Systems, devices, methods, and kits for monitoring one or more physiologic and/or physical signals from a subject are disclosed. A system including patches and corresponding modules for wirelessly monitoring physiologic and/or physical signals is disclosed. A service system for managing the collection of physiologic data from a customer is disclosed. An isolating patch for providing a barrier between a handheld monitoring device with a plurality of contact pads and a subject is disclosed.

Provided is a method of determining a concentration (C.sub.a) of a first analyte (a) in sweat excreted by a first sweat gland type at a first skin location (i) having the first sweat gland type and a second sweat gland type. The method comprises measuring a first concentration (I) of the first analyte in sweat excreted at the first skin location and measuring at least one parameter of sweat excreted by the second sweat gland type at a second skin location (ii) having the second sweat gland type but not the first sweat gland type. The at least one parameter is used to determine a dilution factor (II) which quantifies dilution of the first analyte by sweat excreted by the second sweat gland type at the first skin location. This dilution factor (II) is then used to correct the first concentration (I) so as to determine the concentration (C.sub.a). Further provided is an apparatus (100) for determining the concentration (C.sub.a).

A system for visualizing patient stress or discomfort during dental treatment. By visualizing a patients changing stress conditions during treatment, a clinician may react accordingly such as by stopping a treatment activity, slowing a treatment activity, refreshing anesthesia, etc. in order to improve the patients experience.

A potentiometric sensor that includes a housing and working electrode is provided. The housing includes a reference electrode, a first hydrogel containing hydrogel that contains a reference solution, and a salt bridge. The sensor is wearable and can be used for continuous on-body sweat measurements.

Devices for collecting and analyzing a fluid sample comprise a fluid-collecting porous material comprising at least one hydrophilic porous layer and one or more sensors adapted to provide a response to the presence of an analyte. The detectors are useful for collecting and analyzing a very small volume of sample and may include features that facilitate and direct flow of the sample through porous material.

An electrochemical physiological sensor configured to come into contact with the body fluid and including an absorber of a body fluid defining a first surface configured to at least come into contact with the body fluid and a second surface opposite to the first surface; and a circuit deposited on the second surface and configured to contact the body fluid when absorbed by the absorber; the absorber has a porosity substantially between 40% and 70% so that the body fluid is absorbed by the absorber and the circuit is deposited without penetrating the absorber.

Disclosed is a method for correlating a biomarker in a non-blood bodily fluid with the same biomarker in the blood of an individual, including: measuring, in a first period in time, the biomarker in non-blood bodily fluid and measuring the same biomarker in the blood of the same individual to establish an R ratio of [NBBF1]/[BB1], where [NBBF1] is the biomarker concentration in non-blood bodily fluid in the first period in time, and [BB1] is the biomarker concentration in the blood in the first period in time; storing the ratio in a memory; measuring, in a second period in time, the biomarker in non-blood bodily fluid to determine [NBBF2], where [NBBF2] is the biomarker concentration in the non-blood bodily fluid in the second period in time; and correlating the measured [NBBF2] with the R ratio to generate a correlated [BB2] biomarker concentration in the blood of the individual in the second period in time. Also disclosed is a device, apparatus, and method for correlating the glucose concentration in a non-blood bodily fluid such as saliva with the glucose in the blood of an individual.

An intelligent tooth health-care system and an intelligent tooth cleaning device thereof. The intelligent tooth cleaning device includes a plurality of sensors capable of detecting conditions of mouth and teeth of a user. The user may obtain data relating to his/her health when he/she cleans the teeth. The sensors also detect the movement of the intelligent tooth cleaning device. The data of movement are transmitted to a mobile device and input to a computer tooth-cleaning game executed in the mobile device, whereby the user is guided by the computer tooth-cleaning game to clean his/her teeth. The data obtained by the sensors can also be transmitted to a server in the cloud for health analysis.

Systems and methods for a self-powered wireless wearable sensor system include a freestanding triboelectric nanogenerator (FTENG), used as a power source for a wearable sensor. The FTENG includes stator panels and corresponding slider panels with a grating pattern. Movement, such as cardiovascular exercise causes the slider panel(s) to slide across the stator panel(s) inducing a charge and powering a wearable device sufficiently to support data transmission and continuous monitoring. An integrated self-powered wireless wearable sensor system includes a microfluidic sweat sensor patch which may be connected to lower-power wireless sensor circuitry for regulating power efficiently and is powered by the FTENG.

An auto-powered biosensor capable detecting a target molecule, and a method of powering the same, wherein the biosensor is fabricated with a microfluidics layer, a multimodal sensing layer comprising a biofuel cell and an electrode, and a logic circuit that may include a processor and non-transitory memory with computer executable instructions embedded thereon.