An optical speckle receiver for receiving a speckle signal from a sample, the optical speckle receiver comprising an optical detector and an aperture and/or lens array. The aperture and array respectively comprise a plurality of apertures or lenses and is located between the sample and the optical detector such that the received speckle pattern is obtained from multiple discrete sample locations.

An input interface is configured to receive a signal corresponding to a quantity of light that has passed through a living tissue of a subject. A pressurization controller is configured to control a pressurizing operation performed with a pressurization device attached to a body of the subject, thereby changing at least one of a thickness of the living tissue, an amount of blood contained in the living tissue, an amount of cellular interstitial fluid contained in the living tissue, an amount of blood flowing into the living tissue, and an amount of blood flowing out from the living tissue. A processor is configured to acquire, from a temporal change of the signal due to the pressurizing operation, a feature quantity that is used for estimating at least one of a physiological state of the living tissue and a disease state of the subject.

The present invention provides a pulse diagnosis device including at least one bellow, at least one sensor, and a locating element. The bellow has a sensing surface having a first end and a second end opposite to each other. The sensor is disposed on the sensing surface and has a sensing area at least partially extending from the first end to the second end or protruding from the second end. The locating element is at least partially disposed along the second end to position the sensor at the second end, wherein the sensing area does not overlap with the locating element at least partially.

A photoplethysmography (PPG) device includes an equipment module which includes a photodetector and first and second light emitting diodes (LED's) adapted to emit light of first and second wavelengths, respectively. The PPG device also includes a mask covering the patient facing extremity of the equipment module so that when the device is applied to a patient the mask is situated between the patient and the patient facing extremity. A processor is adapted to control drive current and/or operating time of the second LED to achieve an elevated localized body tissue temperature of a patient to which the PPG device is applied.

A photoplethysmography (PPG) device includes an equipment module which includes a photodetector and first and second light emitting diodes (LED's) adapted to emit light of first and second wavelengths, respectively. The PPG device also includes a mask covering the patient facing extremity of the equipment module so that when the device is applied to a patient the mask is situated between the patient and the patient facing extremity. A processor is adapted to control drive current and/or operating time of the second LED to achieve an elevated localized body tissue temperature of a patient to which the PPG device is applied.

The present disclosure describes a system for detecting abnormal blood pressure or blood volume in a user, the system comprising a processing system; a pulse transit time (PTT) detection system for providing a PTT signal indicative of a PTT of the user to the processing system, wherein PTT of the user is used as a surrogate for a blood pressure (BP) of the user; and an electrodermal activity (EDA) detection system for providing an EDA signal indicative of an EDA of the user to the processing system; wherein the processing system processes the PTT signal and the EDA signal to determine an index indicative of an abnormal blood pressure or blood volume of the user.

Embodiments of the present disclosure relate to a system and method for determining a risk, onset, or presence of hypovolemia based on one or more features of a plethysmographic waveform during a patient breathing cycle. For example, a hypovolemic patient may exhibit characteristic changes in pulse amplitude or stroke volume during inhalation and exhalation relative to a healthy patient. Further, a trend or pattern of such features may be used to assess the patient's fluid condition.

Embodiments of the present disclosure relate to a system and method for determining a risk, onset, or presence of hypovolemia based on one or more features of a plethysmographic waveform during a patient breathing cycle. For example, a hypovolemic patient may exhibit characteristic changes in pulse amplitude or stroke volume during inhalation and exhalation relative to a healthy patient. Further, a trend or pattern of such features may be used to assess the patient's fluid condition.

A system includes an electrical tomography system and a volume estimation system. The volume estimation system is configured to reconstruct an initial impedance image based at least partially on received electrical tomography data of a domain, receive prior information associated with the domain, enhance the initial impedance image based at least partially on the received prior information to generate an enhanced impedance image, and based at least partially on the enhanced initial impedance image, generate a volumetric image of a region of interest of the enhanced impedance image, wherein the volumetric image represents a plurality of values indicating a volume of a fluid.

An ear-worn device includes a speaker, an optical emitter, an optical detector, a processor, and a housing configured to be positioned within an ear of a subject, wherein the housing encloses the speaker, optical emitter, optical detector, and processor. The housing includes at least one window that exposes the optical emitter and optical detector to the ear of the subject, and the housing includes at least one aperture through which sound from the speaker can pass. Light transmissive material is located between the optical emitter and the at least one window and is configured to deliver light emitted from the optical emitter to an ear region of the subject at one or more predetermined locations. Light transmissive material is positioned between the optical detector and the at least one window and is configured to collect light external to the housing and deliver the collected light to the optical detector.