Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

A head-mounted device capable of more highly accurately measuring the physical conditions of a wearer as a worker that are necessary for estimating the possibility of heat stroke is provided. A head-mounted device includes an outer shell; a first channel as a gap between a head of a wearer and the outer shell; a second channel provided in the outer shell and connected to the first channel; a fan configured to send air from one of the first channel and the second channel to the other; a salinity sensor configured to measure salt concentration of sweat of the wearer; a first humidity sensor configured to measure an absolute humidity of intake air entering one of the first channel and the second channel; and a second humidity sensor configured to measure an absolute humidity of exhaust air exiting from the other of the first channel and the second channel.

Provided is a sensor capable of suppressing deviation in the state where the sensor is in contact with a living body. A sensor 1 converts, to an electrical signal, the amount of a substance to be measured contained in a secretion from a living body H, the sensor 1 comprising: a sensor main body 10 having an electrode part 11 that is disposed on the contact surface side contacting the living body H and a substrate 12 that is disposed on the exposed surface side opposite to the contact surface; and a fixing part 20 for fixing the sensor main body 10 to the living body H, wherein the fixing part 20 has a flexible sheet 21 that is attached to the living body H and fixes the sensor main body 10 to the living body H, and a spacer part 22 that is disposed between the flexible sheet 21 and the exposed surface and has a thickness equal to or thicker than that of the sensor main body 10.

A portable device for measuring the state of health of a user configured to be carried/worn by the user and comprising at least one measurement unit and at least one electric battery supplying the measurement unit with electricity, said electric battery comprising at least two charging electrodes that are configured to cooperate with a charging device in order to electrically recharge the electric battery, among which at least two of the charging electrodes, referred to as charging and measurement electrodes, are configured so as to be in contact with the sweat of the user and are connected to the measurement unit in order to measure, in cooperation with said measurement unit, at least one physical parameter of the sweat of the user, in order to measure their state of health.

A sweat sensor device (200) with analytical assurance includes at least one sensor (220) for detecting a first analyte, and at least one calibration medium (270) containing at least the first analyte. When the first analyte in the at least one calibration medium (270) comes into contact with the at least one sensor (220), the calibration medium (270) provides a calibration of the at least one sensor (220). A sweat sensor device (200) may further include a carrier (240) having at least one aperture (220a) and a reservoir (254) for storing the at least one calibration medium (270). The at least one aperture (220a) provides fluidic access to the at least one sensor (220) from the reservoir (254).

The present invention provides an improved system, device, and method for determining a comprehensive state of health in real time using non-invasive patient testing. The invention characterizes disease and other states of health by simultaneously assaying both liquid and gas in a sample or samples. During metabolism, the body performs a large variety of biochemical reactions. Reaction products, reaction by-products, and breakdown products are transported by the circulatory system throughout the body. Many of these molecular products are labile and volatilize into gases from bodily liquids. In gas form, these compounds appear as volatile organic compounds (VOCs).

A wearable monitoring system includes a first flexible substrate encapsulating a current ramping system to provide a current to an electrode in direct contact with a predetermined location of skin of a user to promote bodily fluid secretion, and a second flexible substrate placed over the predetermined location, the second flexible substrate having an integrated electrochemical sensor to determine bodily fluid concentration levels secreted through the skin.

A wearable body fat combustion measurement device includes a housing including a first chamber with an opening, a fixing means attached to the housing and configured to bring the housing into close contact with a user's skin in a state in which the opening of the first chamber faces the user's skin, a measurement sensor disposed inside the first chamber and configured to generate an electrical signal according to an amount of acetone contained in a gas evaporated from sweat discharged from the user's skin and introduced into the first chamber through the opening, a reference sensor disposed outside the first chamber and configured to generate an electrical signal according to a concentration of a gas component contained in an ambient air and detectable by the measurement sensor, and a signal processor configured to process the electrical signals received from the measurement sensor and the reference sensor.

The present invention relates to systems and methods for assessing brain health and detecting neurological conditions. The invention more particularly relates to systems and methods for diagnosing neurological conditions and analyzing rain health from analysis of a biological fluid sample, such as a saliva sample, that looks for and determines the significance of peripheral markers of blood-brain barrier disruption. The present invention further provides a diagnostic system and method with a higher negative predictive value of brain injury than currently known tests are able to provide, so as to reduce the need for computerized tomography or magnetic resonance imaging scans to affirmatively determine that brain or cerebrovascular injury has not occurred, and thus to improve suspected brain injury patient health care while reducing the expense of such care.

Presented herein are systems, methods, and architectures related to functionalization of the metallic gates of field-effect transistors (FETs) and the use of the functionalized FETs as biochemical sensors in liquid samples. The functionalization can either be a molecularly imprinted polymer or a probe material. The functionalized FETs can be used in devices for analyte detection/quantification. In particular, the functionalized FETs are used in devices for the detection and/or quantification of cytokines (e.g. interleukin) and/or cholesterol (LDL or HDL).