An imaging probe comprises a camera or endoscope with an external detector array, in which the probe is sized and shaped for surgical placement in an eye to image the eye from an interior of the eye during treatment. The imaging probe and a treatment probe can be coupled together with a fastener or contained within a housing. The imaging probe and the treatment probe can be sized and shaped to enter the eye through an incision in the cornea and image one or more of the ciliary body band or the scleral spur. The treatment probe may comprise a treatment optical fiber or a surgical placement device to deliver an implant. A processor coupled to the detector can be configured with instructions to identify a location of one or more of the ciliary body band, the scleral spur, Schwalbe's line, or Schlemm's canal from the image.

An endoscope includes an insertion unit, an operation unit, an emission end, a first light guide and a second light guide that guide illumination light emitted from a light source unit to the emission end, a lens member that suppresses a variation in a relative intensity of each color light of the illumination light, and a connection unit that optically connects the first light guide, the second light guide, and the lens member; and the lens member is disposed between the first light guide and the second light guide, and the connection unit and the lens member are provided in the operation unit.

An imaging module includes an imager having an optical member on a light receiving surface, an electronic component having a front surface facing the same direction as the one to which an incidence surface of the optical member faces, a resin portion that has a first surface flush with the incidence surface of the optical member and the front surface of the electronic component, and a second surface that is a surface on a side opposite to the first surface while having the imager and the electronic component being embedded therein such that the incidence surface and the front surface are exposed to the first surface, an external connection terminal provided on the second surface, and a through wiring that extends through the resin portion to connect at least one of the imager and the electronic component with the external connection terminal.

An endoscope may have a shaft having a distal end portion and a proximal end portion. The endoscope may also have a first objective arranged at the distal end portion and a first optical axis. The endoscope may also have a second objective arranged at the distal end portion and a second optical axis. The endoscope may also have a lens system disposed within the shaft between the distal end portion and the proximal end portion, the lens system having an optical axis. The first objective and the second objective may be both optically coupled to the same lens system such that first parallel rays from the first objective and second parallel rays from the second objective are input into the lens system. The lens system may be an optical relay system may have at least one relay group or a tube lens group.

Systems and methods involve abrading a patient lung airway wall to reduce mucus production therein. Exemplary techniques include rotationally and/or linearly oscillating an abrasive material against the airway wall so as to damage mucus producing tissues, for example by removing goblet cells, while destroying less than the entire airway wall. The abrasive material may be present on the surface of an expandable balloon body or another expandable device, which can be delivered to the patient treatment site via a bronchoscope. In some cases, the abrasion techniques can cause cell damage or death at a controlled or predetermined tissue depth.

An imaging optical system according to the present disclosure includes: an aperture stop; an image-forming optical system that causes an image to be formed toward an imaging plane of an image sensor; and an optical phase modulator that includes a substance having a birefringence index, and gives two pupil functions to the image-forming optical system. The following conditional expressions are satisfied:

1≤(2×L×tan(w)+D)/D<1.4   (1)

λ/4*0.75<Re<λ/4*1.1   (2), where L: a distance between the aperture stop and the optical phase modulator; D: an aperture diameter (diameter) of the aperture stop; w: a maximum angle of incidence of a principal light ray that enters the aperture stop; λ: a wavelength of light; and Re: phase retardation caused by birefringence of the optical phase modulator.

Provided is an endoscope having a tip at a distal section thereof, the tip includes a plurality of imaging units, at least one of the imaging units includes at least two optical lens assemblies and at least one optical sensor associated with the at least two optical lens assemblies, wherein each optical lens assembly has a different depth of field, thereby allowing to obtain a multi-focal image of a body cavity. Further provided are systems comprising the endoscope and methods of using the same in various endoscopic procedures.

An imaging system (100) comprises a multimode waveguide (Wm) configured to receive input light (Li) from a light source (20) into its proximal side (13p) and output a corresponding speckle pattern (Pn) based on the input light (Li) out of its distal side (13d) for illuminating a sample (S) to be imaged. A single-mode waveguide (Ws) is connected to the multimode waveguide (Wm) for coupling the input light (Li) from the light source (20) to the multimode waveguide (Wm). The multimode waveguide (Wm) has a relatively short length (Zm) and relatively high flexural rigidity (R) for maintaining a unique relation between the input characteristic (λ,A) of the input light (Li) into the multimode waveguide (Wm) and a spatial distribution (Ixy) of the speckle pattern (Pn). The single-mode waveguide (Ws) may be relatively long and flexible (F) for allowing movement of the short rigid multimode waveguide (Wm).

The invention relates to a subassembly (1) for an objective (10), in particular for a long and slim optical image transmission system, for example an endoscope, an objective (10) and an optical image transmission system, as well as methods for manufacturing a subassembly and an objective. The subassembly (1) comprises a prism (2) and an aperture element (3), wherein the prism (2) and the aperture element (3) are fixedly connected to each other, preferably by means of a putty or via direct bonding.

A system is disclosed that includes an optical fiber including a first optical module and a gate. The gate can be capable of moving between closed and opened states to form a slit. At least one storage medium can be included having encoded thereon executable instructions that, when executed by the at least one processor, cause the system to carry out a method including directing light from the first optical module through the slit onto the stone to form a pair of lines with a spacing between the pair of lines; and determining a size of the stone, based on a distance from a distal tip of the optical fiber and the spacing between the pair of lines.