An end effector having loop members with electrodes thereon and are usable with catheter-based systems to measure or provide electrical signals. The end effector can include three loop members that are non-coplanar when expanded unconstrained that become contiguous to a planar surface when the loop members are deflected against the surface, a mechanical linkage that joins the loop members at a distal vertex of the end effector. The end effector may have a lateral gap length between laterally adjacent electrodes approximately twice that of a longitudinal gap length between longitudinally adjacent electrodes. In some configurations, longitudinal electrode bipole pairs having a gap distance approximately equal to the lateral gap distance may be provided by bypassing every other electrode in the longitudinal direction.

A system for tracking a catheter in a patient. The system including a plurality of surface electrodes and a surface patch attached to the patient and a processor coupled to the plurality of surface electrodes and the surface patch. The processor determines a location of at least one of the plurality of surface electrodes, stores locations of the surface patch and the at least one of the plurality of surface electrodes, determines a three-dimensional shell shape that corresponds to a portion of the patient, determines a model of an impedance tracking field in at least a portion of the three-dimensional shell shape, injects current through one or more of the plurality of surface electrodes, fits measured voltages from the catheter to the model of the impedance tracking field to determine locations of the catheter, and provides therapy to the patient based on the locations of the catheter.

An integrated device package sized and shaped to fit in a small space, such as within a body lumen or cavity of a human patient, is disclosed. The integrated device package includes a package substrate and integrated device dies. The first and second integrated device dies are angled relative to one another about the longitudinal axis by a fixed non-parallel angle.

Embodiments of the present disclosure include a medical device. The medical device can include a catheter shaft that includes a proximal end and a distal end, the catheter shaft defining a catheter shaft longitudinal axis. A flexible tip portion can be located adjacent to the distal end of the catheter shaft, the flexible tip portion comprising a flexible framework, wherein the flexible framework is curved about a transverse framework axis that is disposed transverse to the catheter shaft longitudinal axis without application of a force external to the medical device. A plurality of microelectrodes can be disposed on the flexible framework and can form a flexible array of microelectrodes adapted to conform to tissue.

Navigation and tissue capture systems and methods for navigation to and/or capture of selected tissue using the innate electrical activity of the selected tissue and/or other tissue are described. In the context of left atrial appendage closure, the systems and methods can be used to navigate to the left atrial appendage and capture/control the appendage while a closure instrument (suture, clip, ring) is placed over the appendage and tightened down or a closure method (ablation, cryogenic procedures, stapling, etc.) is performed to close the left atrial appendage. The use of innate electrical activity for navigating devices may be used in connection with other tissues and/or areas of the body.

A transmitting element for generating a magnetic field for tracking of an object includes a first spiral trace that extends from a first outer origin inward to a central origin in a first direction. A second spiral trace can extend from the central origin outward to a second outer origin in the first direction. The second spiral trace can extend from the central origin to the second outer origin in the first direction. The first spiral trace and the second spiral trace can be physically connected at the central origin to form the fluorolucent magnetic transmitting element and at least a portion of the first spiral trace overlaps at least a portion of the second spiral trace.

Systems and method for remote field measurement-based mapping of anatomical structures (e.g., using impedance image of electrical fields) are described. In some embodiments, an image of features within a target region is produced by analysis of a spatial pattern of field measurements made in a measurement region remote from the target region features; for example, but not exclusively, by treating the spatial arrangement of field measurements in some portion of the measurement region as indicating the spatial (e.g., angular and/or distance) arrangement of features (e.g., anatomical structure of topography and/or tissue type) in the target region.

A system and method for tracking catheter electrode locations with the body of a patient during an MRI scan sequence includes mitigation logic configured to identify one or more impedance measurements that were taken during potentially noise-inducing conditions (i.e., magnet gradients, RF pulses), and were thus subject to corruption by noise. The mitigation logic is configured to replace the potentially corrupt impedance measurements with previously-obtained impedance measurements taken from an immediately preceding acquisition cycle (e.g., from a previous time-slice).

An apparatus includes a body and a shaft assembly extending distally from the body. The shaft assembly includes a proximal portion defining a longitudinal axis, a steerable portion distal to the proximal portion, and a distal portion distal to the steerable portion. The steerable portion is operable to drive the distal portion laterally away from and toward the longitudinal axis. The shaft assembly further includes at least one flex circuit assembly. The at least one flex circuit assembly includes a first navigation sensor configured to measure impedance signals that indicate a real-time position of the steerable portion. The at least one flex circuit assembly further includes a second navigation sensor configured to measure magnetic signals that indicate a real-time position of the steerable portion.

A flexible circuit that is substantially planar may be assembled into an electrophysiologic catheter. The flexible circuit may include various location sensing portions and force sensing portions. The flexible circuit may be deformed in a manner that improves the catheter's functionality concerning force feedback and location feedback, and then further deformed to be assembled into a small volume of the catheter.