Kits, diagnostic systems and methods are provided, which measure the distribution of colors of skin features by comparison to calibrated colors which are co-imaged with the skin feature. The colors on the calibration template (calibrator) are selected to represent the expected range of feature colors under various illumination and capturing conditions. The calibrator may also comprise features with different forms and size for calibrating geometric parameters of the skin features in the captured images. Measurements may be enhanced by monitoring over time changes in the distribution of colors, by measuring two and three dimensional geometrical parameters of the skin feature and by associating the data with medical diagnostic parameters. Thus, simple means for skin diagnosis and monitoring are provided which simplify and improve current dermatologic diagnostic procedures.

Cosmetic method in which: a) a color is acquired from a region of the body of an individual, by using a device equipped with a color camera and by placing a color reference chart in the field of said camera during the acquisition; and b) using the device, and the color acquired in a), and optionally knowledge of the tanning pathways of various skin colors, at least one indication is delivered concerning skin type and/or at least one indication is delivered concerning at least one skin color obtainable by the individual via the pigmentation or depigmentation process and/or at least one indication is delivered concerning photoprotection and/or application or administration of a product intended to temporarily modify the color of the skin.

Systems, methods, and devices are provided for estimating bilirubin levels. In one aspect, a method for estimating the level of bilirubin in a patient includes receiving image data for at least one image including a region of the patient's skin and a color calibration target. Color-balanced image data for the skin region is generated based on a subset of the image data corresponding to the color calibration target and the skin region. The bilirubin level in the patient is estimated based on the color-balanced image data for the skin region.

Disclosed are a method and an apparatus for jaundice diagnosis based on an image. The method for jaundice diagnosis based on an image includes: receiving a jaundice diagnostic image acquired by photographing both a specific body part of a user and a reference object at a place where the user is positioned at present; generating color distortion information indicating a color distortion degree of the reference object included in the jaundice diagnostic image; generating a jaundice diagnostic correction image by correcting color distortion of the jaundice diagnostic image based on the color distortion information; and diagnosing a jaundice symptom for the user by using the jaundice diagnostic correction image.

A method for measuring an analyte includes identifying a test strip in a video stream generated by a camera based on at least one registration mark associated with the test strip depicted in the video stream, identifying application of a fluid dose to a deposit site formed on the test strip based on the video stream, activating a timer in response to the identification of the application of the fluid dose, generating at least one optical measurement of a reagent located at a measurement site on the test strip, and generating a measurement of an analyte in the fluid dose based on the at least one optical measurement of the reagent only in response to the at least one optical measurement being generated after a predetermined minimum time period has elapsed and prior to a predetermined maximum time period elapsing subsequent to the activating of the timer.

A perpetual bioinformatics and virtual colorimeter expert system platform is disclosed to remotely measure dermal and epidermal properties with precision and to enhance decision-making. Some embodiments of the system provide for virtual tristimulus colorimetry, wherein a capture device captures one or more dermal images of one or more skin area of a user. A color grid includes one or more permutations of a plurality of recorded predetermined colors. A scale of the color grid is recorded as being printed or projected at a predetermined size. Application of the virtual tristimulus colorimeter to one of the images is performed. As a result of this application the image is calibrated according to the virtual tristimulus colorimeter. In some embodiments the capture device may include a smartphone camera, interactive with the virtual tristimulus colorimeter smartphone application.

Reference imagery of dermatological conditions is compiled in a crowd-sourced database (contributed by clinicians and/or the lay public), together with associated diagnosis information. A user later submits a query image to the system (e.g., captured with a smartphone). Image-based derivatives for the query image are determined (e.g., color histograms, FFT-based metrics, etc.), and are compared against similar derivatives computed from the reference imagery. This comparison identifies diseases that are not consistent with the query image, and such information is reported to the user. Depending on the size of the database, and the specificity of the data, 90% or more of candidate conditions may be effectively ruled-out, possibly sparing the user from expensive and painful biopsy procedures, and granting some peace of mind (e.g., knowledge that an emerging pattern of small lesions on a forearm is probably not caused by shingles, bedbugs, malaria or AIDS). A great number of other features and arrangements are also detailed.

Cosmetic method in which: a) a color is acquired from a region of the body of an individual, by using a device equipped with a color camera and by placing a color reference chart in the field of said camera during the acquisition; and b) using the device, and the color acquired in a), and optionally knowledge of the tanning pathways of various skin colors, at least one indication is delivered concerning skin type and/or at least one indication is delivered concerning at least one skin color obtainable by the individual via the pigmentation or depigmentation process and/or at least one indication is delivered concerning photoprotection and/or application or administration of a product intended to temporarily modify the color of the skin.

A wearable device may be provided for detecting cumulative alcohol consumption. Such a wearable device may include an adhesive layer that adheres to skin and that allows sweat from the skin to pass through and a customizable ink layer that reacts irreversibly to change color along a gradient as ethanol is detected in the sweat. The customizable ink continues to increase color intensity along the gradient as ethanol continues to be detected in the sweat over time.

A perpetual bioinformatics and virtual colorimeter expert system platform is disclosed to remotely measure dermal and epidermal properties with precision and to enhance decision-making by offering expert diagnostic and predictive services. Some embodiments of the system, which map atypical skin discoloration may include capture means for capturing dermal images of the skin area of a user to be evaluated; control means for identifying a control tone of a user based on conditional parameters; classification means for classifying the discoloration tones from captured dermal images; measurement means for measuring discoloration tones outside the spectrum of standardized normal tones; and quantification means for calculating the severity of tone discoloration when compared to a control tone. In some embodiments the capture means may include a smartphone camera, and a virtual tristimulus colorimeter application.