The present system is directed in various embodiments to devices, systems and methods for detection, evaluation and/or monitoring olfactory dysfunction by measuring and determining the patient's olfactory detection threshold for the left and the right nostril. In some cases, the present invention relates to devices, systems and methods for detecting an asymmetric differential in a patient's relative olfactory detection and/or identification threshold (left vs right nostril) which, when present, may be used as a device to detect, diagnose and/or monitor olfactory deterioration resulting from Alzheimer's disease, and/or the efficacy of treatment regimens therefor over time. Alternatively, general olfactory dysfunction may be evaluated and/or monitored without regard to the individual nostril's performance.

The fat burning analyzer includes a sampling part, an analysis unit and a processing unit. The sampling part collects a breath sample from the user, information on the conditions of the breath sample collection, and provides a sampling signal correlated to the collection condition of the breath sample. The analysis unit provides a detection signal corresponding to an acetone concentration in the collected breath sample and, as such, provides information on the breath acetone of the user (during exercise or resting). The processing unit receives the sampling signal and/or detection signal, and evaluates the sampling signal and/or the detection signal. The evaluation provides information correlated to the fat burning intensity of the user. These information can be provided as an output signal by the processing unit. Accordingly, the processing unit is equipped to provide an output signal correlated to the fat burning intensity of the user.

An obstructive sleep apnea detection device including an optical engagement surface adapted to engage a user's skin; a light source adapted to emit light from the optical engagement surface; a photodetector adapted to detect light at the optical engagement surface and to generate a detected light signal; a position sensor adapted to determine patient sleeping position; a controller adapted to determine and record in memory blood oxygen saturation values computed from the detected light signal and user position information from the position sensor; and a housing supporting the optical engagement surface, the photodetector, the light source, the position sensor, and the controller.

Various embodiments of the disclosed technology present a structural foundation for volumetric flow reconstructions for expiratory modeling enabled through multi-modal imaging for pulmonology. In some embodiments, this integrated multi-modal system includes infrared (IR) imaging, thermal imaging of carbon dioxide (CO.sub.2), depth imaging (D), and visible spectrum imaging. These multiple image modalities can be integrated into flow models of exhale behaviors enable the creation of three-dimensional volume reconstructions based on visualized CO.sub.2 distributions over time, formulating a four-dimensional exhale model which can be used to estimate various pulmonological traits (e.g., breathing rate, flow rate, exhale velocity, nose/mouth distribution, tidal volume estimation, and CO.sub.2 density distributions). Various embodiments also enable the accurate acquisition of numerous pulmonary metrics that are then stored within distributed systems for respiratory data analytics and feature extraction through deep learning embodiments.

Various embodiments of the present technology present a structural foundation for respiratory analysis of turbulent exhale flows through a technique called Thin Medium Thermal Imaging (TMTI). TMTI is a respiration monitoring method that uses a thin medium and thermal imaging to sense breathing activity. This technique is presented as an alternative to existing non-contact methods of respiratory analysis. As with all non-contact methods, remote monitoring of patients' respiratory behaviors preserves patient comfort. However, unlike other respiratory monitoring methods, the TMTI method monitors respiration directly, and can therefore provide more respiratory information than other non-contact methods. Various embodiments may make use of different medium materials, different measurement setups, additional thermal imaging cameras and sensors, and setups with entertainment media such as Virtual Reality (VR). Various software resources may be used to process data produced from the TMTI method, such as image processing, signal processing, and machine learning algorithms.

An Internet-based disease monitoring system may include a network-based disease sensor device, which is coupled to a sensor, such as a spirometer. A remote server may be coupled to the network-based disease sensor device to provide analysis of input signals from the sensor. The remote server may be able to provide various services for grouping or handling functions relating to such input signals. A service may provide the ability to aggregate input signals from multiple sensors coupled to sensor devices and provide predictive modeling or statistical analysis, which may then be used to adjust future input signals. A service may also contain instructions how to handle billing based on usage of the network-based disease sensor device.

An obstructive sleep apnea detection device including an optical engagement surface adapted to engage a user's skin; a light source adapted to emit light from the optical engagement surface; a photodetector adapted to detect light at the optical engagement surface and to generate a detected light signal; a position sensor adapted to determine patient sleeping position; a controller adapted to determine and record in memory blood oxygen saturation values computed from the detected light signal and user position information from the position sensor; and a housing supporting the optical engagement surface, the photodetector, the light source, the position sensor, and the controller.

Vital sign information of a subject is determined using a marker for application to the subject. The marker is configured to change an optical property due to a mechanical manipulation of the marker caused by a physiological process of the subject. The change in the optical property is detected and analyzed to determine vital sign information of the subject.

The chronic nature of asthma necessitates regular self-monitoring of respiratory function in susceptible individuals, however the available devices for performing the necessary measurements are either inaccurate or expensive and bulky. The present invention provides a small, cheap spirometer for efficient, accurate and convenient measurement of breathing characteristics.

The present system is directed in various embodiments to devices, systems and methods for detection, evaluation and/or monitoring olfactory dysfunction by measuring and determining the patient's olfactory detection threshold for the left and the right nostril. In some cases, the present invention relates to devices, systems and methods for detecting an asymmetric differential in a patient's relative olfactory detection and/or identification threshold (left vs right nostril) which, when present, may be used as a device to detect, diagnose and/or monitor olfactory deterioration resulting from Alzheimer's disease, and/or the efficacy of treatment regimens therefor over time. Alternatively, general olfactory dysfunction may be evaluated and/or monitored without regard to the individual nostril's performance.