The disclosure relates to devices, systems and methods for detecting markers in breath, more specifically volatile and non-volatile markers associated with pulmonary diseases such as, for example, asthma, chronic obstructive pulmonary disease (COPD), or cystic fibrosis (CF), in exhaled breath condensate (EBC).

A device (400) for delivering medication to a user includes a circular or elliptical body (410) that includes a mouthpiece (420), a flexible strip (401) of medication, a lever (424), and a mouthpiece cover (491), where the mouthpiece cover is rotatable about the body. An electronics module (120) includes a communication circuit (134), a power supply (126), a sensor system (128), and a switch. The lever is configured to actuate the switch when the lever is moved from a closed position to an open position. The lever is further configured to advance a dose of medication on the flexible strip when moved from the closed position to the open position. The switch switches the electronics module from an off state to an active state when the lever is actuated for a first time by a user. The electronics module is configured to not return to the off state thereafter.

A device (400) for delivering medication to a user includes a circular or elliptical body (410) that includes a mouthpiece (420), a flexible strip (401) of medication, a lever (424), and a mouthpiece cover (491), where the mouthpiece cover is rotatable about the body. An electronics module (120) includes a communication circuit (134), a power supply (126), a sensor system (128), and a switch. The lever is configured to actuate the switch when the lever is moved from a closed position to an open position. The lever is further configured to advance a dose of medication on the flexible strip when moved from the closed position to the open position. The switch switches the electronics module from an off state to an active state when the lever is actuated for a first time by a user. The electronics module is configured to not return to the off state thereafter.

A device for combined respiratory gas analysis and lung function test includes a gas quantity measuring device, a gas analysis device, and a multi-way valve configured for placement at least between a first valve path combination and a second valve path combination. A first gas path between the gas quantity measuring device and a second combined inlet/outlet opening is established while by-passing the gas analysis device with the first valve path combination of the multi-way valve, and a second gas path is established between a first combined inlet/outlet opening, the gas analysis device, the gas quantity measuring device, and the second combined inlet/outlet opening with the second valve path combination of the multi-way valve.

A device for combined respiratory gas analysis and lung function test includes a gas quantity measuring device, a gas analysis device, and a multi-way valve configured for placement at least between a first valve path combination and a second valve path combination. A first gas path between the gas quantity measuring device and a second combined inlet/outlet opening is established while by-passing the gas analysis device with the first valve path combination of the multi-way valve, and a second gas path is established between a first combined inlet/outlet opening, the gas analysis device, the gas quantity measuring device, and the second combined inlet/outlet opening with the second valve path combination of the multi-way valve.

An airflow perturbation device for measuring respiratory resistance of a patient breathing with the use of a ventilator comprises a sealed housing having a first port and a second port each configured to couple to a ventilator hose, a perturbation mechanism to periodically alter air flow resistance between the first port and the second port, a pneumotachometer comprising a flow sensor to measure airflow between the first port and the second port, a pressure sensor to measure a difference in air pressure between the first port and the second port, and a computing system comprising at least one processor configured to receive data from the flow sensor and pressure sensor. The computing system determines an airflow resistance based on the received data. Embodiments of the present invention further include a method and computer program product for measuring respiratory resistance of a ventilated patient in substantially the same manners described above.

An airflow perturbation device for measuring respiratory resistance of a patient breathing with the use of a ventilator comprises a sealed housing having a first port and a second port each configured to couple to a ventilator hose, a perturbation mechanism to periodically alter air flow resistance between the first port and the second port, a pneumotachometer comprising a flow sensor to measure airflow between the first port and the second port, a pressure sensor to measure a difference in air pressure between the first port and the second port, and a computing system comprising at least one processor configured to receive data from the flow sensor and pressure sensor. The computing system determines an airflow resistance based on the received data. Embodiments of the present invention further include a method and computer program product for measuring respiratory resistance of a ventilated patient in substantially the same manners described above.

The present invention relates to a device, system and a method for determining lung volume and parameters, and in particular, to such a spirometer device, system and method in which a non-occluding shutter is utilized allowing for continuous airflow through the flow tube.

The present invention relates to a device, system and a method for determining lung volume and parameters, and in particular, to such a spirometer device, system and method in which a non-occluding shutter is utilized allowing for continuous airflow through the flow tube.

A spiroergometry apparatus for detecting parameters of a respiratory gas. The spiroergometry apparatus has a main body, a measuring device, a computing unit and an energy store. The measuring device includes a sensor, which is provided on the main body, whereby it becomes possible to detect parameters directly in the respiratory gas flow, so that an in-situ detection of the parameters of the respiratory gas is made possible.