This invention relates to an ingestible drug delivery device configured for wireless communication with other ingestible drug delivery devices.

Methods and apparatus for detection of tissue damage in patients using a medical device for an extended period of time are disclosed.

Methods and apparatus for detection of tissue damage in patients using a medical device for an extended period of time are disclosed.

A body electrode unit includes a body electrode and a release sheet to which the body electrode is attached. The body electrode includes a first electrode configured to stimulate a muscle of a body, a second electrode, and a third electrode. The second electrode and the third electrode are configured to detect a physiological signal from the muscle that is stimulated by the first electrode. The body electrode also includes a first connection portion arranged between the first electrode and the second electrode, and a second connection portion arranged between the third electrode and one of the first electrode and the second electrode. The first connection portion has at least one first direction changing part configured to change a direction in which the first connection portion extends, such that at least one of a distance and an angle between the first electrode and the second electrode is adjustable.

The present disclosure provides apparatuses and methods for measuring capacitance as an indication of susceptibility to the formation of a diabetic foot ulcer.

The present disclosure provides apparatuses and methods for measuring capacitance as an indication of susceptibility to the formation of a diabetic foot ulcer.

Described are methods and devices (100) for measuring a sweat property of skin (12) in response to at least one test material or component (172, 174, 176, 178). Embodiments of the device include a plurality of different sweat stimulation sites. The Sweat stimulation sites may include one or more sweat stimulant reservoirs (142, 144, 146, 148) configured to deliver a sweat stimulant to the surface of the skin (12). Embodiments may also include at least one electrode (150, 152, 154, 156, 158) for measuring a sweat property or to iontophoretically deliver the sweat stimulant from the reservoir (142, 144, 146, 148). In embodiments, the sweat stimulant is selected from acetylcholine, carbachol, methacholine, bethanechol, muscarine, pilocarpine, oxotremorine, and combinations thereof.

Described are methods and devices (100) for measuring a sweat property of skin (12) in response to at least one test material or component (172, 174, 176, 178). Embodiments of the device include a plurality of different sweat stimulation sites. The Sweat stimulation sites may include one or more sweat stimulant reservoirs (142, 144, 146, 148) configured to deliver a sweat stimulant to the surface of the skin (12). Embodiments may also include at least one electrode (150, 152, 154, 156, 158) for measuring a sweat property or to iontophoretically deliver the sweat stimulant from the reservoir (142, 144, 146, 148). In embodiments, the sweat stimulant is selected from acetylcholine, carbachol, methacholine, bethanechol, muscarine, pilocarpine, oxotremorine, and combinations thereof.

Embodiments of the disclosure provide a system for predicting onset of sleep. The system includes a user worn device that includes a plurality of primary sensors to collect a plurality of primary data of a user, a first processor, in communication with the primary sensors, to receive the data and further process the data, wherein the processor determines an onset of sleep data in the user, a first communications module, in communication with the processor, transmits the onset of sleep data, a secondary device, that collects secondary data of the user, a secondary processor, that receives the onset sleep data from the first communications module and secondary data from the at least one secondary sensor, and combines the received onset sleep data and the secondary data to determine whether an onset of sleep event is possible and warn the user about the onset of sleep event.

Embodiments of the disclosure provide a system for predicting onset of sleep. The system includes a user worn device that includes a plurality of primary sensors to collect a plurality of primary data of a user, a first processor, in communication with the primary sensors, to receive the data and further process the data, wherein the processor determines an onset of sleep data in the user, a first communications module, in communication with the processor, transmits the onset of sleep data, a secondary device, that collects secondary data of the user, a secondary processor, that receives the onset sleep data from the first communications module and secondary data from the at least one secondary sensor, and combines the received onset sleep data and the secondary data to determine whether an onset of sleep event is possible and warn the user about the onset of sleep event.