A catheter-based baro-hydrometer device measures or otherwise monitors esophageal function. The device includes a segmented balloon design, including a first and second balloon whose fill volumes can be independently controlled. In general, the device leverages secondary peristalsis related to balloon distention in order to study esophageal function. Pressure sensors coupled to the balloons record pressure data, which can be classified and processed to measure or otherwise monitor esophageal function.

According to one aspect, an implantable medical device may include an anchor assembly configured to anchor the medical device to a body lumen. The implantable medical device may also include a capsule. The capsule may include a pH sensor. The pH sensor may be configured to measure a pH of contents within the body lumen. The capsule may also include a power source, a controller, and an impedance sensor. The impedance sensor may be configured to measure an impedance within the body lumen.

Disclosed are catheter systems and methods of using the catheter system to acquire mucosal impedance data of a patient. Also disclosed are methods of classifying or otherwise identifying esophageal conditions in a subject based on mucosal impedance data acquired using a catheter system. Unlike conventions systems that require subjective input from a physician to render a diagnosis, the systems and methods described herein can utilize the mucosal impedance measurements to generate a probability that the subject's esophagus corresponds to an esophageal condition or a set of esophageal conditions. In one embodiment, a classification model is used to generate the probability. The classification model may generate the probability based at least in part on a change in the mucosal impedance measurements between a distal location and a proximal location on the subject's esophagus.

There is provided a system for managing reflux during an enteral feeding, comprising: (i) a non-transitory memory having stored thereon a code for execution by at least one hardware processor of a computing device, the code comprising: code for receiving electrical signals outputted by at least one reflux event sensor disposed within a digestive system of a patient; code for determining a gastric reflux event based on an analysis of the electrical signals; code for outputting instructions to pause enteral feeding of the patient by a feeding controller that regulates enteral feeding of the patient using an enteral feeding tube positioned within the digestive system of the patient; and (ii) an evacuation controller that directs back-flow of digestive contents from the digestive system of the patient to an external evacuation reservoir through an evacuation tube.

A method for predicting a cancer staging score from medical image data includes receiving patient data for a plurality of patients, where patient data for each of the plurality of patients includes one or more of an image volume of a suspected tumor in an organ, blood test data, demographic data, and ground truth tumor staging scores for the suspected tumor in the organ, extracting features from the patient data, and using the features extracted from the patient data to train a classifier to predict a cancer staging score for a new patient from one or more of an image volume of a suspected tumor in the organ, patient blood test data and patient demographic data of that new patient.

An anatomical manometry catheter system, comprising a plurality of balloons on the distal end and being configured to be inflatable and/or deflatable. The system includes a connector assembly coaxially aligned with the catheter assembly, the connector assembly being connectable to the proximal end of the catheter. The connector assembly may have a connector interface connected to the proximal end of the catheter. The connector assembly may include a manifold comprising a plurality of channels configured to deliver the pressure transmission medium therethrough toward a respective catheter lumen for inflating one or more balloons. The connector assembly may include a charging mechanism fluidly coupled to the catheter that facilitates inflating each balloon of the plurality of balloons by a common actuating mechanism so as to simultaneously charge each balloon of the plurality of balloons.

A catheter suitable for delivering an electric current to the body, in particular a catheter having electrodes that can be positioned independently of the main elongate shaft of the catheter. More particularly the catheters include a movable sleeve that incorporates the electrodes. A movable sleeve includes one or more electrodes and advances in the construction of the electrodes and related components is disclosed. Methods for positioning electrodes at a treatment site in the body for diagnostic or therapeutic applications, particularly electrical pharyngeal stimulation are also disclosed.

An appliance (1) for enteral nutrition by means of a probe of the type comprising a tubular element of elongated shape and substantially flexible which defines a feeding channel open at the extremities for the introduction of nutritional substances in the stomach of a patient and which comprises at least a first inflatable balloon for detecting the pressure inside the esophagus of a patient, the tubular element comprising at least a first inlet/outlet mouth for the air in/from the first balloon, the appliance (1) further comprising: at least a pneumatic circuit (3) having pumping means (4) associable at least with the first inlet/outlet mouth for inflating/deflating the first balloon; processing means (8) comprising: detection means which can be connected to the first balloon to detect the patient's oesophageal pressure (p.sub.es); reading means of the pressure of the respiratory tract (p.sub.aw) which can be connected to an external detection device; calculation means operatively connected to the detection means and to the reading means and able to calculate at least the transpulmonary pressure (p.sub.tp); graphic display means (10) operatively connected to the processing means (8) and able to display at least one of the oesophageal pressure (p.sub.es), the pressure of the respiratory tract (p.sub.aw) and the transpulmonary pressure (p.sub.tp).

A mucosal impedance measuring apparatus detects and measures a condition of mucosa. The mucosal impedance measuring apparatus includes a catheter comprising a tube, impedance sensing electrodes on an exterior surface of the catheter, a balloon mounted on the tube in which the balloon is capable of inflation and deflation, and an impedance measuring system. The impedance measuring system is adapted to measure a pressure-regulated impedance measurement of the mucosa that is indicative of the condition of the mucosa when the balloon is inflated and the impedance sensing electrodes direct an electric current through mucosa while the balloon is pressed against the mucosa.

Disclosed are a cardiogenic interference identification method for a medical ventilation device, and a medical ventilation device. The method includes acquiring a first signal and a second signal obtained by a medical ventilation device monitoring a ventilation object, the first signal including a flow velocity signal; according to the flow velocity signal and the second signal, identifying a fluctuation in the flow velocity signal; acquiring a fluctuation characteristic of the fluctuation and, on the basis of the fluctuation characteristic of the fluctuation, identifying cardiogenic interference in the fluctuation. The present method identifies cardiogenic interference on the basis of a signal collected by the medical ventilation device itself, and a physiological signal from an external device is not required. The method has a significant value for clinical.