfere substantially with the flow, an accurate measurement can be made that is useful for identifying when a fistula is mature and therefore ready to be used for hemodialysis. The flow of blood through the fistula is measured using the guidewire and the measured flow and/or pressure of blood is used to determine if the fistula is mature.