Described here are wireless monitoring devices, systems, and methods for estimating one or more physiological parameters of a patient. These devices and systems may measure or receive a signal waveform transmitted through one or more of fluid and a physiological structure of a patient. This measured signal waveform may be processed to generate waveform parameter data used to estimate a physiological parameter such as blood velocity, heart wall thickness, and the like.

A system for non-invasively determining an indication of an individual's blood pressure is described. In certain embodiments, the system calculates pulse wave transit time using two acoustic sensors. The system can include a first acoustic sensor configured to monitor heart sounds of the patient corresponding to ventricular systole and diastole and a second acoustic sensor configured to monitor arterial pulse sounds at an arterial location remote from the heart. The system can advantageously calculate a arterial pulse wave transit time (PWTT) that does not include the pre-ejection period time delay. In certain embodiments, the system further includes a processor that calculates the arterial PWTT obtained from the acoustic sensors. The system can use this arterial PWTT to determine whether to trigger an occlusive cuff measurement.

A system for non-invasively determining an indication of an individual's blood pressure is described. In certain embodiments, the system calculates pulse wave transit time using two acoustic sensors. The system can include a first acoustic sensor configured to monitor heart sounds of the patient corresponding to ventricular systole and diastole and a second acoustic sensor configured to monitor arterial pulse sounds at an arterial location remote from the heart. The system can advantageously calculate a arterial pulse wave transit time (PWTT) that does not include the pre-ejection period time delay. In certain embodiments, the system further includes a processor that calculates the arterial PWTT obtained from the acoustic sensors. The system can use this arterial PWTT to determine whether to trigger an occlusive cuff measurement.

Systems and methods for informing and evaluating neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a guidewire having a proximal portion, a distal portion configured to be positioned at a target site in a blood vessel of a human patient, and a sensing element positioned along the distal portion. The sensing element can be a pressure sensing element, a flow sensing element, an impedance sensing element, and/or a temperature sensing element. The system can further include a controller configured to obtain one or more measurements related to a physiological parameter of the patient via the sensing element. Based on the measurements, the controller can determine the physiological parameter and compare the parameter to a predetermined threshold. Based on the comparison, the controller and/or the operator can assess the likelihood of the patient benefiting from neuromodulation therapy.

Systems and methods for informing and evaluating neuromodulation therapy are disclosed herein. A system configured in accordance with embodiments of the present technology can include, for example, a guidewire having a proximal portion, a distal portion configured to be positioned at a target site in a blood vessel of a human patient, and a sensing element positioned along the distal portion. The sensing element can be a pressure sensing element, a flow sensing element, an impedance sensing element, and/or a temperature sensing element. The system can further include a controller configured to obtain one or more measurements related to a physiological parameter of the patient via the sensing element. Based on the measurements, the controller can determine the physiological parameter and compare the parameter to a predetermined threshold. Based on the comparison, the controller and/or the operator can assess the likelihood of the patient benefiting from neuromodulation therapy.

A living-body information measuring device includes plural light-emitting elements, a light-receiving element that is disposed at a position at different distances from the light-emitting elements and that receives reflected light beams that are reflected from a living body when the light-emitting elements emit light beams toward the living body, a control unit that controls the light-emitting elements so that the light-emitting elements successively emit the light beams, and a measurement unit that measures living-body information at plural depths in the living body by using the reflected light beams that are successively received by the light-receiving element.

Various embodiments are described herein for a system and a method for monitoring aortic pulse wave velocity and blood pressure. A pulse sensor is located on the exterior of an individual's body at a sensor location that allows acquisition of the pulse signal such that a reflected wave component of the pulse signal is present and allows characterization of reflected wave onset. A pulse signal is received from the pulse sensor and a reflected wave onset point is identified in the pulse signal. A reflected wave ratio is determined at the reflected wave onset point and the aortic pulse wave velocity is determined from the reflected wave ratio. The aortic pulse wave velocity can be displayed to the individual, transmitted to an external device and/or stored.

A sensor includes a light emitting element, a photodetector element for receiving light emitted by the light emitting element, and a circuit board having the light emitting element and the photodetector element mounted thereon. A light emitting surface of the light emitting element is facing the circuit board which is provided with a light-transmitting portion for transmitting the light emitted by the light emitting element.

A sensor includes a light emitting element, a photodetector element for receiving light emitted by the light emitting element, and a circuit board having the light emitting element and the photodetector element mounted thereon. A light emitting surface of the light emitting element is facing the circuit board which is provided with a light-transmitting portion for transmitting the light emitted by the light emitting element.

An electronic device according to one aspect includes a blood flow data acquisition unit configured to acquire information related to blood flowing inside a living body as blood flow data based on Doppler shift, a power spectrum calculator configured to calculate a power spectrum of the blood flow data based on the blood flow data, and an outline index calculator configured to calculate an outline index from the power spectrum. An electronic device according to one aspect further includes an estimator configured to estimate viscosity of the blood based on the outline index, and the estimator is configured to display an estimation result of the viscosity of the blood on a display.